Are you looking for high-paying Director of Information Systems jobs? You've come to the right place. We host a wide range of jobs in this category that pay $100K or more.
Directors of Information Systems oversee an organization's IT strategy and ensure that systems, infrastructures, and networks operate smoothly.
Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.
IT Divisional Program Manager (Wake Forest Baptist and Georgia Markets)
$114K - $171K *
Optimize technology initiatives across multiple facilities, ensuring alignment with operational priorities and enterprise standards. Collaborate with leaders to oversee projects, manage complex issues...
3 days ago
Director, Strategic Engagement, Life Sciences
$150K - $180K *
Deliver exceptional customer success as you lead a team to optimize strategic engagement, driving value realization and long-term relationships in a fast-paced healthcare technology environment...
3 weeks ago
$137K - $165K *
Unlock potential by leading enterprise data architecture initiatives that ensure accurate, secure, and accessible data. Drive data governance and cloud-native modernization while supporting advanced a...
3 days ago
Sr. Program Manager (Healthcare)
$120K - $140K *
Engage in leading complex, cross-functional programs for healthcare clients. Drive strategic initiatives, manage risks, and enhance stakeholder communication while delivering impactful results in a dy...
2 days ago
$100K - $130K *
Lead and manage electrical and controls projects from concept to completion, ensuring quality execution and client satisfaction through effective budget and resource management while prioritizing safe...
Reposted 1 week ago
$125K - $150K *
Empower our development teams by providing architectural oversight, enhancing brokerage applications through innovative solutions, and mentoring to elevate enterprise architecture standards in a colla...
Reposted 2 weeks ago
$110K - $125K *
Grow your career with this dynamic Accounting Manager role, where you'll ensure financial reporting accuracy, oversee monthly close processes, and collaborate cross-departmentally to enhance efficienc...
1 week ago
Senior Director, Strategic Deals & Commercial Excellence
$175K - $210K *
Lead the charge in shaping strategic enterprise deals, guiding negotiations and frameworks for complex transactions. Collaborate with executives to optimize deal execution and enhance revenue outcomes...
4 days ago
$110K - $130K *
Take ownership of key portfolio metrics, driving informed financial strategies and monitoring risks. Collaborate across teams to develop insights and tools, ensuring seamless operational execution and...
Reposted today
$105K - $125K *
Champion scalable integration solutions by leveraging SAP PI/PO and modern APIs. Collaborate with cross-functional teams to deliver robust data exchange and system communication, ensuring high quality...
2 weeks ago
AD / Director - Regulatory Affairs - FSP Team
$150K - $180K *
Deliver strategic regulatory leadership for global development programs, overseeing regulatory strategy and execution from late-stage clinical phases to marketing authorization while ensuring complian...
Reposted 1 week ago
$110K - $150K *
Lead a regional operations team driving healthcare excellence, client engagement, and financial performance. Blend strategic oversight with hands-on leadership to build high-performing operations and...
4 weeks ago
Ab Initio Administrator (Remote) (Systems Administrator 4) 30269
$97K - $130K *
Support and optimize Ab Initio systems for USPS, ensuring reliability and performance across environments. Collaborate on installations, configurations, and troubleshooting to enhance critical data pr...
2 weeks ago
$100K - $120K *
Join a dynamic team to lead the enhancement of safety initiatives, ensuring compliance and mentoring junior staff. Collaborate across departments to identify risks, conduct assessments, and foster a c...
2 weeks ago
$125K - $150K *
Drive the global strategy and execution of technology partnerships, enhancing revenue through active ecosystem engagement. You'll lead initiatives with top partners to boost joint go-to-market efforts...
4 days ago
$84K - $105K *
Empower teams by leading network installation projects, overseeing field operations, and ensuring quality and safety standards across various customer sites while mentoring junior technicians and coor...
2 weeks ago
Director, Scientific Affairs - Hemostasis
$190K - $252K *
Pioneer innovative scientific strategies in hemostasis, translating evidence into commercialization and stakeholder engagement. Build relationships with experts, support training, and align functions...
2 weeks ago
INGENYX- Senior Quality Management Systems Manager
$152K - $175K *
Shape and enhance the global Quality Management System for medical devices by driving compliance, governance, and continuous improvement while leading a dedicated team across multiple sites to meet re...
3 weeks ago
Director, Integrated Strategy (B2B)
$114K - $145K *
Collaborate to develop and execute integrated strategies for B2B brands. Lead cross-disciplinary teams and ensure alignment across creative, media, and content strategies to drive impactful results an...
2 weeks ago
Director of Program Development for Sponsored Research
$144K - $198K *
Champion the growth of a strategic research portfolio by leading funding initiatives, advancing partnerships, and developing complex, high-impact proposals that align with organizational priorities an...
1 week ago
Director of Sales - Transformers/EBOS
$125K - $150K *
Champion market expansion and strategic sales in the transformer industry, forging key client partnerships and driving compliance with industry standards while maximizing revenue and product line grow...
4 weeks ago
Director, Scientific Business Development
$160K - $200K *
Pioneer the integration of scientific innovation and business strategy in neuro-biotech. Drive deal execution, assess emerging CNS technologies, and shape partnerships to enhance preclinical and early...
Reposted today
$180K - $220K *
Develop and execute comprehensive tax strategies to optimize cash flow, ensure compliance, and support acquisition-driven growth. Lead a high-performing tax organization while advising executive leade...
Yesterday
Director, Business Development & Partnerships (Remote)
$150K - $180K *
Unlock growth by managing and enhancing partner relationships, crafting data-driven strategies, and driving collaborative initiatives. Leverage market insights to create innovative partnership solutio...
3 days ago
$125K - $150K *
Pioneer innovative sourcing strategies to reduce COGS for leading brands. Collaborate closely with executives to analyze, negotiate, and build procurement models from the ground up, impacting multiple...
1 week ago
What is the role of a Director, Information Systems?
A Director of Information Systems is responsible for overseeing the IT strategy of an organization, ensuring systems, infrastructures, and networks operate smoothly.
What qualifications do I need to be a Director, Information Systems?
Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.
What jobs are available on Ladders for Directors, Information Systems?
Ladders hosts a wide range of high-paying jobs for Directors of Information Systems. All jobs listed pay $100K or more per year.