Work ScheduleFirst Shift (Days)
Environmental ConditionsAdherence to all Good Manufacturing Practices (GMP) Safety Standards, Laboratory Setting
Job DescriptionSenior Scientist - ELISA / LBA / BiomarkerPosition:
Shift: Full-Time; Monday - Friday; 8am-5pm EST
ONSITE: This is a fully onsite role based at our customer's site in
(Boston, MA). We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.
Must be legally authorized to work in the United States without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
Key responsibilities:- Prior hands-on experience developing ligand binding assays for translational or clinical applications.
- Experience developing and validating assays, with working knowledge of assay validation expectations and fit-for-purpose principles.
- Design and execute method development activities for innovative biomarker assays intended for use as primary, secondary, or exploratory endpoints in clinical trials.
- Evaluate assay feasibility and strategies for the measurement of novel biomarkers in relevant biological matrices, including human biofluids and tissues.
- Collaborate with senior members of the Biomarkers group and cross-functional partners to develop, optimize, and implement high-quality biomarker assays.
- Apply knowledge of biomarkers, translational medicine, and assay validation principles to design robust assays suitable for clinical trial use and aligned with regulatory expectations, including FDA requirements.
- Perform mock validation experiments and contribute to generation of data packages supporting assay readiness.
- Support assay transfer activities to CROs and external laboratories, including technical handoff and troubleshooting as needed.
- Analyze, interpret, and clearly communicate experimental results to internal stakeholders and project teams.
- Present data at team and project meetings as needed
Education and Experience: - Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
- Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years')
- OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years')
- OR PhD
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities: - Method development and validation experience (Ligand binding assays, Immunoassays, ELISA)
- Biomarker Assay optimization and troubleshooting
- Western blot
- Protein labeling and quantification
- Molecular biology techniques
- Cell biology techniques
- Data interpretation and presentation
Working Environment: Below is listed the working environment/requirements for this role:
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds
Able to work in non-traditional work environments.
Able to use and learn standard office equipment and technology with
proficiency.
May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
BenefitsWe offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Compensation and BenefitsThe salary range estimated for this position based in Massachusetts is $95,000.00-$105,000.00.
This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
- A choice of national medical and dental plans, and a national vision plan, including health incentive programs
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement
- At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
- Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
- Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
