HeartFlow

Staff/Senior Agentic AI Engineers (Multiple roles)

HeartFlow$180K — $250K *
Healthcare
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 5+ years (Senior) or 8+ years (Staff) of software engineering experience in production environments.
  • Hands-on experience with Large Language Models and agentic architectures.
  • Familiarity with orchestration frameworks and vector databases.
  • Advanced proficiency in Python or Go, with knowledge of microservices and API design.
  • Passion for greenfield projects, thriving in ambiguity and complexity.

Responsibilities

  • Design and implement a secure, scalable Agentic AI platform for multi-agent orchestration.
  • Drive technical execution from ideation to production for agent-driven features.
  • Implement safety guardrails and evaluation frameworks for medical contexts.
  • Enable agents to interact with complex medical data and internal APIs.
  • Collaborate with product managers and clinical experts to develop AI architectures.
  • Mentor junior engineers and promote software engineering best practices.

Benefits

  • Hybrid work environment promoting flexibility.
  • Opportunity to work on groundbreaking AI initiatives in healthcare.
  • A clear path for mentorship and professional growth within the team.
  • Participation in shaping the technical strategy and architecture for novel AI products.
  • Engagement with a diverse team of product managers, clinicians, and data scientists.
Full Job Description
About the role(s)

To accelerate this mission, we are hiring for multiple roles across both the Senior and Staff levels.

As a founding member of our new Agentic AI initiatives team, you will step into a role that is a unique hybrid of platform architecture and greenfield product engineering. You won't just be consuming AI models; you will be responsible for setting up the core ecosystem that allows autonomous, intelligent agents to execute multi-step medical reasoning and data workflows securely and at scale.

Whether you join us at the Senior level to drive execution or at the Staff level to help shape technical strategy and architecture, you will have a true blank-canvas opportunity to design production-grade agentic systems from scratch, directly translating our decade-plus of clinical AI success into the next generation of autonomous medical technology.
Job Responsibilities
  • Design and implement a robust, secure, and scalable Agentic AI platform, establishing standard patterns for multi-agent orchestration, state management, tool usage, and memory.
  • Drive the technical execution of brand-new, agent-driven product features from initial ideation to production deployment. You will build systems to parse requirements, map software modules, and auto-generate test cases - boosting engineering velocity without sacrificing the compliance rigor required for FDA-cleared software.
  • Implement advanced guardrails, evaluation frameworks, and reasoning validation loops to ensure agent behaviors are safe, deterministic, and highly accurate within a medical context.
  • Enable agents to interact dynamically with complex medical data structures, Electronic Health Records (EHRs), imaging pipelines, and internal APIs.
  • Work closely with product managers, clinical experts, and data scientists to translate clinical needs into technical AI agent architectures.
  • Mentor junior/mid-level engineers, champion software engineering best practices (CI/CD, comprehensive testing, logging for non-deterministic systems), and stay ahead of the rapidly evolving AI landscape.
Required Qualifications
  • 5+ years (Senior) or 8+ years (Staff) of professional software engineering experience, with a proven track record of shipping production-grade software.
  • Deep, hands-on experience building applications with Large Language Models (LLMs) and a strong understanding of agentic architectures.
  • Experience with orchestration frameworks and vector databases.
  • Advanced proficiency in Python or Go, alongside a solid grasp of microservices, API design, and cloud infrastructure (AWS or GCP).
  • A passion for greenfield projects - you thrive in ambiguity, enjoy designing systems from scratch, and love solving complex, open-ended problems.
Nice-to-Have
  • Experience deploying AI applications in regulated industries (Healthcare, Finance, etc.) or navigating HIPAA/GDPR compliance.
  • Active contributions to open-source LLM or Agentic AI frameworks.
  • Experience with advanced prompt engineering, fine-tuning, or RAG optimization.

A reasonable estimate of the base salary compensation range is $180,000 to $215,000 (for Senior level), $200,750 to $250,922 (for Staff level), cash bonus, and equity. #LI-IB1 #LI-Hybrid

About HeartFlow

HeartFlow is a medical technology company that specializes in non-invasive, personalized cardiovascular disease diagnosis and treatment planning. The company's technology uses artificial intelligence and deep learning algorithms to create 3D models of patients' hearts and simulate blood flow. HeartFlow's technology has been used in over 30,000 patients worldwide and has been shown to improve patient outcomes and reduce healthcare costs. The company was founded in 2007 and is headquartered in Redwood City, California.
Learn more about HeartFlow
Size
500 employees
Industry
Founded
2009

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