Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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Director, Program Management Jobs in North Carolina

Sort By: Relevance

$120K - $145K *

Transform complex technical programs into clear, actionable plans that drive member value. Collaborate with cross-functional teams to enhance processes, improve information flow, and deliver high-impa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$146K - $224K *

Elevate clinical development by leading the strategy for biopharma platforms. Drive product lifecycles, collaborate with cross-functional teams, and ensure compliance while transforming workflows into...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $185K *

Transform client value and operational performance by leveraging data-driven insights, financial modeling, and strategic solutions. Collaborate across teams to enhance service delivery and drive measu...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Accelerate progress at the forefront of transformation initiatives, managing complex, cross-functional programs to drive business process redesign and measurable outcomes across multiple teams and fun...

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$202K - $253K *

Elevate your leadership as you drive engineering excellence, overseeing multiple squads from prototype to production. Shape the roadmap, empower teams, and ensure quality delivery while staying techni...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$126K - $173K *

Champion the development of Provider Direct Connect capabilities, driving product vision and strategy while collaborating with cross-functional teams to enhance provider engagement and deliver scalabl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead a talented design team to shape the user experience across multiple platforms. Define interaction patterns, elevate design standards, and collaborate with cross-functional teams to deliver innova...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Optimize your career as a Technical Project Manager, overseeing equipment procurement and supply chains. Collaborate with cross-functional teams, manage budgets, and negotiate contracts to ensure proj...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $132K *

Join a team that's dedicated to managing diverse financial services projects. Oversee design, development, and construction phases while ensuring project goals are met. Collaborate with stakeholders t...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Join a team that's redefining the buyer experience in B2B software. As a Principal Product Manager, you'll lead strategy, drive product delivery, and enhance buyer trust across multiple platforms, ens...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $200K *

Engineer enterprise transformation initiatives by aligning strategic priorities with actionable plans across functions. Drive sustainable change, optimize processes, and enhance organizational effecti...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$148K - $214K *

Innovate customer experience and automation solutions to streamline real estate closings. Drive strategy, prioritize product roadmaps, and collaborate across teams to enhance operational efficiency an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $190K *

Join a team that's pioneering maritime awareness solutions by leading commercial sales in diverse sectors. Own the end-to-end sales pipeline, identify target verticals, and shape strategies to drive s...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$117K - $189K *

Pioneer global Orexin development programs by driving project management efforts. Partner with the Global Team Leader to oversee cross-functional teams, manage critical activities, and ensure project...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Contribute to the success of pharmaceutical programs by managing client relationships, overseeing daily operations, and driving performance. Collaborate cross-functionally to ensure program execution...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $294K *

Lead and mentor a high-performing design team, driving product design strategy and delivering user-centric solutions. Collaborate with stakeholders to enhance customer experiences and foster a culture...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $180K *

Lead organizational capability by bridging strategy and execution across diverse hospitality operations. Drive scalable frameworks and change management to enhance performance and sustain innovation a...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $130K *

Manage enterprise-wide MarTech programs, aligning cross-functional teams to drive B2C marketing initiatives. Translate business priorities into actionable plans, ensuring effective collaboration and m...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Take ownership of project execution from initiation to closeout, ensuring accountability for scope, schedule, budget, and customer satisfaction. Collaborate cross-functionally to drive successful and...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in delivering impactful projects by defining objectives, managing resources, and fostering stakeholder relationships. Drive innovation and quality in project execution while enhancing...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $210K *

Transform the contract management landscape for large-scale data center projects. Oversee RFx processes, negotiate contracts, and ensure compliance while collaborating with cross-functional teams to m...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Transform the future of business applications by leading strategy, delivery, and operations. Collaborate with multidisciplinary teams to enhance core processes and drive value through effective system...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$140K - $210K *

Drive data protection and forensic investigations, overseeing DLP platforms and automation. Lead a team to enhance security posture, manage insider risks, and ensure compliance across multi-cloud envi...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $138K *

Manage complex data center deployment projects, ensuring timely delivery and alignment among stakeholders. Oversee planning, execution, and closeout while maintaining budget and risk controls in fast...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$140K - $190K *

Shape the future of customer projects by leading strategic SaaS implementations, ensuring exceptional execution and stakeholder engagement. As a key player, you'll drive project success through proact...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.