McKesson

Sr. Director, Infrastructure Automation & Compliance

McKesson$151K — $201K *
Enterprise Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • 13+ years of professional experience in audit, compliance, risk management, or infrastructure governance.
  • 6+ years of leadership experience in managing enterprise-level teams.
  • Proven success in leading large-scale audit programs, particularly SOX and ITGC compliance audits.
  • Experience in driving automation within compliance and operational processes.
  • Preferred background in enterprise infrastructure, cloud, or data center environments.

Responsibilities

  • Lead enterprise-wide audit readiness strategy for data center and infrastructure environments.
  • Engage with internal and external auditors, as well as regulatory bodies, to strengthen compliance relationships.
  • Oversee the entire audit lifecycle from planning to remediation tracking.
  • Ensure consistent implementation of control frameworks such as SOX ITGC and operational controls.
  • Implement strategies to automate the audit evidence collection and control monitoring processes.
  • Design and establish standardized governance and risk control frameworks for infrastructure initiatives.
  • Serve as an advisor to senior leadership on compliance risks and audit strategies.

Benefits

  • Competitive compensation package including performance-based incentives.
  • Opportunities for professional development and career growth.
  • Access to a comprehensive health and wellness program.
  • Flexible work arrangements and paid time off options.
Full Job Description
Position Summary

The Senior Director of Audit, Compliance & Automation (M5) is a senior enterprise leader responsible for driving end-to-end audit readiness, compliance execution, and large-scale automation of control processes across infrastructure platforms and services.

This role provides strategic direction, governance, and operational leadership to ensure regulatory adherence, audit excellence, and continuous control optimization. It integrates audit, GRC frameworks, and automation engineering to transform compliance from a reactive process into a proactive, scalable, and technology-enabled capability.

Operating at the intersection of compliance, infrastructure operations, and automation, the role partners with executive leadership, audit committees, and platform teams to ensure enterprise-wide control effectiveness, risk transparency, and measurable improvements in audit outcomes.

Key Responsibilities

1. Enterprise Audit & Compliance Leadership

  • Lead enterprise-wide audit readiness strategy across data center, infrastructure, and platform environments.


  • Own relationship with internal audit, external auditors, and regulatory bodies.


  • Oversee audit lifecycle (planning, walkthroughs, evidence collection, remediation tracking).


  • Ensure consistent execution of control frameworks (e.g., SOX ITGC, security, operational controls).


  • Drive closure of audit findings, ensuring sustainable remediation and root-cause elimination.


2. Automation of Controls & Audit Processes

  • Define and execute a strategy to automate audit evidence collection, control monitoring, and certification workflows.


  • Partner with engineering and platform teams to embed automated controls into infrastructure systems.


  • Lead adoption of tools (e.g., ServiceNow GRC, workflow platforms) to digitize compliance processes.


  • Drive continuous control monitoring (CCM) and real-time risk visibility.


  • Eliminate manual audit processes through intelligent automation and integration.


3. Governance, Risk & Controls Strategy

  • Design and implement enterprise GRC frameworks integrated with infrastructure transformation initiatives (DDC exit, cloud migration, colo consolidation).


  • Establish standardized control libraries, policies, and governance models across platforms.


  • Lead risk identification, assessment, and mitigation strategies for infrastructure services.


  • Provide executive dashboards and reporting on compliance posture, risk exposure, and audit health.


4. Operational Integration with Infrastructure Teams

  • Embed compliance and audit requirements into run and build operating models.


  • Ensure controls are integrated into day-2 operations, provisioning workflows, and platform engineering standards.


  • Partner with infrastructure leaders to align audit compliance with transformation initiatives (cloud, EUC, data center exits).


  • Drive accountability for control ownership across engineering and operations teams.


5. Executive Advisory & Stakeholder Engagement

  • Serve as a trusted advisor to EITP Infrastructure VP and senior leadership on audit risk, compliance posture, and regulatory exposure.


  • Prepare executive briefings for audit committees and SteerCos.


  • Represent Infrastructure in enterprise compliance and audit forums.


  • Translate audit and control requirements into business-aligned strategies.


6. Organizational Leadership & Talent Development :

  • Build a high-performing organization blending audit expertise, compliance professionals, and automation engineers.


  • Develop talent pipelines and succession plans for critical governance and automation roles.


  • Foster a culture of accountability, transparency, and continuous improvement.


Minimum Requirements:
  • Degree or equivalent experience. Typically requires 13+ years of professional experience and 6+ years of diversified leadership, planning, communication, organization, and people motivation skills (or equivalent experience).


