AstraZeneca

Sr. Scientist, Translational Proteomics, Biomarker Science and Technologies

AstraZeneca$116K — $174K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a scientific discipline.
  • Experience in the pharmaceutical industry, specifically in early drug development.
  • Strong understanding of proteomics and biomarker research.
  • Knowledge of regulatory compliance in scientific research.
  • Ability to work both independently and as part of a team; strong communication skills.

Responsibilities

  • Develop MS-based proteomics technologies for clinical studies.
  • Validate protocols for clinical sample processing according to SOPs.
  • Produce and maintain PRM and DIA data in collaboration with bioinformatics teams.
  • Operate and maintain LC-MS instruments while implementing quality control measures.
  • Analyze and summarize data, presenting findings to support decision-making.

Benefits

  • Eligible for various short-term incentive bonuses.
  • Equity-based awards for salaried roles and commissions for sales roles.
  • Qualified retirement programs.
  • Paid time off including vacation and holidays.
  • Health, dental, and vision coverage as per applicable plans.
Full Job Description
The Sr. Scientist Translational Proteomics develops proteomics technologies, validates protocols, and analyzes data for biomarker research. The role operates LC-MS instruments, collaborates across teams, and ensures compliance with scientific regulations.

Typical Accountabilities
  • Develop MS-based proteomics technologies for clinical biomarker studies to ensure robust translational research.
  • Validate and implement protocols for processing clinical samples, including tissue and plasma, following SOPs.
  • Generate and maintain PRM and DIA data to support clinical studies and collaborate with bioinformatics teams to confirm biomarker clinical utilities.
  • Operate LC-MS instruments, apply strict QC measures, conduct routine maintenance, and adopt new technologies to enhance protocols.
  • Analyze data, summarize outcomes, and present findings at functional and project reviews to streamline decision-making processes.


Education, Qualifications, Skills & Experience

Essential
  • Bachelor's degree in a scientific discipline
  • Relevant experience in the pharmaceutical industry and early drug development phases of the drug development process
  • Comprehensive understanding of current principles and concepts within the role-specific field
  • Familiarity with regulations and compliance systems related to scientific work; Broad understanding of R&D disciplines; Awareness of patent and intellectual property issues
  • Ability to work independently and collaboratively; Excellent communication skills.


Desirable
  • Master's degree in a related field
  • Advanced knowledge in the subject area
  • Advanced degree within the field and/or professional certification
  • Well-developed understanding of drug metabolism processes and pharmacokinetics
  • Well-developed understanding of the creation of biosignatures and biomarker analysis.


The annual base pay for this position ranges from $116,284.00 - $174,426.00. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted
19-Aug-2026

Closing Date
04-Sep-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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