AbbVie

Senior Scientist II, Technical Operations

AbbVie • $100K — $130K *
North Chicago, IL 60064In-Person
Pharmaceuticals & Biotech
8 - 10 years of experience
Today
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Job Overview by Ladders

Qualifications

  • BS, MS, or PhD in Chemical Engineering or Chemistry with relevant industry experience
  • 10+ years of experience for BS, 8+ for MS, 4+ for PhD
  • Familiarity with modeling and simulation tools like MATLAB, Python, or COMSOL
  • Experience in process development with knowledge of unit operations in small molecule synthesis
  • Demonstrated experience in scaling processes from lab to pilot plant

Responsibilities

  • Manage technical aspects and project schedules for processes in the API Pilot Plant
  • Collaborate with project teams to optimize scale-up processes and equipment
  • Provide technical oversight and troubleshooting during production in the pilot plant
  • Act as the primary liaison between various departments, ensuring smooth communication
  • Develop data-driven models to aid in the scale-up and tech transfer processes
  • Evaluate and implement new technologies to improve operational efficiency
  • Support PAT implementation, including data collection and equipment setup

Benefits

  • Paid time off including vacation, holidays, and sick leave
  • Medical, dental, and vision insurance
  • 401(k) plan eligibility
  • Participation in long-term incentive programs
Full Job Description
Job Description

The Process Engineering and API Clinical Supplies (PEACS) organization within AbbVie's Synthetic Molecule CMC (Chemistry, Manufacturing, and Control) Division in Development Sciences invents synthetic processes to prepare active pharmaceutical ingredients (APIs) to enable the development of AbbVie's pipeline and supply materials for clinical programs. AbbVie is seeking a highly motivated individual with a proven track record of accomplishment to join the API Pilot Plant Technical Operations (Tech Ops) group. This position will serve as a liaison between the synthetic molecule CMC scientific functions and the API Pilot Plant organization to ensure safe and robust scale up of API manufacturing processes. The successful candidate will assist in the optimization and scale-up of synthetic processes and facilitate the implementation of new technologies in the API Pilot Plant. The Scientist will also provide technical oversight during production campaigns and will support technical transfer to the ultimate commercial manufacturing site.

Responsibilities:
  • Technical and project management of processes entering the API Pilot Plant, including scheduling, equipment selection, materials tracking, authoring direction sets, obtaining safety analyses, and executing pre-runs.
  • Partner with API project teams to optimize processes for scale-up. Identify appropriate equipment, sizing, and configurations.
  • Technical oversight of processes running in the API Pilot Plant, and responsibility for process-troubleshooting in collaboration with the API project teams.
  • Serves as the primary point of contact between API Pilot Plant, API project teams, Quality Assurance, and Environmental Health and Safety.
  • Build data-driven and knowledge-driven models to facilitate successful scale-up and tech transfer.
  • Identify, evaluate, and implement new technologies for the pilot plant and/or identify opportunities to modify or leverage existing assets to enhance operational efficiency, which strategically align with the long-term goals of the API Pilot Plant. Examples include automation, flow chemistry, novel separations, Process Analytical Technology (PAT), feedback control, and drying technologies.
  • Support the implementation of PAT. Assist with equipment specification, setup, data collection, and analysis.
  • Support the introduction of new modalities into the plant.
  • Interface with API project teams to ensure that processes are safe, scalable, and operable.
  • Assist with technology transfer of late-stage processes to commercial sites, including process fit, identification of equipment needs, and facility modifications.
  • Responsible for review and documentation of data for cGMP execution of chemical processes. Authors campaign summary reports.
  • Exhibit a collaborative nature in identifying process challenges and communicate findings and recommendations effectively by multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, quality assurance specialists, and regulatory affairs specialists.
  • Author publications and present at scientific conferences.


Qualifications

Level and compensation will be commensurate with experience.
  • BS, MS, or PhD in Chemical Engineering or Chemistry with relevant industry experience:
  • 10+ years for BS
  • 8+ years for MS
  • 4+ years for PhD
  • Familiarity with modeling and simulation tools such as MATLAB, Python, C++, COMSOL, Scale-Up Suite, or M-Star.
  • Experience in process development and strong working knowledge of unit operations commonly used in small molecule synthesis (e.g., reactions, separations, distillation, crystallization, etc).
  • Demonstrated experience scaling chemical processes from the laboratory to the pilot plant.
  • Solid understanding of fundamental chemical scale-up and process safety principles.

Preferred
  • 3+ years of experience in pharmaceutical development and/or scaling processes from lab to the pilot scale.
  • Experience partnering with EHS for the scale-up of safe processes.
  • Advanced understanding of chemical processing engineering principles.

Key Leadership Competencies
  • Builds strong relationships with peers and cross functionally with partners to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  • Strong interpersonal and communication skills with demonstrated ability to work within a team environment.


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

Explore Job Opportunities

AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

Networking and Career Advancement

At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

Join Our Team

Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference.

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Explore AbbVie Jobs

Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Pharmaceuticals & Biotech
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ
ABBV
* Ladders Estimates

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