Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Creative Growth Hacker (Paid, Social, Organic)
$100K - $120K *
Champion the growth of our AI-driven platform by designing automated workflows, optimizing paid acquisition, and driving organic growth through innovative strategies and creative campaigns across mult...
Yesterday
$110K - $130K *
Drive new logo acquisition and expansion revenue in key accounts, managing full-cycle sales from opportunity to contract. Collaborate with technical teams to build ROI models and ensure accurate forec...
Today
Cloud Platform Engineer (PaaS)
$155K - $165K *
Explore innovative solutions as a Hybrid Cloud Platform Engineer, collaborating with Agile teams to enhance a mission-critical PaaS for the Intelligence Community, ensuring secure deployment of applic...
4 weeks ago
Growth Marketing Manager, AI & Paid Programs
$110K - $130K *
Innovate demand generation strategies by managing paid media, automating workflows, and leveraging AI tools. Collaborate with teams to enhance pipeline efficiency and drive measurable results through...
5 days ago
Senior Test Automation Engineer
$120K - $145K *
Drive quality assurance excellence as a Senior Test Automation Engineer, leading automation strategy and ensuring robust testing practices across product domains to enhance reliability and performance...
Today
$76K - $120K *
Take ownership of critical operational pipelines as a Research Statistician, executing analyses and improving processes to ensure the SAT Suite runs smoothly. Collaborate with cross-functional teams t...
2 weeks ago
$110K - $130K *
Unlock insights by developing and maintaining Power BI dashboards that drive strategic decision-making. Collaborate with stakeholders and data teams to transform raw data into impactful visualizations...
Reposted today
$90K - $110K *
Elevate your career by owning key aspects of month-end close while optimizing AI-driven accounting operations. Collaborate with finance teams to enhance processes and support financial reporting in a...
1 week ago
$92K - $115K *
Unlock potential by leading requirements documentation for software projects. Collaborate with stakeholders and technical teams to ensure successful delivery throughout the project lifecycle, while su...
2 weeks ago
Team Lead- AI Enablement (Research)
$100K - $125K *
Champion innovation by integrating AI tools into workflows, enhancing research and consulting capabilities. Collaborate across teams to develop AI products, drive adoption, and foster a culture of con...
1 week ago
$152K - $190K *
Drive the future of data analytics by leading a dynamic team to enhance enterprise data strategies, governance, and insights that align with business objectives and foster innovation across the organi...
4 days ago
$220K - $250K *
Shape customer success by leading technical sales engagements, driving evaluations, and delivering tailored solutions. Collaborate with teams to ensure seamless deployment and integration, while build...
1 week ago
Project Environmental Scientist
$79K - $153K *
Unlock your potential as a Senior Environmental Due Diligence Professional, leading EDD projects and managing client relationships. Collaborate with a skilled team to deliver high-quality Phase I ESAs...
3 weeks ago
Senior Software Engineer (Capture)
$130K - $170K *
Accelerate progress at the forefront of real-time media ingestion, designing and operating distributed services that enhance communication data processing for analytics and security. Lead projects and...
3 weeks ago
Business Intelligence Solution Developer
$90K - $110K *
Champion data integrity and reporting readiness by managing data ingestion, ensuring quality, and collaborating across teams to support healthcare marketing analytics and decision-making processes...
Yesterday
Senior Entity Resolution Engineer
$160K - $195K *
Unlock your potential by building advanced entity matching solutions. Collaborate with a dedicated team to transform complex data into actionable insights, ensuring transparency and accuracy in every...
Reposted yesterday
$180K - $212K *
Drive growth through innovative demand generation strategies, leveraging data and analytics to enhance pipeline performance. Collaborate with cross-functional teams to optimize marketing efforts and l...
1 week ago
Lead Engineer Automation Quality
$105K - $149K *
Transform the future of automation by leading the development of innovative testing strategies and frameworks. Collaborate with teams to ensure high-quality deliverables through effective automation p...
Reposted yesterday
Senior Director, Data Architecture
$150K - $180K *
Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...
3 weeks ago
Staff Developer Platform Engineer
$183K - $200K *
Transform the Developer Platform by enhancing infrastructure and deployment processes. Collaborate with teams to ensure safe, efficient product delivery while driving adoption of innovative tooling an...
2 weeks ago
GIS Software Quality Assurance Engineer
$95K - $120K *
Champion quality assurance in GIS software by developing test plans, validating data, and ensuring reliability for Army geospatial applications. Collaborate with experts to enhance automated testing p...
2 weeks ago
Applied AI Health Data System Engineer-Senior Manager
$124K - $280K *
Unlock potential by leading AI and ML solutions in healthcare, driving innovation and operational efficiency. Collaborate with diverse teams to translate complex challenges into impactful outcomes thr...
Reposted 2 weeks ago
Senior Frontend Engineer, Ads Formats
$190K - $267K *
Drive impactful ad experiences by leveraging your frontend expertise in JavaScript and TypeScript. Collaborate with cross-functional teams to enhance user engagement and optimize ad performance across...
5 days ago
$110K - $130K *
Develop reliable backend systems and platforms that empower engineers. Own capabilities from design to production, enhance performance, and collaborate across teams to improve developer experience and...
Today
$120K - $145K *
Contribute to the development of a robust Kubernetes control plane, enhancing multi-cloud infrastructure and driving scalable architecture for enterprise-grade cloud services...
4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.