Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
$100K - $120K *
Explore opportunities to partner with engineers and stakeholders, translating technical discussions into actionable deliverables while supporting CI/CD initiatives and repository governance with a foc...
4 weeks ago
Applications Scientist - NGS Design
$80K - $95K *
Join a team that's dedicated to providing expert technical support and custom NGS panel design, enhancing customer experiences and driving collaborative projects in the genomics industry while documen...
Yesterday
Associate Staff Engineer - INFOR M3 Technical Consultant
$100K - $120K *
Optimize your career as an Infor M3 Technical Consultant, leveraging 3-5 years of expertise in integrations and development. Collaborate with teams to design and support seamless enterprise solutions...
3 weeks ago
Lead Applied Scientist, NBA – Reinforcement Learning
$129K - $177K *
Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...
1 week ago
Customer Engagement Applications Engineer - Southern California - SPTS Division
$102K - $173K *
Join us to advance semiconductor technology by delivering innovative process solutions, collaborating with teams, and enhancing customer satisfaction in a dynamic, field-based role that drives impactf...
6 days ago
$135K - $160K *
Help us drive growth as an Enterprise Account Executive, engaging with top-tier clients to tackle fraud challenges using innovative solutions. Collaborate cross-functionally to shape strategies that e...
Today
Senior Software Engineer II, Applied AI
$125K - $150K *
Architect AI-driven solutions that automate workflows across teams, enhancing efficiency and productivity. Collaborate with diverse departments to design, deploy, and iterate on intelligent agents, sh...
2 weeks ago
Lead Machine Learning Engineer
$220K - $270K *
Join a team that's pushing the boundaries of machine learning in autonomous vehicles. Enhance driving capabilities, lead innovative teams, and drive commercial-scale solutions with cutting-edge techno...
Reposted 6 days ago
Senior Marketing Manager - Narrative and Launch
$135K - $165K *
Transform the marketing landscape by driving product launches, shaping narratives, and executing strategies in a dynamic environment. Collaborate closely with engineers to communicate complex technolo...
Reposted 2 days ago
Digital Adoption & Lifecycle Manager
$110K - $130K *
Empower customer success by designing and executing lifecycle programs that enhance adoption, retention, and expansion. Collaborate across teams to create impactful communications and leverage data-dr...
3 weeks ago
$80K - $95K *
Transform sales operations by leading deal desk activities, guiding reps on deal structuring, and driving data analysis for revenue forecasting. Collaborate with finance and sales leadership to ensure...
5 days ago
Lead Analyst Digital Accelerator
$96K - $135K *
Champion process automation and enhancements by leading investment initiatives, mentoring teams, and collaborating across departments to drive efficiency and continuous improvement in investment servi...
1 week ago
$171K - $180K *
Join a team that's dedicated to enhancing security through robust detection engineering. Develop detection logic, optimize processes, and collaborate across teams to elevate the security posture of a...
Reposted 2 days ago
Senior Engineering Consultant - Equity Due Diligence
$110K - $130K *
Unlock potential by leading complex commercial real estate due diligence projects. Collaborate with multidisciplinary teams to provide technical guidance and client leadership, ensuring high-quality d...
1 week ago
$95K - $115K *
Join a team that's redefining network solutions by designing, implementing, and supporting advanced LAN, WAN, and wireless systems. Collaborate with cross-functional leaders to enhance network strateg...
2 weeks ago
$140K - $165K *
Drive innovative fraud risk management solutions by leveraging advanced machine learning and data analytics. Collaborate with stakeholders to enhance model development and mentor junior data scientist...
2 weeks ago
$110K - $130K *
Innovate healthcare delivery by developing AI solutions that enhance operations and resident experiences. Collaborate with teams to automate processes and improve clinical decision-making in senior ca...
1 month ago
$119K - $179K *
Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...
4 weeks ago
Senior Software Engineer II - Agentic SDLC
$170K - $185K *
Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...
1 week ago
ServiceNow Business Data Analyst
$90K - $189K *
Elevate your career as a ServiceNow Business Analyst, bridging data analysis and IT modernization. Collaborate with stakeholders to optimize workflows and enhance performance outcomes through actionab...
2 weeks ago
Technical Success Manager- Central
$100K - $120K *
Elevate customer success by leveraging technical expertise and advocacy to drive adoption of cybersecurity solutions, ensuring measurable outcomes and risk reduction through strategic partnerships wit...
2 weeks ago
Lead Platform Engineer, AI and DevSecOps
$155K - $175K *
Empower engineering teams by leading the evolution of cloud, security, and AI operations. Drive platform reliability and DevSecOps practices while mentoring others to foster a collaborative, innovativ...
3 weeks ago
Senior Software Engineer, AV Analysis Platform
$224K - $356K *
Pioneer the development of advanced evaluation tools for Autonomous Vehicles, enhancing workflows and system performance. Collaborate with cross-functional teams to deliver scalable solutions that imp...
1 week ago
Senior Staff Forward Deployed Engineer
$152K - $205K *
Lead the charge in architecting AI-driven solutions for enterprise clients, transforming complex data governance challenges into actionable insights. Collaborate with stakeholders to shape product evo...
3 weeks ago
Senior Quantitative Researcher - CMMI Evaluations
$120K - $150K *
Unlock potential by leading complex evaluations in healthcare innovation. Collaborate with a diverse team to enhance Medicare and Medicaid services through rigorous research, technical expertise, and...
3 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.