Job Description

The Nonclinical Drug Safety (NDS) division at our company is seeking a motivated and talented biomedical engineer or integrative systems scientist with experience in signal processing and/or computational modeling using physiologic signals to join our Safety & Exploratory Pharmacology group.

The Safety & Exploratory Pharmacology (SEP) collaborates with our discovery research, preclinical, and clinical development partners to identify and develop effective, safe therapeutics. To that end, SEP utilizes a purposeful blend of standard screening tools, regulatory-enabling assays, fit for purpose capabilities and forward-looking innovative solutions to understand potential major organ system pharmacodynamic risk to influence drug development strategy.

To enhance that mission, we are looking for a MS or early-career PhD level individual contributor that will complement existing areas, expand the teams expertise, and help drive future innovation. The successful candidate will have demonstrated experience in areas detailed below and will possess the attributes and interest in developing their career toward increasing levels of responsibility and independence within our team.

Key responsibilities will include:

• Analyzing physiologic signals to contribute to risk assessment evaluations and developing data visualizations for scientific exploration
• Building new in vivo analysis tools (signal processing, machine learning, AI) for nonclinical data and refining or developing new endpoints
• Working with external vendors to identify and incorporate potential solutions
• Collaborating with internal data science and IT teams to implement data tools
• Integrating new analysis workflows into SEP
• Contributing to SEP initiatives to develop and characterize novel alternative methods (NAMs) with in vitro scientists

QUALIFICATIONS:

Education:

• Bachelors (with 7+ years), Masters (with 4+ years) or Ph.D. in Biomedical Engineering, Bioengineering, Computational Biology, or related scientific field with relevant experience in the collection and computational analysis of physiologic signals (e.g. ECG, EEG, blood pressure) and a background in pharmacology, physiology, biology, biomedical sciences, or toxicology

Required Experience and Skills:

• Experience with nonclinical signal analysis
• Proficiency with programming tools (Python, MatLab, R) for physiological signal analysis, feature extraction, and/or development of computational models (including AI tools and workflows)
• Previous experience working with physiological, continuous, time-series data sets (including visualization, analysis, and/or interpretation)
• Motivation and enthusiasm to expand programming/analysis skill set and learn new software tools
• Ability to work within teams as a contributor and enable collaborations across departments that deliver current needs and future capabilities
• Ability to collaborate with both laboratory scientists and data scientists/IT specialists
• Excellent communication skills and ability to translate complex technical issues to laboratory scientists

Preferred Experience and Skills:

• Nonclinical signal analysis experience in cardiovascular, neuroscience, or respiratory endpoints
• Experience with statistical and data visualization tools and libraries
• Experience with cloud computing environments
• Previous exposure to data science best practices and reproducibility
• Prior experience working in a multidisciplinary environment within the Pharmaceutical Industry
• Willingness to influence safety pharmacology science through active participation in external consortiums, publications, and/or scientific presentations

#EligibleforERP

Required Skills:

Preferred Skills:

Current Employees apply

Current Contingent Workers apply

US and Puerto Rico Residents Only:

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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