Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Principal Creative Intelligence Analyst
$110K - $120K *
Transform creative performance analysis by owning insights and recommendations for high-stakes accounts. Collaborate across teams to enhance workflows and drive impactful results in a fully remote env...
Today
Senior Machine learning Engineer
$162K - $258K *
Drive the design and implementation of cutting-edge GenAI solutions, leading the development of LLM capabilities and ML pipelines to enhance insurance workflows and deliver impactful outcomes for cust...
1 week ago
$110K - $130K *
Optimize marketing workflows by developing AI tools that enhance productivity across teams. Collaborate closely with stakeholders to build, maintain, and support innovative solutions that drive effici...
1 week ago
$90K - $110K *
Shape the future of consumer lending by analyzing credit risk and performance data to drive strategic insights for financial institutions, optimizing their underwriting processes and enhancing portfol...
Reposted 3 weeks ago
$130K - $155K *
Drive product growth through data analysis and experimentation, collaborating with cross-functional teams to enhance user adoption and engagement. Utilize statistical methods to illuminate user journe...
3 weeks ago
$96K *
Join a dynamic Finance team as a Financial Analyst, focusing on sales commissions and SaaS metrics. Collaborate across departments to ensure accurate financial reporting and drive insights that suppor...
2 weeks ago
$133K - $262K *
Unlock potential by developing AI-driven solutions that enhance business processes and integrate with enterprise systems. Collaborate with clients and teams to shape the future of finance and accounti...
Today
Principal Analytics Consultant (Sigma)
$125K - $150K *
Engineer transformative Sigma analytics solutions, leading complex projects that unlock business insights for clients. Collaborate closely with stakeholders to build actionable data-driven products, e...
Reposted 2 weeks ago
$80K - $95K *
Drive the future of finance data analysis by ensuring accuracy and usability of financial data. Collaborate with finance and data teams to enhance reporting processes and validate data integrity for i...
1 week ago
$140K - $270K *
Lead the charge in transforming healthcare workflows with AI solutions, optimizing performance, and collaborating across teams to create scalable systems that enhance clinical and revenue outcomes...
3 weeks ago
Senior Technical Consultant - Data & Analytics
$160K - $200K *
Lead the charge in designing and implementing scalable data solutions, orchestrating pipelines, and supporting advanced analytics in cloud environments. Collaborate with teams to deliver robust data a...
3 weeks ago
Senior Software Engineer, Biggy Engineering
$187K - $220K *
Unlock potential by designing and building AI-powered solutions to enhance enterprise IT operations, collaborating directly with customers and driving impactful product features across backend and aut...
Reposted 2 days ago
Marketing Analytics Director | United States | Remote
$178K - $214K *
Pioneer data-driven growth by architecting a marketing analytics ecosystem, leveraging advanced data science and AI to enhance strategy execution and optimize performance across the marketing funnel w...
Reposted 4 weeks ago
Analytics & AI Account Executive, Sales
$110K - $130K *
Elevate your career by partnering with sales teams to drive analytics and AI revenue. Leverage your expertise to accelerate deal closure, generate new opportunities, and empower field teams with strat...
Today
Senior Business Intelligence Analyst
$110K - $130K *
Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...
3 weeks ago
$125K - $150K *
Lead the charge in transforming innovative ideas into impactful AI-driven solutions for public health and medical research. Collaborate with diverse teams to develop MVPs that enhance scientific disco...
1 week ago
$80K - $95K *
Analyze labor market data and audience behaviors to develop actionable insights that enhance recruitment marketing strategies. Collaborate with cross-functional teams to create data-driven audience pe...
5 days ago
$147K - $274K *
Empower innovation by leading applied AI research initiatives that shape product features. Collaborate with cross-functional teams to translate complex problems into impactful AI solutions, mentoring...
1 week ago
Staff Machine Learning Engineer, Content Visual AI
$189K - $389K *
Tackle high-impact machine learning initiatives by leading a team to develop scalable content understanding systems, driving technical direction, and collaborating across domains to enhance user exper...
3 weeks ago
$190K - $267K *
Shape the future of app advertising by enhancing backend systems for conversion signals. Drive MMP integrations, SKAN processing, and App CAPI to ensure reliable app installs and in-app events for adv...
1 week ago
$95K - $115K *
Unlock potential by driving data-driven insights to enhance revenue and operational performance. Collaborate with cross-functional teams to transform complex data into actionable recommendations that...
Reposted 1 week ago
$125K - $144K *
Optimize our data platform by owning end-to-end data engineering projects, leveraging AI coding agents, and ensuring data quality. Collaborate with cross-functional teams to deliver reliable, maintain...
6 days ago
$110K - $130K *
Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...
1 week ago
Senior Engineer (Azure, Terraform, Kubernetes)
$150K - $175K *
Lead the charge in architecting and managing robust cloud platforms, driving modernization efforts, and automating infrastructure solutions for large-scale enterprises. Collaborate with top engineers...
1 week ago
Senior Engineer (AWS, Azure, Terraform, Kubernetes)
$150K - $175K *
Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.