Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)

Syneos Health Careers$79K — $139K *
US-Anywhere
+ 51 other locationsRemote
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 4+ years of experience in a high-volume work environment
  • Experience negotiating with large academic institutions
  • Strong project management skills with the ability to lead cross-functional teams
  • Comprehensive understanding of clinical study protocols and timelines
  • Bachelor's degree required
  • Oncology therapeutic area experience preferred
  • Experience in pharma, CRO, or investigative sites beneficial

Responsibilities

  • Negotiate site budgets and clinical trial agreements from start to finish
  • Understand budgeting and contract language for Pharma & Vaccine trials
  • Develop templates to ensure compliance and strategic focus
  • Lead negotiations with major academic institutions
  • Draft and finalize clinical trial agreements balancing objectives and protections
  • Conduct due diligence and assessments on budget negotiations
  • Prioritize and manage multiple contracting projects effectively
  • Communicate updates and maintain departmental trackers

Benefits

  • Health benefits including medical, dental, and vision
  • Company car or car allowance offered
  • 401k with company match
  • Opportunity to participate in Employee Stock Purchase Plan
  • Eligibility for performance-based commissions or bonuses
  • Flexible paid time off (PTO) and sick leave
Full Job Description
Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)

Job Responsibilities

Senior Site Contracts Manager (Sponsor-Dedicated /Remote - US Based)

Are you a contracts expert who thrives on navigating complexity, building strong site partnerships, and driving timelines forward? Syneos Health is seeking a Senior Site Contracts Manager to support a sponsor-dedicated program focused on high-impact Pharma & Vaccine studies. If you're energized by problem-solving, negotiation, and leading projects across multiple therapeutic areas-especially oncology-we'd love to meet you.

About the Role:

As a Senior Site Contracts Manager, you'll serve as a strategic expert responsible for developing, negotiating, and managing US site budgets and clinical trial agreements. You'll collaborate closely with internal teams, external stakeholders, and major academic institutions to craft robust contracts that support operational excellence while minimizing risk.

This role is perfect for a communicator, leader, and negotiator who's ready to hit the ground running and make an immediate impact.

Key Responsibilities:

Budgeting & Template Development
  • Negotiate budgets from start to finish from a Sponsor perspective directly with clinical sites.
  • Fully understand budget and contract language for Pharma & Vaccine clinical trials.
  • Develop and refine templates to support consistency, compliance, and strategic study needs.


Contract Negotiation & Risk Management
  • Lead direct negotiations with large academic institutions and other critical stakeholders.
  • Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections.
  • Conduct due diligence checks-such as FMV assessments and site justification reviews-when initial offers are declined.
  • Determine when requests require budget or language escalation and secure appropriate approvals.


Project Leadership & Delivery
  • Prioritize and lead multiple contracting projects across several therapeutic areas (oncology experience strongly preferred).
  • Proactively escalate risks, timeline impacts, or delays that could affect CTA execution.


Tools, Systems & Communication
  • Demonstrate expert proficiency in Excel and clinical trial management systems.
  • Communicate effectively in both written and verbal formats, incorporating feedback seamlessly.
  • Maintain accurate and timely updates in departmental trackers and databases.


Compliance, Collaboration & Continuous Improvement
  • Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies.
  • Build strong working relationships with internal and external partners.
  • Support and train additional team members as needed.
  • Contribute to process improvement initiatives that simplify workflows and eliminate inefficiencies.
  • Take on ad-hoc tasks and diverse projects with a solutions-oriented mindset.


Preferred Qualifications:
  • Oncology therapeutic area experience
  • Prior experience with pharma, CRO, or investigative sites
  • Strong project management skills and comfort leading cross-functional efforts
  • Experience leveraging AI in the contracts and budgets space


What You Bring (Minimum qualifications):
  • 4+ years of experience working in a fast paced and volume driven work environment
  • Direct experience negotiating with large academic institutions
  • Ability to juggle priorities, lead projects, and deliver results under tight timelines
  • Strong understanding of clinical study protocols, timelines, and site-related milestones (e.g., SIV)
  • Bachelors degree


If you're ready to elevate your contracting career in a critical sponsor-dedicated role-and join a team driven by trust, transparency, and high performance-this is your opportunity!

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:
$79,800.00 - $139,600.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

About Syneos Health Careers

Syneos Health Careers

Joining Syneos Health presents an unparalleled opportunity to become part of a global team of professionals dedicated to biopharmaceutical solutions. At Syneos Health, job opportunities abound, offering a gateway to enhancing career paths in a company celebrated for its commitment to therapeutic and operational excellence.

Work That Matters

Syneos Health is at the forefront of healthcare innovation, collaborating on projects that integrate smart technology and human ingenuity to improve patient outcomes. This dynamic company is actively seeking professionals who are eager to drive progress in the biopharmaceutical field through diverse job opportunities ranging from scientific roles to operational positions.

Innovative Employment Opportunities

Syneos Health offers a variety of positions that cater to a range of skills and experiences, from entry-level to senior leadership roles. Employment at Syneos Health means contributing to a culture that values diversity and inclusion, ensuring every team member’s voice is heard and valued.

Internship Programs and Professional Growth

For those starting their career, Syneos Health provides robust internship programs designed to foster professional growth and build essential industry skills. Interns at Syneos Health gain hands-on experience, beneficial for future employment opportunities within the company or the broader healthcare industry.

Cultivating Leadership and Professional Development

Syneos Health is committed to the professional development of its employees, offering leadership training and career growth opportunities that encourage innovation and leadership skills. Employees are supported through comprehensive benefits, diversity training, and initiatives that promote personal and professional growth.

Join a Team of Experts

The team at Syneos Health is composed of industry-leading experts who bring a wealth of knowledge and experience to the company. Networking within Syneos Health’s global community allows for unparalleled professional development and insights into the latest industry trends.

Explore Career Opportunities

Syneos Health is hiring! Explore the numerous positions available that match a variety of skills and interests. The company looks for driven, curious, and innovative team players ready to make a significant impact in the healthcare industry.

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