Roche

Scientist 2, T Cell Therapy

Roche$87K — $161K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • B.S. degree with 1-5 years experience in Immunology, Oncology, or related field OR M.S. degree with 1-3 years relevant experience.
  • Practical experience with cell-based assays design, development, validation, and execution.
  • Experience with flow cytometry and immune cell-based functional assays.
  • Proven skills in primary immune cell isolation and culture, and CAR-T cell generation.
  • Strong ability to work independently and collaborate within project teams.
  • Record of publications demonstrating expertise in the field.
  • Excellent communication, teamwork, and organizational skills.

Responsibilities

  • Support the screening and characterization of CAR-T and antibody therapeutics.
  • Develop, validate, and execute high-throughput cell-based assays.
  • Characterize CAR-T cell and antibody activity in vitro.
  • Participate in lead-finding and optimization efforts for T cell therapies.
  • Collaborate with multi-disciplinary project teams across various departments.
  • Present research findings to project teams and senior management.
  • Contribute to scientific publications and present at conferences.

Benefits

  • On-site work based in South San Francisco.
  • Engagement with a multi-disciplinary team.
  • Opportunities for publication and presentation at scientific forums.
Full Job Description
Scientist 2, T Cell Therapy

The Opportunity

We have an opening for a talented Scientist 2 to join our Biochemical and Cellular Pharmacology Department within Genentech’s Research and Early Development (gRED) organization.

The successful candidate will support in vitro screening & functional characterization of CAR-T and antibody therapeutics for oncology and immunology disease areas, by participating in the development, validation and execution of high-throughput cell-based assays to characterize CAR-T cell and antibody activity in vitro and support lead-finding/optimization efforts.

In addition, the candidate will function as part of a multi-disciplinary project team that will coordinate with Oncology, Immunology, Cell Therapy, Antibody Engineering, and Protein Chemistry groups to advance T cell therapies. The candidate will have the opportunity to present their work to project teams and senior management and is expected to contribute to publications and present at scientific conferences.

This position is based in South San Francisco, on site.

Who You Are (Required)

  • B.S. degree with 1-5 years of experience in Immunology, Oncology, Cell Biology, Biochemistry, or a related field OR

  • M.S. degree with 1-3 years of relevant immunology/immuno-oncology and/or cell biology experience in academia, biotechnology and/or pharmaceutical industry.

  • Practical experience in the design, development, validation and execution of cell-based assays.

  • Experience with flow cytometry, immune cell-based functional assays, primary immune cell isolation and culture, and CAR-T cell generation.

  • Ability to work independently to design, execute, and interpret experiments, and also collaborate with project teams.

  • Record of publications that demonstrates expertise.

  • Excellent teamwork, communication, time management, and organizational skills.

Additional preferred skills

A strong foundation in immunology and hands-on expertise in immune cell assays.

Familiarity with iPSC derived immune cells is a plus.

Experience with Luminex, Incucyte, and/or xCELLigence.

Familiarity with automated or semi-automated instrumentation.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on California is 87 000,00 - 161 600,00 USD Annual Annual.Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.A discretionary annual bonus may be available based on individual and Company performance.This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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