Zone Director, East

Mirum Pharmaceuticals

$130K — $180K *
US-AnywhereRemote in United States
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree required; advanced degree preferred (MBA, etc.)
  • 7+ years in pharmaceutical/biotech with 5+ years in leadership
  • Experience leading leaders (second-line leadership)
  • Significant expertise in rare disease, especially liver disease
  • Proven success in product launches, particularly first-in-class therapies
  • Strong understanding of market access and patient journeys
  • High ethical standards and commitment to compliance

Responsibilities

  • Drive Zone business performance with a strategic mindset
  • Execute and innovate zone-specific business plans
  • Analyze market trends to inform actions
  • Lead and develop first-line leaders for team effectiveness
  • Foster a culture of accountability and improvement
  • Ensure high-quality execution of brand strategy
  • Build strategic relationships with KOLs and top accounts

Benefits

  • Flexible work environment (remote options)
  • Opportunities for professional development
  • Competitive healthcare and wellness benefits
  • Travel opportunities for field engagements
  • Employee engagement initiatives and programs
Full Job Description
POSITION SUMMARY

The Zone Director is a second-line field leader responsible for driving commercial performance, building 4 high-performing Region Business Director (RBD) teams, and ensuring execution excellence across the liver portfolio. This role translates national strategy into regional impact, with a strong emphasis on rare disease expertise, patient-centricity, and cross-functional leadership.

Assigned Area: ME, NH, VT, NY, RI, MA, CT, NJ, PA, DE, MD, D.C., VA, OH, MI, IN, TN, NC, SC, GA, FL

JOB FUNCTIONS/RESPONSIBILITIES

Enterprise Leadership
  • Own and deliver Zone business performance across the liver portfolio with a strategic, big-picture mindset
  • Drive change and innovation
  • Develop and execute zone-specific business plans aligned to national strategy
  • Analyze market trends, competitive dynamics, and performance data to inform actions

Team Leadership & Development
  • Lead, coach, and develop first-line leaders to maximize team effectiveness
  • Build a strong leadership pipeline and succession plans
  • Foster a culture of accountability, engagement, and continuous improvement

Execution Excellence
  • Ensure consistent and high-quality execution of brand strategy in the field
  • Monitor KPIs and drive disciplined performance management
  • Identify and scale best practices across regions

Cross-Functional Collaboration
  • Partner with Marketing, Market Access, Medical Affairs, Patient Services and Operations
  • Ensure alignment on strategy and coordinated execution
  • Provide field insights to inform brand planning and lifecycle strategy

Market & Customer Engagement
  • Maintain strategic relationships with key opinion leaders (KOLs) and top accounts
  • Understand regional nuances in referral patterns and treatment pathways
  • Support teams in navigating complex access and reimbursement environments

Compliance & Ethical Leadership
  • Ensure all activities comply with regulatory, legal, and company policies
  • Model integrity and patient-first decision making
  • Reinforce a culture of compliance across the organization

QUALIFICATIONS

Education/Experience:
  • Bachelor's degree required; advanced degree preferred (MBA, etc.)
  • 7+ years pharmaceutical/biotech experience, plus minimum of 5 years of leadership experience
  • Successful experience leading leaders (second-line leadership) highly desired
    • Significant rare disease and/or specialty experience
    • Experience in rare liver disease a plus
    • Proven success in product launches, ideally with first-in-class therapies and in competitive markets
    • Demonstrated ability to build, lead, train and develop high-performing teams
    • Proven success in sales leadership roles with the ability to inspire, influence and align teams
  • Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and difficult access to therapies
  • Strong leadership presence with the ability to inspire, influence, and align teams
  • Strong understanding of market access, payer dynamics, and patient services
  • Demonstrated ability to lead in a matrixed organization
  • High integrity, ethical standards, and commitment to compliance
  • Thrives in a fast-paced, dynamic, and collaborative environment
  • Able to travel frequently, up to 70% overnight travel and has a valid drivers' license

#LI-REMOTE

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