Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K - $120K *
Join a dynamic team as a System Engineer, specializing in Linux systems and automation. You'll lead the design and maintenance of provisioning workflows, configuration management, and Linux networking...
Yesterday
Sr. Manager, People Technology & Analytics
$132K - $194K *
Unlock potential by leading the strategy and evolution of People technology and analytics. Drive data governance and insights to enhance decision-making and operational efficiency, while partnering wi...
Reposted today
Data Engineering, Management & Governance Manager
$94K - $293K *
Champion the design and delivery of strategic AI insights platforms, ensuring data integrity and business value realization through advanced data architecture and governance practices across diverse e...
4 weeks ago
Community Engagement Manager, Data Centers (New York)
$265K - $295K *
Shape community engagement strategies to foster trust and collaboration with local stakeholders, ensuring Anthropic's infrastructure projects benefit the communities we serve while navigating complex...
2 weeks ago
Managed Services - Data Analytics & Business Intelligence - Manager
$99K - $232K *
Drive impactful data analytics and business intelligence initiatives, leading teams to transform insights into operational excellence while ensuring quality and client satisfaction in managed services...
Today
Managed Services - Data Analytics & Business Intelligence - Manager
$99K - $232K *
Lead analytics initiatives to transform data into actionable insights, guiding teams and enhancing operational performance through innovative reporting solutions and strategic client engagement in man...
Today
Community Engagement Manager, Data Centers (Louisiana)
$265K - $295K *
Drive community engagement and build trusted relationships with local stakeholders to ensure Anthropic's infrastructure projects are positively received and beneficial to the communities in Louisiana...
2 weeks ago
Enterprise Architect - Data & Employee Systems (Databricks)
$150K - $170K *
Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...
1 week ago
$138K - $194K *
Build and maintain secure backend systems for Public Sector customers, ensuring high engineering standards while collaborating with cross-functional teams to deliver innovative solutions that meet reg...
Reposted 4 days ago
Account Executive, Audit Manager
$100K - $170K *
Champion the growth of Audit Manager by driving sales in the healthcare sector. Leverage your expertise in medical billing and coding to engage revenue cycle leaders, manage the sales pipeline, and de...
1 week ago
$121K - $182K *
Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...
5 days ago
$90K - $137K *
Lead the charge in cloud migration by managing infrastructure engineering tasks, executing migrations to Azure and AWS, and ensuring operational readiness for applications and services in a dynamic, r...
5 days ago
$135K - $145K *
Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...
Reposted 6 days ago
$100K - $150K *
Shape the future of AI solutions by leading cross-functional teams to enhance project delivery and business operations through innovative automation and data-driven strategies, ensuring sustainable an...
Today
Engineering Manager, Admin Experience
$225K - $265K *
Shape the future of secure administration by leading a dynamic engineering team focused on backend services, user access, and account management. Drive innovation while ensuring operational excellence...
4 days ago
Analytical Chemistry Staff Scientist
$80K - $95K *
Join a team that's dedicated to delivering high-quality research in a fast-paced environment. Collaborate with diverse scientists to conduct advanced analytical chemistry projects while ensuring compl...
Yesterday
Account Executive, Enterprise Suite - Financial Services
$124K - $171K *
Accelerate sales growth by managing and qualifying strategic Enterprise Intelligence opportunities. Collaborate with cross-functional teams, ensuring comprehensive engagement and communication to opti...
Reposted 1 week ago
$141K - $196K *
Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...
5 days ago
$90K - $110K *
Join a dynamic team to enhance financial management practices and support critical operations. Collaborate across levels to drive process improvements and deliver impactful financial insights in a fas...
2 weeks ago
Medical Analytics Impact & Outcomes Data Analyst
$124K - $207K *
Drive impactful analytics in Medical Affairs by developing KPIs, analyzing data trends, and collaborating with cross-functional teams to enhance decision-making and resource allocation for optimal bus...
2 days ago
$80K - $95K *
Empower clients by managing energy procurement operations, leading RFP processes, and delivering market insights. Collaborate with suppliers and customers to optimize strategies in deregulated electri...
2 weeks ago
$110K - $130K *
Champion AI deployment by designing and implementing innovative solutions across multiple platforms. Collaborate with teams to enhance customer experiences while ensuring data governance and security...
3 weeks ago
$135K - $155K *
Drive data science initiatives to transform clinical and real-world data into actionable insights, supporting cross-functional teams in medical device research and development. Collaborate effectively...
2 weeks ago
Staff Machine Learning Engineer
$218K - $256K *
Shape the future of customer engagement by leading the design and delivery of innovative ML systems. Collaborate with cross-functional teams to enhance automation, safety, and customer experience thro...
3 weeks ago
$90K - $110K *
Unlock potential by leading the functional support and improvement of business systems for Legal, Procurement, Safety, and Environmental teams, ensuring effective use and resolution of issues while en...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.