Tempus

Staff/Senior Machine Learning Engineer, Clinical AI

Tempus$170K — $230K *
Healthcare
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Strong command of Python in production environments
  • Experience designing, building, and integrating with microservices
  • Deployed data orchestration workflows in production using Airflow or equivalent
  • Worked on cloud-native services, preferably GCP
  • Built monitoring, observability, and alerting for production systems
  • Hands-on experience with major ML frameworks like LangGraph, PyTorch, or equivalents
  • Excellent written and verbal communication, with experience authoring and reviewing design docs

Responsibilities

  • Build and operate production AI pipelines with focus on reliability, cost, and latency
  • Design and maintain Airflow-based orchestration for clinical workflows
  • Establish observability metrics and alerting to catch regressions early
  • Develop eval infrastructure to continuously measure model output quality
  • Ship platform tooling and SDKs to support Machine Learning Scientists
  • Collaborate with ML Scientists to debug model outputs
  • Participate in on-call rotation and incident management
  • Partner with infrastructure teams to optimize cloud services
  • Author and review cross-pod design documentation
  • Enhance engineering standards through code and design reviews

Benefits

  • Full range of benefits including incentive compensation and restricted stock units
  • Comprehensive medical and other healthcare benefits
  • Flexible work arrangements, including remote options
  • Opportunities for professional growth and development
  • Collaborative work environment with innovative projects
Full Job Description

What You Will Do:

  • Build and operate production AI pipelines: LLM-powered extraction, batch orchestration, and inference, with a focus on reliability, cost, and latency

  • Design and maintain Airflow-based orchestration for batch clinical workflows

  • Build the observability (metrics, logging, alerting) that catches regressions before they reach downstream consumers

  • Build and maintain eval infrastructure that measures clinical model output quality continuously: regression detection, drift, gold-set management, dashboards

  • Ship platform tooling and SDKs that accelerate Machine Learning Scientists and downstream consumers

  • Partner with Machine Learning Scientists to debug bad model outputs to root cause (data, prompt, or pipeline)

  • Participate in the pod's on-call rotation

  • Collaborate with platform / infrastructure teams to leverage GCP services for performance, security, and cost-efficiency

  • Author and review design docs for cross-pod work

  • Raise the engineering bar through code review and design review

Required Qualifications:

  • Strong command of Python in production environments

  • Experience designing, building, and integrating with microservices in production

  • Deployed data orchestration workflows in production (Airflow or equivalent)

  • Worked on cloud-native services (GCP preferred but not required)

  • Built monitoring, observability, and alerting for production systems

  • Hands-on experience with at least one major ML framework 6 we primarily use LangGraph; PyTorch, spaCy, or equivalents are equally welcome

  • Strong written and verbal communication, including experience authoring and reviewing design docs (RFCs, PRDs, or equivalent); partners well with research scientists, PMs, and clinicians

Preferred Qualifications:

  • Operated production systems hands-on 6 on-call rotations, incident response, postmortems

  • Experience building eval / quality measurement systems for ML or LLM outputs

  • Hands-on production LLM application experience (prompts, agents, RAG, LLM evals, extraction pipelines)

  • Built internal platforms or SDKs that other engineers / scientists depended on

  • Experience working with clinical or biomedical data (EHR, genomics, pathology, clinical notes)

  • Contributions to relevant open-source projects

#LI-BL1

New York Pay Range - $170,000-a0$230,000a0USD

California Pay Range - $170,000-a0$230,000a0USD

Illinois Pay Range - $150,000-a0$210,000a0USD

Remote - USA Range - $150,000-a0$210,000a0USD

The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

About Tempus

Tempus is a technology company that has built an operating system to battle cancer. The company enables physicians to deliver personalized cancer care for patients through its interactive analytical and machine learning platform. Tempus provides genomic sequencing services and analyzes molecular and therapeutic data to empower physicians to make real-time, data-driven decisions. The company also offers research services to enable discovery of new therapeutic targets and clinical services that support clinical trial design and monitoring. Tempus was founded in 2015 by Eric Lefkofsky and has raised over $8 billion in funding to date.
Learn more about Tempus
Size
1,001 employees
Industry
Founded
2015

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