Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $185K *

Elevate the legal landscape by leveraging AI to transform workflows. Collaborate with law firms to design and implement innovative solutions, ensuring successful adoption of advanced legal technologie...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$80K - $100K *

Empower client success by managing portfolios, ensuring operational efficiency, and supporting Client Managers. Develop essential skills in data accuracy and communication while contributing to high c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $140K *

Unlock potential by designing and optimizing Power BI solutions, collaborating with stakeholders to enhance reporting and analytics capabilities in a fully remote environment. Drive data accuracy and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$90K - $110K *

Join us to enhance automation control systems for industrial processes. Leverage your engineering expertise to troubleshoot, optimize, and implement solutions that improve reliability and performance...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$98K - $163K *

Analyze and maintain program data to enhance recruitment and onboarding processes. Collaborate with stakeholders to ensure accurate reporting and insights that drive decision-making and improve partic...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$230K - $290K *

Lead the charge in optimizing ad performance through innovative algorithms and machine learning. Collaborate with cross-functional teams to enhance advertising effectiveness and drive business success...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$176K - $230K *

Drive impactful healthcare innovations by leveraging data science to enhance patient outcomes. Lead projects from concept to business impact, collaborating with stakeholders and mentoring peers to del...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead end-to-end client engagements for complex AI and digital projects, managing multiple implementations while ensuring timely delivery and exceeding client expectations. Collaborate with cross-funct...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$320K - $405K *

Engineer cutting-edge protection and automation systems for high-voltage substations, ensuring reliable power distribution and integration across our infrastructure portfolio. Collaborate with teams t...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$73K - $102K *

Unlock potential by leading the development of LLM-powered applications and agentic systems. Collaborate across teams to design, implement, and maintain innovative software solutions, ensuring high qu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$145K - $175K *

Champion the integration of AI-powered API services, ensuring reliability and scalability while bridging traditional systems with modern language models. Drive innovation in backend workflows and coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $200K *

Pioneer innovative solutions by leading client engagements with top firms. Drive discovery, connect needs to data insights, and collaborate across teams to deliver impactful results in a dynamic, remo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$99K - $232K *

Join a team that's transforming data into actionable insights by designing AI systems. As a Manager, you will lead projects, mentor talent, and drive the implementation of innovative solutions to enha...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$115K - $159K *

Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform engineering processes by developing verification tools, dashboards, and shared infrastructure. Collaborate with teams to enhance quality checks and streamline workflows, ensuring efficient s...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $200K *

Empower mission-critical federal systems by leading the design and automation of secure cloud platforms. Drive reliability, mentor engineers, and set technical direction in a collaborative environment...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $288K *

Empower product innovation by leading analytics development, defining strategies, and collaborating with cross-functional teams to enhance patient care and drive impactful solutions in a dynamic envir...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $220K *

Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Media

$100K - $140K *

Empower integration solutions by designing and maintaining critical connections across platforms, enhancing Quote-to-Cash processes and ensuring seamless data flow for thousands of merchants through i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$199K - $230K *

Drive innovation by deploying and optimizing cloud infrastructure across federal environments. Leverage your expertise in AWS, Kubernetes, and automation tools to enhance platform scalability and secu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform engine performance analysis by deploying advanced modeling techniques and optimizing workflows. Collaborate with engineers to enhance product development and drive innovation in engine engin...

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$80K - $100K *

Optimize data-driven strategies to enhance customer engagement and retention. Collaborate with operations to implement scalable solutions in a dynamic startup environment, making a significant impact...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.