Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sales Incentive Compensation Data Analyst
$73K - $109K *
Take ownership of data governance and reporting for sales incentive programs, ensuring accurate performance data translates into meaningful payouts. Collaborate with teams to drive sales behavior thro...
4 days ago
$90K - $110K *
Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...
6 days ago
$130K - $140K *
Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...
1 week ago
$95K - $115K *
Unlock the potential of implementation science as a Senior Program Analyst, driving quality improvement and program evaluation initiatives. Manage processes, databases, and reporting to enhance projec...
2 weeks ago
$125K - $145K *
Shape the future of sports media by leveraging data science to enhance user experience, optimize workflows, and develop predictive models that drive engagement and subscriptions. Collaborate with cros...
4 weeks ago
Enterprise AI Transformation Consultant
$70K - $196K *
Unlock potential by leveraging your software engineering expertise to build innovative AI solutions. Collaborate on enterprise transformation projects, enhancing systems with cutting-edge technologies...
1 week ago
Associate Director, Product (Data)
$165K - $175K *
Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...
4 weeks ago
$110K - $130K *
Elevate enterprise AI initiatives by partnering with clients to drive strategic solutions. Leverage your expertise to engage senior leaders, design impactful demos, and accelerate deal cycles, ensurin...
3 days ago
$80K - $104K *
Optimize ETL processes by designing and maintaining robust data integration solutions. Collaborate with cross-functional teams to ensure data accuracy and performance, while mentoring junior developer...
5 days ago
$125K - $150K *
Transform enterprise data architecture through expert Azure platform engineering, enhancing reliability, governance, and cost-efficiency while collaborating with cross-functional teams to optimize dat...
Reposted 6 days ago
Senior Manager, Engineering Recruiting
$110K - $130K *
Lead the charge in engineering recruiting by shaping hiring strategies, developing a high-performing team, and enhancing scalable processes to support growth while personally managing senior leadershi...
2 weeks ago
Senior Project Manager - Data Center
$110K - $130K *
Langan is seeking a Senior Site/Civil Project Manager specializing in Data Centers and Critical Facilities to lead design, permitting, and client management efforts for land development projects. This...
Reposted 2 days ago
Senior Project Manager - Data Center
$110K - $130K *
Drive exceptional land development projects in data centers. Lead multi-discipline teams, manage client relationships, and ensure successful project execution from concept through completion, empoweri...
Reposted 2 days ago
$113K - $191K *
Empower innovation in safety technology by developing AI-driven solutions that enhance customer experiences and operational efficiency. Collaborate across teams to deliver scalable, impactful products...
Reposted today
$117K - $157K *
Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...
2 weeks ago
$150K - $170K *
Join a team that's transforming drug development through data science. Leverage your expertise to build predictive models and analytics, driving process improvements and technology transfer in a colla...
3 weeks ago
Senior Business Applications Engineer
$150K - $200K *
Lead the charge in transforming business challenges into innovative solutions by leveraging your expertise in automation and integration. Collaborate across teams to enhance operational efficiency and...
1 week ago
Senior Director, Analytical Development
$230K - $280K *
Champion analytical development by leading strategy and execution for pipeline products. Drive compliance and quality control while building a high-performing team in a dynamic environment focused on...
Today
Senior Scientist - Analytical Chemist
$88K - $105K *
Empower innovation in analytical chemistry by developing LC-MS methods, mentoring junior scientists, and enhancing lab operations. Drive project success through method validation and troubleshooting i...
4 days ago
Software Product Management Pre Sales Senior Manager - Marketing Analytics Software
$122K - $271K *
Transform the pre-sales landscape by delivering impactful software demos, guiding clients through complex sales cycles, and developing reusable assets to enhance engagement and conversion rates across...
Yesterday
Sr Software Engineer, Cribl AI
$185K - $215K *
Discover the opportunity to integrate cutting-edge AI technologies into innovative observability solutions, collaborating with a skilled team to deliver exceptional customer experiences and drive mean...
Reposted today
Senior Financial Analyst, FP&A (R&D)
$111K - $167K *
Transform financial operations by driving monthly close processes, managing forecasts, and leveraging AI for process improvements while serving as a key business partner to leadership to enhance strat...
Reposted 1 week ago
Principal Software Engineer - Marketing Technology
$155K - $197K *
Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...
5 days ago
$170K - $185K *
Champion the development of scalable data platforms, leading cross-functional initiatives and enhancing AI-assisted analytics. Collaborate with teams to drive technical direction and improve system pe...
2 weeks ago
Customer Success Operations Analyst
$120K - $130K *
Drive the transformation of customer data into automated reporting and AI tools, enhancing customer health tracking and executive visibility. Collaborate across teams to streamline workflows and ensur...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.