Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $175K *

Lead the charge in architecting and managing robust cloud platforms, driving modernization efforts, and automating infrastructure solutions for large-scale enterprises. Collaborate with top engineers...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $175K *

Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$142K - $186K *

Deliver trusted, governed product data by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure data quality and compliance, empowering stakeholders with self-servi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$159K - $188K *

Unlock potential by leveraging data to drive product decisions and enhance user engagement. Collaborate across teams to design experiments, develop predictive models, and influence product strategies...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $100K *

Transform your career with this client-facing role, leveraging your expertise in analytics tools like Google Analytics and Tag Manager to deliver strategic solutions and enhance data-driven decision-m...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Media

$180K - $220K *

Help us optimize healthcare data processes by designing and managing robust data pipelines. You'll integrate legacy systems into a unified platform, ensuring data quality and operational efficiency in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$108K - $157K *

Optimize data-driven strategies by transforming raw analytics into actionable insights. Collaborate with cross-functional teams to enhance marketplace dynamics and drive measurable business outcomes i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$162K - $170K *

Drive advanced machine learning solutions as a key contributor to our perception team, focusing on deep learning and computer vision to enhance robotics technology and bring innovative models from ide...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$79K - $105K *

Develop and implement strategies to manage financial and compliance risks in a dynamic payments environment. Analyze transaction patterns to identify risks and collaborate with teams to enhance fraud...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $92K *

Unlock insights as you support senior analysts in corporate bond and bank loan research. Collaborate on financial models, enhance credit processes, and develop your analytical skills in a dynamic inve...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $270K *

Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that's redefining data engineering by building scalable data systems and interfaces. You'll design data models, develop real-world use cases, and ensure reliable data flows, all while writ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$104K - $174K *

Unlock your potential by developing and implementing advanced analytics and AI solutions. Collaborate with cross-functional teams to translate complex data into actionable insights, driving business a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$138K - $165K *

Shape the future of consumer applications by leading machine learning and Generative AI initiatives. Build robust data pipelines, develop and deploy models, and drive business impact through experimen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$199K - $334K *

Champion the architecture and engineering of agent memory systems, leading the development of context-driven AI agents. Drive innovation and technical direction while collaborating across teams to enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$204K - $216K *

Unlock potential by designing robust data models that empower AI systems. You will ensure data coherence and quality, bridging knowledge representation and machine learning across diverse communities...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $270K *

Unlock potential by designing and deploying scalable AI systems that transform healthcare workflows. Collaborate with cross-functional teams to solve complex business challenges and drive measurable o...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$159K - $188K *

Transform audience and measurement products by independently owning the full lifecycle, from problem framing to delivery. Collaborate with cross-functional teams to enhance data-driven advertising sol...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Technical Services

$136K - $239K *

Unlock your potential by leading statistical programming efforts in clinical trials. Collaborate with cross-functional teams to analyze and report clinical data, ensuring compliance with industry stan...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by designing and implementing innovative knowledge graph solutions for healthcare data. Collaborate with cross-functional teams to translate complex requirements into scalable, produc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive your career with a dynamic role focused on data analysis and visualization across digital marketing channels. Collaborate with teams to create impactful dashboards and predictive models that enh...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to transforming healthcare data into actionable insights. This role involves analyzing complex datasets, collaborating with stakeholders, and delivering data-driven recomm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Accelerate progress at the intersection of marketing and data analytics. As a key player, you'll build reporting functions, define KPIs, and drive insights that empower teams across the organization t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.