Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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Sort By: Relevance

$100K - $120K *

Unlock potential by leveraging your expertise in data analysis and psychometrics to drive innovative assessment solutions. Collaborate with a dynamic team to enhance educational outcomes through advan...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$207K - $244K *

Shape the financial data landscape by leading analytics initiatives, ensuring accurate, timely reporting and compliance. Collaborate with cross-functional teams to build scalable data pipelines and ma...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $195K *

Innovate with us to develop and deploy cutting-edge AI solutions that enhance advertising measurement products. Collaborate across teams to drive impactful data-driven decisions and expand our capabil...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$185K - $260K *

Join Reddit's Ads team as a Machine Learning Engineer, where you will design, build, and deploy machine learning models to enhance ad ranking, bidding, and optimization. This hands-on role involves ta...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Media

$216K - $303K *

Discover an exciting opportunity to drive innovation in ad optimization and marketplace quality, creating impactful bidding and auction systems that enhance user experience and maximize advertiser suc...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Transform the renewable energy landscape by managing data portfolios, analyzing project performance, and enhancing financial reporting. Collaborate with cross-functional teams to drive strategic energ...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's building and scaling a data and analytics platform to enhance clinical AI performance. Collaborate with cross-functional teams to create actionable insights and drive improvements i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $170K *

Transform data into actionable insights by analyzing EV telematics and charging patterns. Collaborate across teams to enhance data quality and drive product innovation, shaping the future of electric...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $100K *

Unlock insights by analyzing customer and operational data to enhance business outcomes. Collaborate with cross-functional teams to develop dashboards and reports that drive strategic decisions and im...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $145K *

Elevate revenue and risk strategies by leveraging data insights to drive impactful business decisions. Collaborate across teams to optimize processes, influence product development, and enhance client...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K *

Engage in cutting-edge AI projects by developing and deploying NLP models. Collaborate with cross-functional teams to optimize performance and scalability, utilizing frameworks like PyTorch or TensorF...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Advance healthcare solutions by developing scalable ML systems, collaborating with cross-functional teams, and driving innovative AI methodologies to enhance patient outcomes and optimize operational...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Unlock potential by optimizing commercial processes through AI and analytics. Collaborate with teams to enhance efficiency, forecasting, and decision-making, driving impactful business outcomes across...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$171K - $269K *

Engineer cutting-edge machine learning algorithms and models, collaborating across teams to integrate AI functionalities into products. Drive innovation and ensure AI's transformative potential is rea...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$117K - $195K *

Transform data into actionable insights by leveraging advanced analytics and visualization techniques. Collaborate with a dynamic team to support federal clients through data mining, preparation, and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$72K - $100K *

Join our dynamic team as a Sr. Credit Analyst, owning the underwriting cycle from application review to decision-making. Leverage your analytical skills to enhance credit processes and contribute to a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $130K *

Unlock your potential by leading the design and delivery of enterprise analytics solutions. Collaborate with cross-functional teams to enhance data quality and reporting processes, driving impactful b...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Analyze and evaluate AI-generated chatbot responses to enhance accuracy and relevance. Collaborate with stakeholders to document requirements and deliver structured assessments that drive improvements...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Transform the evaluation of AI systems by analyzing chatbot responses, documenting requirements, and delivering structured assessments to enhance accuracy and effectiveness in business processes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$140K - $180K *

Transform cancer care by developing AI biomarkers through collaboration with ML scientists and clinical partners, enhancing model robustness and interpretability across diverse datasets to improve pat...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $149K *

Unlock potential by leading healthcare data analytics to enhance hospital quality performance and rankings. Collaborate with teams to design dashboards, mentor analysts, and present insights to execut...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$216K - $322K *

Shape the future of AI by leading ML projects from concept to production, collaborating with cross-functional teams to enhance recommendations, search, and messaging systems while driving measurable u...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$150K - $180K *

Design and optimize evaluation systems for AI agents, enhancing performance and quality through innovative metrics and benchmarks. Collaborate with cross-functional teams to ensure agents meet user ne...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $220K *

Drive the end-to-end ML and LLM lifecycle, optimizing AI workflows and automations. Collaborate with cross-functional teams to ensure scalable, reliable production of AI-driven solutions while impleme...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$94K - $293K *

Discover innovative data solutions by leading migration engagements, focusing on AI systems. Utilize advanced techniques for data lineage and evidence extraction to ensure robust data pipelines and pr...

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.