Job DescriptionAbbVie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines. Careers in AbbVie Biologics Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.
The biologics early analytical development group develops state-of-the-art analytical techniques for analysis of therapeutic proteins and other novel biologic molecules using separation science and other biophysical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.
The candidate will focus on development and implementation of analytical assays for the analysis of complex biologics including antibodies, antibody drug conjugates, and new modalities. The candidate will use and develop a variety of analytical techniques including chromatography, electrophoresis, spectroscopy, and automated methods. The successful candidate will contribute to the development and testing of complex and automated assays and will contribute to the continuous improvement and innovation within the group.
Key Responsibilities- Effectively function as a scientist, generating original technical ideas and research or development strategies.
- Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
- Independently responsible for project science within his/her area of expertise on one or more project teams leading the method development and validation for complex biologic therapeutics.
- Proactively seek out new information in the literature and incorporate this into individual projects as well as the overall program.
- Work in partnership with colleagues from Discovery, Process Chemistry/Engineering Formulation Development, and Characterization departments, among others.
Qualifications- Ph.D degree in Biochemistry, Analytical Chemistry, Pharmaceutical Sciences or a closely related discipline or MS degree with 8 years of experience.
- Qualification for Senior Scientist I: Ph.D. with 0-4 years of experience is required with relevant experience or MS with 8 years of experience.
- Qualification for Senior Scientist II: Ph.D. with 4+ years of experience is required with relevant experience or MS with 10 years of experience.
- Practical experience and strong knowledge in one or more of the following areas: protein/oligonucleotide HPLC, capillary electrophoresis, MALS, automation and/or spectroscopy for biologics.
- Previous cGMP or GLP experience and attention to detail in documentation.
- Demonstrated record of independent thought, creativity and scientific accomplishment (e.g. peer reviewed journal publications, patents).
- Must have a solid understanding of protein/oligonucleotide chemistry and biochemistry, particularly as related to biologics drug development.
- Strong data and time organization/management skills coupled with strong interpersonal and effective communication skills for facilitating collaborations with a demonstrated ability to lead cross functional process development teams.
- Effective writer and communication of research or other regulatory materials.
- Experience with analytical Multivariate Analytical Procedures development and/or validation a plus.
Leveling will be commensurate to experience.
Additional InformationApplicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
