Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$103K - $138K *
Unlock potential by designing and automating secure, scalable AWS cloud platforms. Collaborate with cross-functional teams to enhance infrastructure reliability and streamline software delivery throug...
3 weeks ago
Solution Architect, Forward Deployed AI
$135K - $160K *
Transform AI pilots into secure, reliable production systems by designing innovative solutions and collaborating with cross-functional teams to ensure responsible enterprise adoption of AI technologie...
Today
People Technology Analyst - Workday
$95K - $160K *
Elevate People Technology by optimizing systems and processes, ensuring data integrity, and enhancing user experiences. Collaborate with cross-functional teams to drive efficiency and support a fast-p...
3 weeks ago
Lead Technical Analyst - Real Estate Applications (Yardi)
$121K - $167K *
Lead the evolution of real estate applications by designing and implementing innovative technology solutions, enhancing system reliability, and driving proactive support across Yardi platforms and int...
2 weeks ago
$79K - $102K *
Champion customer success by guiding Mid-Market clients through the deployment and adoption of IoT solutions, ensuring they maximize value from our technology while building strong relationships acros...
Reposted 1 week ago
$88K - $214K *
Shape enterprise data architectures by leveraging your expertise in Databricks and modern cloud platforms. Collaborate with clients to design scalable solutions that drive analytics, AI/ML, and data g...
3 weeks ago
$100K - $185K *
Elevate the legal landscape by leveraging AI to transform workflows. Collaborate with law firms to design and implement innovative solutions, ensuring successful adoption of advanced legal technologie...
2 weeks ago
Business Intelligence Engineer III - 175327 - 176952
$120K - $140K *
Unlock potential by designing and optimizing Power BI solutions, collaborating with stakeholders to enhance reporting and analytics capabilities in a fully remote environment. Drive data accuracy and...
1 week ago
$98K - $163K *
Analyze and maintain program data to enhance recruitment and onboarding processes. Collaborate with stakeholders to ensure accurate reporting and insights that drive decision-making and improve partic...
2 days ago
Senior Manager, Machine Learning Engineering
$230K - $290K *
Lead the charge in optimizing ad performance through innovative algorithms and machine learning. Collaborate with cross-functional teams to enhance advertising effectiveness and drive business success...
3 days ago
$176K - $230K *
Drive impactful healthcare innovations by leveraging data science to enhance patient outcomes. Lead projects from concept to business impact, collaborating with stakeholders and mentoring peers to del...
Reposted today
Project Manager- Professional Services
$110K - $130K *
Lead end-to-end client engagements for complex AI and digital projects, managing multiple implementations while ensuring timely delivery and exceeding client expectations. Collaborate with cross-funct...
Reposted today
Data Center Substation, Protection & Automation Engineer
$320K - $405K *
Engineer cutting-edge protection and automation systems for high-voltage substations, ensuring reliable power distribution and integration across our infrastructure portfolio. Collaborate with teams t...
4 days ago
$73K - $102K *
Unlock potential by leading the development of LLM-powered applications and agentic systems. Collaborate across teams to design, implement, and maintain innovative software solutions, ensuring high qu...
3 weeks ago
$80K - $95K *
Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...
3 weeks ago
$145K - $175K *
Champion the integration of AI-powered API services, ensuring reliability and scalability while bridging traditional systems with modern language models. Drive innovation in backend workflows and coll...
2 weeks ago
Solutions Lead, Consulting/Banking
$170K - $200K *
Pioneer innovative solutions by leading client engagements with top firms. Drive discovery, connect needs to data insights, and collaborate across teams to deliver impactful results in a dynamic, remo...
2 weeks ago
AI & GenAI Data Scientist - Manager
$99K - $232K *
Lead the design and implementation of AI solutions, transforming data into actionable insights. Mentor teams, enhance data strategies, and drive innovation in technology consulting for impactful busin...
Reposted 2 weeks ago
AI & GenAI Data Scientist - Manager
$99K - $232K *
Lead the charge in delivering transformative AI solutions, guiding a team of data scientists to generate actionable insights that drive business growth, while mentoring talent and managing complex dat...
Reposted 2 weeks ago
$115K - $159K *
Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...
6 days ago
$120K - $145K *
Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...
2 weeks ago
Methodology Engineer (Silicon)
$120K - $145K *
Transform engineering processes by developing verification tools, dashboards, and shared infrastructure. Collaborate with teams to enhance quality checks and streamline workflows, ensuring efficient s...
3 weeks ago
Director of Analytics, Revenue Growth
$135K - $160K *
Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...
4 days ago
$140K - $200K *
Empower mission-critical federal systems by leading the design and automation of secure cloud platforms. Drive reliability, mentor engineers, and set technical direction in a collaborative environment...
4 days ago
Lead Director - Digital Product (Causal Analytics)
$144K - $288K *
Empower product innovation by leading analytics development, defining strategies, and collaborating with cross-functional teams to enhance patient care and drive impactful solutions in a dynamic envir...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.