BridgeBio Pharma, Inc.

Senior Scientist

BridgeBio Pharma, Inc.$152K — $180K *
US-AnywhereRemote in United States
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Statistical Genetics, Human Genetics, Computational Biology, or related field with 5+ years of industry experience, particularly in rare disease genetics.
  • Hands-on experience with UK Biobank and All of Us data, demonstrating understanding of their architecture and data types.
  • Extensive experience in QC, analysis, and interpretation of human genetics data including single-variant and gene-based association analyses.
  • Proficient in Python and experienced with AI-powered tools to enhance analytical productivity and reliability.
  • Experience with inferring disease incidence and prevalence from genetic data.

Responsibilities

  • Design and execute analyses of various traits in population cohorts to support research and partnership evaluations.
  • Integrate analyses of genetics and EHR data for target identification and biomarker discovery.
  • Collaborate with biology, clinical, and business teams to derive actionable insights from data.
  • Communicate findings through presentations and reports, contributing to scientific publications and conferences.

Benefits

  • Market-leading compensation with performance bonuses and equity options.
  • 401(k) plan with employer matching and employee stock purchase program.
  • Comprehensive health benefits with 100% employer-paid premiums for employees and dependents.
  • Flexible paid time off policy allowing for a healthy work-life balance.
  • Continuous career development through education and growth opportunities, including access to coaching and professional development resources.
Full Job Description
What You'll Do You will lead statistical genetics analyses of primarily population-scale genomics data to inform decisions about new business opportunities and advance internal development programs. Working independently in a dynamic, data-driven environment, you will leverage methods from multiple disciplines, including statistical inference, machine learning, and simulation frameworks, to extract insights and translate them into actionable recommendations. You will also contribute to building and maintaining the computational tools and infrastructure that enable streamlined, reproducible analyses across the team. Responsibilities - Design, execute, and interpret analyses of diverse quantitative and binary traits in large-scale population cohorts to support internal research programs and external opportunity evaluation (e.g., new program opportunities and partnership diligence) - Perform integrative analyses of human genetics and EHR data to enable target identification, biomarker discovery, and clinical development decisions - Collaborate closely with cross-functional stakeholders, including biology, clinical, and business development teams, to translate analytical findings into actionable insights - Communicate results clearly and effectively through internal presentations, written reports, and contributions to external scientific publications and conferences Where You'll Work This is a U.S.-based remote role with periodic travel (quarterly or as needed) to BridgeBio's San Francisco office or conference locations. Who You Are Required: - PhD in Statistical Genetics, Human Genetics, Computational Biology, or related disciplines with 5+ years of industry experience. Experience with rare disease genetics and translational research is strongly preferred. - Demonstrated hands-on experience working with UK Biobank and All of Us data, including a strong understanding of their data architecture and data types. Applicants must include brief descriptions of relevant projects in their resume - Extensive experience with QC, analysis, and interpretation of human genetics data (single-variant and gene-based association analyses using WES/WGS/array genotyping data) - Proficiency in Python and hands-on experience integrating AI-powered tools (e.g., Claude, Codex) into analytical workflows to improve productivity, reproducibility, and code quality across code generation, data analysis, and documentation, with appropriate validation of outputs. Preferred - Experience inferring disease incidence and prevalence from genetics data - Familiarity with large-scale human genomics databases (including but not limited to gnomAD, GTEx, 1000 Genomes, and TOPMed). Hands-on experience is strongly preferred - Experience supporting target validation and/or biomarker discovery efforts in a pharmaceutical or biotechnology setting. - Familiarity with multi-omics data types (e.g., transcriptomics, proteomics, epigenomics, chromatin accessibility); hands-on experience preferred. At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states. Salary $152,800-$180,000 USD As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. For Full-Time U.S Based Roles: Financial & Rewards - Market-leading compensation - 401(k) with employer match - Employee Stock Purchase Program (ESPP) - Pre-tax commuter benefits (transit and parking) - Referral bonus for hired candidates - Subsidized lunch and parking on in-office days Health & Well-Being - 100% employer-paid medical, dental, and vision premiums for you and your dependents - Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA) - Fertility & family-forming benefits - Expanded mental health support (therapy and coaching resources) - Hybrid work model with flexibility - Flexible, "take-what-you-need" paid time off and company-paid holidays - Comprehensive paid medical and parental leave to care for yourself and your family Skill Development & Career Paths: - People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility - We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching - We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

About BridgeBio Pharma, Inc.

BridgeBio Pharma, Inc. is a biotechnology company that focuses on developing medicines for genetic diseases. The company's pipeline includes over 20 development programs, including treatments for diseases such as achondroplasia, adrenoleukodystrophy, and cystinosis. BridgeBio Pharma, Inc. also has a subsidiary, Eidos Therapeutics, which focuses on developing treatments for transthyretin amyloidosis. The company was founded in 2015 and is headquartered in Palo Alto, California.
Learn more about BridgeBio Pharma, Inc.
Size
576 employees
Market Cap
$1 billion
Industry
Net Income
-$448.7 million
Founded
2014
Revenue
$8.2 million
NASDAQ

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