Explore Director, Data Science opportunities for experienced leaders ready to shape how organizations use data. These roles combine technical depth with strategic direction, guiding teams that turn complex data into products, insights, and business outcomes. Ladders features vetted professional jobs paying $100,000 or more, including data science leadership opportunities across industries.
A Director of Data Science sets the vision for data science and machine learning initiatives, builds and mentors teams, and partners with executives and business leaders. Responsibilities may include prioritizing projects, overseeing model development and deployment, establishing measurement standards, and ensuring data practices support responsible, reliable decision-making.
Employers commonly seek a strong foundation in statistics, machine learning, experimentation, and data engineering, along with experience leading technical teams. Directors may also need to communicate complex findings clearly, connect analytical work to business goals, manage budgets and roadmaps, and collaborate across product, engineering, finance, and operations.
Director-level data science roles can be found in technology, financial services, healthcare, retail, media, and other data-intensive fields. Depending on the organization, leaders may focus on applied AI, customer analytics, risk modeling, personalization, forecasting, or the development of enterprise data science platforms. The scope and requirements vary by employer and team.
Search Ladders for Director, Data Science jobs paying $100,000 or more. Review role requirements, compare opportunities, and discover positions with vetted employers that align with your leadership experience and career goals.
$160K - $200K *
Champion data-driven decision-making by leading analytics strategy, driving enterprise-wide adoption of innovative solutions, and fostering collaboration across teams to enhance operational performanc...
Yesterday
Senior Technical Program Manager - Security
$150K - $180K *
The Security Program Manager will be responsible for securing OpenAI's critical product launches by coordinating security reviews and managing risks across cross-functional teams. This role ensures th...
Reposted 4 weeks ago
Director, Field Sales Engineering
$191K - $239K *
Lead the development and growth of a Sales Engineering team focused on new product incubation, driving adoption and revenue through strategic customer engagements and cross-functional collaboration to...
Reposted 1 week ago
Vice President, Business Intelligence Engineer
$150K - $180K *
Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...
Reposted 2 days ago
Sr. Software Engineer - Customer Facing Applied AI
$188K - $235K *
Develop AI-powered systems from concept to production, collaborating with clients to identify needs, prototype solutions, and ensure quality. Engage closely with users to iterate and enhance product f...
1 week ago
$100K - $120K *
Help us modernize our data platform by designing and building robust data models and analytics solutions. Collaborate with analysts and stakeholders to transform complex data into actionable insights...
1 week ago
Senior Scientific Director - Publications (Heme-Onc)
$150K - $180K *
Join us to lead the development and oversight of scientific content across therapeutic areas, ensuring strategic medical communication aligns with brand goals while managing a team and collaborating w...
3 weeks ago
$195K - $217K *
Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...
3 days ago
Director, Advanced Cooling Category Management, NA
$190K - $200K *
Drive global mechanical category strategy for advanced thermal management systems, ensuring optimal cost, quality, and reliability across a diverse supplier ecosystem while supporting scalable data ce...
Reposted 1 week ago
Manager of Statistical Programming
$132K - $165K *
Drive innovation in oncology diagnostics by leading statistical programming efforts, ensuring data integrity and compliance for clinical trials, while managing a team and collaborating cross-functiona...
1 week ago
Sr Manager, Operational Finance
$135K - $160K *
Advance financial operations by managing project finance teams, enhancing reporting processes, and supporting month-end close activities. Collaborate with stakeholders to ensure accurate revenue recog...
2 weeks ago
Sr Manager, Operational Finance
$135K - $160K *
Advance your career by managing financial operations for project teams, enhancing reporting accuracy, and leading financial analysis to support clinical trials and strategic decision-making...
2 weeks ago
Senior Manager, Discovery Operations
$120K - $145K *
Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...
Reposted 3 weeks ago
$225K - $275K *
Lead the charge in redefining Total Rewards strategy, enhancing compensation, equity, and benefits to attract and retain top talent while anticipating workforce shifts driven by AI and market trends...
Reposted 3 weeks ago
Senior Director, Clinical Pharmacology
$268K - $302K *
Lead strategic clinical pharmacology initiatives, guiding drug development from early to late stages. Collaborate cross-functionally, ensuring robust pharmacological strategies and regulatory complian...
Reposted yesterday
Senior Medical Director, Medical Affairs - Rheumatology (US)
$175K - $348K *
Transform clinical research through expert medical management and support. Collaborate with teams to ensure protocol integrity, provide training, and contribute to business development while maintaini...
Reposted yesterday
Office Manager, Multi-Site Operations
$135K - $155K *
Manage multi-site office operations, ensuring efficiency, safety, and a positive environment. Lead staff, oversee vendor relationships, and implement workplace improvements while supporting a collabor...
4 weeks ago
Director, Services- West Region
$173K - $216K *
Drive operational excellence by leading a diverse team focused on enhancing system reliability and availability through effective processes, project support, and proactive risk mitigation...
Reposted 2 weeks ago
$110K - $130K *
Lead the execution of complex client programs, ensuring timely delivery and budget adherence. Collaborate with cross-functional teams to drive accountability and clarity, while proactively managing ri...
4 days ago
$90K - $100K *
Join a dynamic team as a Senior Program Manager, driving client success and fostering relationships through strategic marketing solutions. Collaborate cross-functionally to execute impactful digital a...
4 weeks ago
$135K - $160K *
Join a team of expert engineers to innovate a Kubernetes resource management platform, enhancing DevOps productivity and addressing complex engineering problems in a dynamic environment...
Reposted 2 weeks ago
$142K - $229K *
Play a key role in driving customer success by managing a high-performing team, developing scalable strategies, and ensuring value realization for the Mid-Market Scale segment, all while enhancing cus...
Reposted 3 weeks ago
$150K - $180K *
Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...
2 weeks ago
$190K - $220K *
Join a team that's driving innovative therapies in neuroscience. Lead the strategic scientific narrative for key development programs while collaborating across functions to enhance clarity and impact...
4 weeks ago
Senior Staff Machine Learning Engineer, ML Understanding
$266K - $372K *
Optimize user personalization strategies by leading advanced ML user modeling initiatives. Shape cohesive user representation frameworks for improved engagement across Reddit's platforms, leveraging c...
3 weeks ago
What does a Director of Data Science do?
A Director of Data Science leads data science strategy and teams, oversees analytics and machine learning initiatives, and works with business and technical partners to deliver measurable outcomes.
What qualifications are typically required for Director, Data Science jobs?
Requirements vary, but employers often look for experience in data science or machine learning, a record of leading teams, strong communication skills, and the ability to align technical projects with business priorities. Some roles may request an advanced degree or expertise in a particular industry.
What industries hire Directors of Data Science?
Organizations in technology, finance, healthcare, retail, media, and many other data-rich industries hire data science leaders. The focus of each role depends on the employer's products, customers, and data needs.
How much do Director, Data Science jobs pay?
Compensation depends on factors such as location, industry, company size, and experience. Ladders focuses on vetted professional jobs paying $100,000 or more; review each listing for its stated compensation and details.
Where can I find Director, Data Science jobs paying $100,000 or more?
You can explore Director, Data Science opportunities on Ladders, where listings focus on professional roles with salaries of $100,000 or more.