Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$130K - $155K *

Transform data into actionable insights by leading research initiatives, collaborating with business leaders, and developing predictive models to drive strategic decisions and enhance product offering...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$101K - $113K *

Advance your career by transforming complex data into actionable insights that drive financial and operational success. Collaborate with executives to solve high-impact data challenges and develop sca...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$223K - $317K *

Drive the evolution of a robust Fulfillment platform, shaping architecture and strategy while mentoring teams. Lead modernization efforts to enhance scalability, reliability, and performance, ensuring...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$92K - $126K *

Drive innovative solutions by blending product analytics and low-code development, collaborating cross-functionally to enhance AI Agent capabilities and optimize Revenue Cycle operations within the he...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$103K - $121K *

Champion project success by building pacing trackers and forecasting models, collaborating with Finance to enhance capacity planning and resource allocation, while providing leadership with real-time...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of digital transformation by leading a dynamic team to deliver innovative solutions that enhance business efficiency and customer experience across multi-functional AWS programs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Unlock your potential as a Senior Applied AI Engineer, leading teams to design and deliver impactful AI solutions. Drive technical excellence and mentor engineers while shaping the future of AI system...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$83K - $133K *

Lead customer engagement and technical design for critical power projects, ensuring quality and compliance. Collaborate across teams to resolve issues and manage multiple projects, driving successful...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$177K - $212K *

Develop and deploy advanced ML models for multi-object tracking, ensuring robust performance in autonomous vehicles. Collaborate with cross-functional teams to enhance tracking algorithms and improve...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$225K - $265K *

Lead and mentor a diverse team of backend engineers in EDR remediation, transforming insights into actionable product capabilities while managing scope and fostering collaboration across engineering t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Partner with us to lead a dynamic model audit team, enhancing financial modelling processes while driving strategic growth and innovation across projects, all while fostering a collaborative and high...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $155K *

Join a team that's redefining energy solutions by designing innovative fluid and power systems. As a Process Engineer, you'll drive the development and optimization of cutting-edge technologies in a f...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $145K *

Lead the charge in architecting and automating secure CI/CD pipelines and cloud infrastructure, ensuring compliance and resilience while delivering high-quality software through expert DevSecOps pract...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $185K *

Elevate your career by managing a dynamic data engineering team, shaping scalable data pipelines, and driving innovative data solutions to enhance enterprise data strategies and execution efficiency a...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$141K - $205K *

Unlock potential by serving as a strategic HR advisor, delivering impactful consultations and solutions across various HR topics to optimize workforce performance and support business growth in a dyna...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$68K - $143K *

Support audit and compliance efforts for DoD financial systems, ensuring adherence to GAGAS and federal standards. Collaborate with stakeholders to enhance internal controls and audit readiness, drivi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $143K *

Unlock insights as a Marketing Analytics Manager, driving data analysis across channels. Collaborate with teams to enhance reporting, measurement, and performance evaluation, while mentoring analysts...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$156K - $166K *

Champion laboratory data strategy and architecture for a transformative pharmaceutical initiative. Lead data governance, mapping, and migration planning while collaborating with cross-functional teams...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Drive AI transformation by leading client engagements, shaping strategies, and ensuring successful delivery. Build trusted relationships with stakeholders, oversee project execution, and mentor teams...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$63K - $177K *

Deliver intuitive, user-centered experiences for advanced AI products. Collaborate with cross-functional teams to design and develop engaging interfaces, dashboards, and applications that empower user...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Join a team that's redefining AI governance by developing frameworks and strategies that address enterprise needs while balancing risk and value for optimal outcomes...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$182K - $252K *

Champion data-driven decision-making by leveraging deep analytics expertise to guide product, marketing, and finance leaders. Drive strategic insights and build innovative tools that enhance business...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $202K *

Engineer robust data platforms by designing scalable pipelines and APIs that support AI-driven healthcare applications, ensuring high performance, security, and operational excellence in a collaborati...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $185K *

Lead the development of innovative AI products that empower job seekers with evidence-based coaching and actionable insights, while collaborating closely with cross-functional teams to shape impactful...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.