Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$90K - $110K *

Build and support AI tools and workflows, collaborating with stakeholders to create scalable solutions that integrate with enterprise platforms, ensuring reliability and security throughout the soluti...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$70K - $110K *

Unlock your potential by analyzing data and conducting audits to enhance compliance for innovative B2B and B2C platforms. Collaborate with cross-functional teams, apply critical thinking, and gain ins...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$84K - $126K *

Transform client engagement through data-driven insights and innovative CRM solutions. Lead a dynamic team to enhance client intelligence, streamline processes, and drive strategic marketing initiativ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$153K - $219K *

Innovate data science solutions to enhance global recognition programs, streamline workflows, and ensure data integrity. Collaborate with stakeholders to translate complex requirements into reliable...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$132K - $194K *

Unlock potential by leading the strategy and evolution of People technology and analytics. Drive data governance and insights to enhance decision-making and operational efficiency, while partnering wi...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$94K - $293K *

Transform enterprise data into actionable insights by architecting and managing AI-driven platforms. Lead data governance, integration, and quality assurance to ensure scalable, impactful solutions th...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$265K - $295K *

Shape community engagement strategies to foster trust and collaboration with local stakeholders, ensuring Anthropic's infrastructure projects benefit the communities we serve while navigating complex...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $220K *

Join a dynamic team as you drive customer success and retention for utility clients. Leverage your expertise to build strong relationships, execute strategic account plans, and elevate our mission in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$265K - $295K *

Drive community engagement and build trusted relationships with local stakeholders to ensure Anthropic's infrastructure projects are positively received and beneficial to the communities in Louisiana...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $170K *

Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $170K *

Champion the growth of Audit Manager by driving sales in the healthcare sector. Leverage your expertise in medical billing and coding to engage revenue cycle leaders, manage the sales pipeline, and de...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$121K - $182K *

Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $137K *

Lead the charge in cloud migration by managing infrastructure engineering tasks, executing migrations to Azure and AWS, and ensuring operational readiness for applications and services in a dynamic, r...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $145K *

Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in designing and implementing enterprise-grade data archival solutions. Oversee end-to-end delivery, ensuring compliance with security standards while collaborating across teams to opt...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$225K - $265K *

Shape the future of secure administration by leading a dynamic engineering team focused on backend services, user access, and account management. Drive innovation while ensuring operational excellence...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $171K *

Accelerate sales growth by managing and qualifying strategic Enterprise Intelligence opportunities. Collaborate with cross-functional teams, ensuring comprehensive engagement and communication to opti...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$141K - $196K *

Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Join a dynamic team to enhance financial management practices and support critical operations. Collaborate across levels to drive process improvements and deliver impactful financial insights in a fas...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $207K *

Drive impactful analytics in Medical Affairs by developing KPIs, analyzing data trends, and collaborating with cross-functional teams to enhance decision-making and resource allocation for optimal bus...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower clients by managing energy procurement operations, leading RFP processes, and delivering market insights. Collaborate with suppliers and customers to optimize strategies in deregulated electri...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Champion AI deployment by designing and implementing innovative solutions across multiple platforms. Collaborate with teams to enhance customer experiences while ensuring data governance and security...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $155K *

Drive data science initiatives to transform clinical and real-world data into actionable insights, supporting cross-functional teams in medical device research and development. Collaborate effectively...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Accelerate your career by managing full-cycle recruiting for engineering roles. Collaborate with hiring managers to build a strong talent pipeline and enhance candidate experience while supporting inn...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$218K - $256K *

Shape the future of customer engagement by leading the design and delivery of innovative ML systems. Collaborate with cross-functional teams to enhance automation, safety, and customer experience thro...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.