Job Description

Role Overview

The Quantitative Pharmacology and Pharmacometrics – Immune/Oncology (QP2-IO) Department of our Company's Research Laboratories is seeking a curious and collaborative Senior Scientist to support our rapidly expanding oncology pipelines.

As a senior specialist you will be part of a cross-functional teams of experienced scientists to discover and develop novel therapeutic agents in oncology. The senior specialist is a skilled quantitative scientist, with a good understanding of the strategic elements of drug discovery and development. The senior specialist should demonstrate collaborative work spirit and excellent communication skills.

Within QP2-IO, you have a unique opportunity to accelerate your professional career as a quantitative drug developer taking advantage of our end-to-end pipeline support in one of the world’s most research-intensive biopharmaceutical companies.

Primary Responsibilities:

Contribute to the development of model-based strategies (translational PK/PD strategies, mechanistic model, POPPK/PD, clinical trial simulations,etc) for quantitative analyses, within and across development programs and/or departments, to inform and optimize drug discovery and all phases of drug development including, but not limited to dose selection, clinical trial design, and go/no-go decisions.

Represent QP2-IO on oncology discovery, early clinical development and late clinical development teams, leveraging quantitative approaches to drive streamlined development of programs within our growing portfolio.

Collaborate with other functional areas, as well as with external vendors and partners, on activities related to study design, protocol development, study execution, reporting and interpretation of data.

• A Ph.D. with 0-2 years experience

OR

• PharmD or MS or equivalent degree with preferably 2-4 years of relevant experience, where “experience” means having a record of increasing responsibility and independence in a similar role in pharmaceutical drug development, regulatory agency, or academia.

• Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical/biomedical engineering, or a related field.

• Experience in performing population PK, PK/PD analyses using standard pharmacometrics software (e.g. NONMEM, Monolix, Phoenix, etc.).

• Good written and verbal communication, interdisciplinary collaboration, and problem scoping and planning.

• Knowledge in oncology clinical drug development programs.

• Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.

• Scientific understanding of biopharmaceutical and ADME properties of small molecules and/or biologics.

his opportunity will be hybrid or remote, but the remote position is only applicable for those that are not within commutable distance to primary sites noted in posting.  If commutable, the position will be hybrid. Please note that standard commute is (less than) <50 miles."

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Required Skills:

Preferred Skills:

Current Employees apply

Current Contingent Workers apply

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please if you need an accommodation during the application or hiring process.

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

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