Genentech

Senior/Principal AI/ML Computational Scientist

Genentech$156K — $343K *
Healthcare
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in a quantitative discipline such as biomedical engineering, computer science, or statistics.
  • Strong background in image analysis, computer vision, and machine learning.
  • Proficiency in Python for scientific computing and data analysis.
  • Experience with deep learning frameworks like PyTorch or TensorFlow.
  • Demonstrated ability to develop computational methods for image-based analysis.
  • Strong quantitative and analytical skills.
  • Effective communication skills for cross-disciplinary collaboration.

Responsibilities

  • Develop and apply computational image-analysis methods using machine learning and deep learning.
  • Analyze digital pathology datasets to generate interpretable quantitative results.
  • Collaborate with pathologists and toxicologists to design analytical strategies.
  • Contribute to the creation of reusable computational workflows and research tools.
  • Perform data quality assessments and statistical analyses to support scientific decisions.
  • Evaluate and implement emerging computational approaches in digital pathology.
  • Communicate findings effectively to both technical and non-technical stakeholders.

Benefits

  • Relocation assistance available.
  • Opportunity to work in a highly collaborative and interdisciplinary environment.
Full Job Description

We are seeking a talented PhD-level senior AI/ML computational scientist to join the Digital Pathology group in Translational Safety. We develop computational solutions to biological questions posed by pathologists and toxicologists, with an emphasis on image analysis, machine learning, and deep learning approaches for digital pathology and related imaging data.

As part of our team, you will contribute to the development and implementation of image-analysis methods and pipelines using both classical and modern computational approaches. You will work closely with pathologists, toxicologists, and computational scientists to generate quantitative insights from image-based datasets and help advance pathology workflows in drug discovery and development.

Opportunity:

This role is well suited for a scientist who is excited to apply quantitative and computational methods to biomedical imaging in a highly collaborative, interdisciplinary environment.

As an integral member of our dynamic team, you will be:

  • Developing and applying computational image-analysis methods and pipelines using classical image processing, machine learning, and deep learning approaches.

  • Analyzing digital pathology and related imaging datasets to extract quantitative features, generate interpretable results, and support biologically relevant conclusions.

  • Collaborating closely with pathologists, toxicologists, and cross-functional scientists to understand project goals, design analytical strategies, and interpret findings in biological context.

  • Contributing to the development of reusable, well-documented computational workflows and research tools.

  • Perform data quality assessment, statistical analyses, and data visualization to support scientific decision-making.

  • Evaluating and implementing emerging computational approaches relevant to digital pathology and image analysis.

  • Communicating results clearly through presentations, written summaries, and discussions with technical and non-technical stakeholders.

  • Contributing to a collaborative, rigorous, and scientifically curious team environment.

Who You Are:

  • PhD in biomedical engineering, bioengineering, computer science, computational biology, bioinformatics, data science, statistics, computer vision, image analysis, or a related quantitative discipline; Senior Scientist level (0-2 years) Principal Scientist (3+ years of experience)

  • Strong background in image analysis, computer vision, machine learning, and deep learning.

  • Proficiency in Python for scientific computing and data analysis.

  • Experience with at least one deep learning framework such as PyTorch or TensorFlow.

  • Demonstrated ability to develop and implement computational methods or pipelines for image-based data analysis.

  • Strong quantitative, analytical, and problem-solving skills.

  • Strong written and verbal communication skills, and the ability to work effectively in cross-disciplinary teams.

  • Interest in applying computational approaches to biomedical imaging and translational safety questions.

  • Position leveling will be determined after the interview process.


Preferred Experience:

  • Experience with digital pathology, whole-slide image analysis, histology, microscopy, or other biomedical imaging data.

  • Experience with statistical analysis and data visualization.

  • Familiarity with version control and collaborative software development practices.

  • Familiarity with open-source or commercial image-analysis tools such as OpenSlide, QuPath, HALO, Visiopharm, or related platforms.

  • Experience working in high-performance computing or cloud computing environments.

  • Experience curating, organizing, or preparing image datasets for model development.

  • Experience working in collaborative research environments involving both computational and experimental scientists.


Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $156,200-$290,200 (Senior Scientist) and $185,200-$343,900 (Principal Scientist) . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

About Genentech

Genentech is a biotechnology company that develops and manufactures drugs for the treatment of serious medical conditions. The company was founded in 1976 and is headquartered in South San Francisco, California. Genentech's products include treatments for cancer, multiple sclerosis, and other diseases. The company is a subsidiary of Roche, a Swiss pharmaceutical company. Genentech has been recognized for its innovative research and development, and has received numerous awards for its contributions to the biotechnology industry.
Learn more about Genentech
Size
14,000 employees
Industry
Founded
1976

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