Critical Skills:

  • 8+ years of experience in audit, compliance, risk management, or infrastructure governance.


  • 8+ years of leadership experience managing enterprise-scale teams and programs.


  • Proven experience leading large-scale audit programs (SOX, ITGC, regulatory audits).


  • Experience driving automation in compliance or operational processes.


  • Background in enterprise infrastructure, cloud, or data center environments strongly preferred.


Technical & Functional Expertise:

  • IT General Controls (ITGC) / SOX compliance


  • Audit lifecycle, walkthroughs, evidence management


  • Risk management frameworks and control design


  • ServiceNow GRC or similar platforms


  • Workflow automation and reporting tools


  • Infrastructure environments (compute, network, storage, DC operations)


  • Strong understanding of integrating compliance into engineering and operational processes


Leadership Competencies:

  • Strategic thinking and enterprise influence


  • Executive communication and stakeholder management


  • Ability to drive transformation across siloed teams


  • Strong governance and decision-making discipline


  • Data-driven mindset with focus on measurable outcomes


We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$151,200 - $201,600

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

About McKesson

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry. The Company operates in two segments. The McKesson Distribution Solutions segment delivers ethical drugs, medical-surgical supplies and equipment and health and beauty care products throughout North America. This segment also provides specialty pharmaceutical solutions for biotech and pharmaceutical manufacturers, sells financial, operational and clinical solutions for pharmacies (retail, hospital, long-term care) and provides consulting, outsourcing and other services. The McKesson Technology Solutions segment delivers enterprise-wide clinical, patient care, financial, supply chain, strategic management and software solutions. In July 2011, the Company acquired Portico Systems from Safeguard Scientifics, Inc. On March 25, 2012, it acquired the independent banner and franchise businesses of Katz Group Canada Inc. McKesson Distribution Solutions delivers pharmaceuticals to retail pharmacies and institutional providers like hospitals and health systems. They operate pharmaceutical distribution centers across the country, serving customers in all 50 states. They also deliver a comprehensive offering of health care products, technology, equipment and related services to the alternate site market, including physician offices, surgery centers, long-term care facilities and home care businesses across the country. McKesson is currently the largest pharmaceutical distributor in North America. McKesson also operates McKesson Canada and has an equity holding in Nadro, a leading distributor in Mexico.

McKesson Careers

Join McKesson, a leading global healthcare company, and be part of a team that is redefining the future of healthcare. With a variety of job opportunities available, McKesson is the perfect place to advance your career, whether you're a seasoned professional or just starting out. Work You’ll Do At McKesson, we are committed to improving care in every setting—one product, one partner, one patient at a time. We’re seeking talented professionals to join our team and contribute to a culture of innovation, diversity, and leadership. Our employees are driven by a deep sense of purpose and a desire for continuous growth and improvement. Empower Your Future in Healthcare With positions ranging from internships to leadership roles, McKesson offers unparalleled employment opportunities to develop your skills and advance your career. Our commitment to diversity training ensures that all team members have the opportunity to thrive. Join a team where your skills will be honed, your professional growth will be supported, and where you can genuinely see the difference you make in the lives of patients around the world. Innovative Work Environment McKesson is at the forefront of healthcare innovation. Our team is constantly exploring new ways to improve patient outcomes and streamline care processes. This commitment to innovation is what sets us apart and what makes McKesson an exciting place to work. Career Development and Benefits McKesson believes in nurturing the potential of its employees through robust career development programs and comprehensive benefits designed to support your life and well-being. From leadership training to health and wellness benefits, we ensure our team members are equipped to meet their professional and personal goals. Explore Job Opportunities Whether you’re looking for an internship to kickstart your career, or a senior position to utilize your extensive experience, McKesson offers a range of opportunities. Explore our open positions and find where you can make a difference at McKesson. Stay Connected Join Our Team Search for open positions that match your skills and interests. We are looking for passionate, curious, and solution-driven team players who are ready to take the next step in their careers. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Networking and Professional Growth At McKesson, networking and professional growth are part of our everyday environment. We encourage our employees to connect, share, and learn from each other to foster personal and professional development. Job Alert Emails Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await you at McKesson. Join McKesson today and be part of a team that is dedicated to shaping the future of healthcare.
Learn more about McKesson
Size
58,000 employees
Market Cap
$53.7 billion
Industry
Net Income
-$4.1 billion
Founded
1833
5 Year Trend
+5.9%
Revenue
$237.6 billion
NASDAQ

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