Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Engineering Manager, Data Streaming
$225K - $265K *
Accelerate progress at a mission-critical team, leading Data Streaming to enhance data ingestion pipelines. Build a skilled team, ensure pipeline reliability, and collaborate cross-functionally to sup...
1 week ago
Insights Lead, Brand & Consumer Analytics
$122K - $292K *
Transform data into actionable insights, leading analytics for Brand and Consumer initiatives. Collaborate with stakeholders to drive strategic recommendations and enhance business performance through...
Yesterday
Insights Lead, Brand & Consumer Analytics
$132K - $292K *
Lead advanced analytics initiatives to transform data into actionable insights, driving strategic decisions across Brand and Consumer sectors. Collaborate with stakeholders to enhance business perform...
Yesterday
Staff Data Scientist - Credit and Lending ML
$166K - $298K *
Join a team that's redefining small business lending through advanced ML models. You'll build and deploy critical models, partner with cross-functional teams, and set the technical standards for machi...
Today
Data Analyst, Clinical Data Effectiveness
$95K - $115K *
Analyze and optimize the clinical data lifecycle, ensuring data completeness and integrity. Collaborate cross-functionally to enhance clinical data flows and vendor strategies, driving quality improve...
Reposted 2 days ago
$90K - $110K *
Partner with us to design, build, and maintain data pipelines, ensuring reliable access to structured data for analytics, reporting, and emerging AI/ML applications across finance, HR, and operational...
Reposted 2 weeks ago
$172K - $205K *
Transform data into actionable insights to optimize the insurance business. Collaborate with cross-functional teams to enhance customer experience and drive revenue growth through advanced analytics a...
2 days ago
Senior Applied Scientist II, Ads Optimization
$240K - $253K *
Pioneer innovation in real-time bid optimization systems, driving advertising performance by turning complex mathematical insights into robust production code. Lead cross-functional initiatives to max...
Reposted 6 days ago
Senior Machine Learning Engineer, ML Infrastructure- Online
$210K - $273K *
Drive the evolution of a robust online ML inference platform, enhancing model deployment, performance, and safety in high-traffic environments by collaborating with cross-functional teams and spearhea...
Reposted 5 days ago
Staff Machine Learning Engineer, Retrieval & Targeting
$230K - $322K *
Grow your career with a leading ML team focused on enhancing ad retrieval systems. Drive technical direction, develop innovative models, and collaborate across teams to optimize user experience and ad...
1 week ago
AI Deployment Engineer/Manager
$80K - $95K *
Champion the deployment of cutting-edge AI systems in diverse environments. Collaborate with teams to ensure seamless installation and operation of hardware and software, while providing exceptional c...
1 week ago
$150K - $190K *
Unlock potential by designing scalable data models and ensuring data quality. Collaborate with cross-functional teams to translate business needs into technical solutions, driving analytics excellence...
1 week ago
Senior Data Scientist II, Monetization
$183K - $216K *
Take ownership of the scientific and product roadmap for monetization, leading audience creation and measurement methodologies. Collaborate with cross-functional teams to drive product strategy and in...
3 weeks ago
Lead Consultant, AI & Analytics
$120K - $145K *
Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...
2 weeks ago
Sr. Data Scientist, Forward-Deployed
$168K - $230K *
Lead impactful data science initiatives by measuring engagement outcomes and building customer models. Collaborate with senior data scientists to drive analytics that directly influence business succe...
Reposted yesterday
Senior Data Scientist II, Core & Agentic Automation
$183K - $216K *
Unlock your potential by leading data science initiatives that drive impactful decision-making and enhance analytical frameworks across teams, ensuring rigorous performance standards and scalable self...
2 weeks ago
$120K - $145K *
Join a team that's pioneering the deployment of scalable AI systems, focusing on building robust APIs, optimizing infrastructure, and ensuring reliable operations in a dynamic environment. Drive innov...
2 weeks ago
Senior Machine Learning Systems Engineer - Search
$150K - $180K *
Join a team that's at the forefront of machine learning and search innovation. Collaborate with cross-functional teams to develop scalable ML systems that enhance user experiences and drive impactful...
4 weeks ago
$104K - $130K *
Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...
Reposted today
Staff Machine Learning Engineer
$156K - $275K *
Transform machine learning infrastructure by deploying scalable models, building pipelines, and ensuring model health across product and marketing workflows. Collaborate with data scientists and engin...
Today
$130K - $155K *
Champion innovative data solutions by designing and maintaining robust data pipelines across Azure and Microsoft Fabric, ensuring high-quality data delivery and governance while leading engineering in...
2 days ago
$130K - $155K *
Join a team that's redefining data infrastructure by owning and optimizing our data pipelines, warehouse, and modeling layers. Collaborate with cross-functional teams to ensure data integrity and driv...
Reposted 2 weeks ago
$120K - $145K *
Lead the charge in developing innovative AI software solutions, enhancing system performance, and collaborating with teams to align with IT roadmaps. Drive improvements through analysis and ensure sea...
2 days ago
Data Analyst (Healthcare Data Analytics)
$80K - $115K *
Analyze and enhance client data reporting, driving insights and trends to support customer satisfaction and business growth. Collaborate with cross-functional teams to ensure data integrity and delive...
4 weeks ago
Senior AI Transformation Analyst
$90K - $110K *
Drive AI transformation by mapping current processes and designing future-state models across G&A functions. Collaborate with stakeholders to identify automation opportunities and enhance operational...
Reposted yesterday
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.