Roche

US Medical, Business Strategy & Operations - Sr. Manager, Medical Operations

Roche$136K — $252K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree in a scientific, business, or analytical field.
  • 6+ years of relevant experience in the pharmaceutical or biotechnology industry.
  • Expertise in drug development lifecycles and Medical Affairs operations.
  • Proven ability to influence senior stakeholders and mobilize multidisciplinary teams without formal authority.
  • Strong problem-solving skills in ambiguous situations.

Responsibilities

  • Lead the operationalization of Strategic Medical Planning into execution roadmaps.
  • Manage end-to-end project management for complex initiatives, overseeing schedules and resources.
  • Facilitate high-impact meetings to drive alignment and prioritize actions.
  • Coach teams in agile methodologies to enhance decision-making and clarity.
  • Manage governance and coordinate with external partners on deliverables.
  • Identify process gaps and collaborate on scalable operational solutions.
  • Develop change management and communication plans to foster collaboration across teams.

Benefits

  • Hybrid work schedule with 3 days on campus per week.
  • Discretionary annual bonus opportunities based on performance.
  • Healthcare and wellness benefits, including options for physical and mental well-being.
  • Professional development support for continued learning and growth.
Full Job Description

The Opportunity

As the US Medical (USM) Business Strategy and Operations (BSO) Senior Manager, you will serve as an indispensable strategic thought partner and operational engine to US Medical leaders and cross-functional teams. Operating in an impactful individual contributor capacity, you will bridge medical strategy with world-class execution—ensuring our networks deliver on critical priorities that bring clinical evidence to healthcare stakeholders and patients. You will champion agile ways of working, facilitate high-stakes cross-functional initiatives, and streamline business processes across our dynamic healthcare landscape.

Key Responsibilities:

  • Lead the operationalization of Strategic Medical Planning, translating high-level medical strategies into structured, milestone-driven execution roadmaps.

  • Drive end-to-end project management across complex initiatives, establishing schedules, managing budgets and resources, mitigating delivery risks, and tracking tangible medical impact.

  • Facilitate high-impact network and functional meetings, driving alignment, active team inclusion, ruthless tactical prioritization, and decisive action tracking.

  • Foster an agile team environment by coaching cross-functional partners in lean and agile ways of working (Kanban, Scrum, Miro, Smartsheet) to accelerate decision-making and cross-organizational clarity.

  • Manage cross-functional governance and partner interfaces, including potential alliance management accountabilities to coordinate goals and deliverables with external collaborators.

  • Proactively identify business process gaps, partnering with Compliance and Operations SMEs to simplify workflows and design scalable, compliant operational solutions.

  • Spearhead change management and strategic communication plans that reinforce Genentech’s Operating Principles and break down organizational silos across USMA and Global networks.

Who you are

  • You hold a Bachelor’s degree in a scientific, business, or related analytical field.

  • You bring 6 or more years of relevant professional experience within the pharmaceutical or biotechnology industry, with focused experience in Medical Affairs, strategic operations, or complex project management.

  • You possess demonstrated expertise in drug development lifecycles, commercialization pathways, and the operational cadence of Medical Affairs organizations.

  • You have a proven track record of influencing senior stakeholders and mobilizing matrixed, multidisciplinary teams without formal authority.

  • You are comfortable navigating ambiguity, utilizing sound judgment to prioritize ruthlessly, and solving multifaceted process challenges through collaborative problem-solving.

Preferred

  • Advanced degree (PharmD, PhD, MS, or MBA).

  • Project Management Professional (PMP) certification, Agile/Scrum Master certification, or equivalent credentials.

  • Hands-on experience implementing enterprise collaboration platforms and agile work tracking tools (e.g., Smartsheet, Miro, Trello, Jira).

  • Proven experience managing external vendor partnerships or alliance management frameworks.

Location

  • This role is based in South San Francisco and offers a hybrid schedule working 3 day per week on campus

  • No relocation benefits are available for this posting

The expected salary range for this position based on the primary location of CA is $136,100 -$252,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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