Revolution Medicines

Senior Manager, Portfolio Management & Operations

Revolution Medicines$164K — $205K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • B.Sc. in a relevant discipline with 5+ years of experience in CMC or project management in life sciences.
  • Strong analytical skills with experience in forecasting and resource modeling.
  • Ability to connect data insights to actionable business recommendations.
  • Proven capacity to influence across departments and establish productive relationships.
  • Exceptional communication skills for presenting complex information succinctly.
  • Demonstrated capability to navigate and deliver in fast-paced, changing environments.
  • Strong project management skills to align priorities and execute under uncertainty.

Responsibilities

  • Partner with leadership to support portfolio planning and strategic decision-making.
  • Create analyses that inform prioritization and resource allocation.
  • Facilitate cross-functional planning and governance to ensure stakeholder alignment.
  • Develop metrics and dashboards for visibility into portfolio performance and risks.
  • Support budgeting and long-term planning with data analysis and insights.
  • Lead strategic initiatives to improve business processes and effectiveness.
  • Apply structured problem-solving to address cross-functional challenges.

Benefits

  • Competitive cash compensation and equity awards.
  • Strong benefits package including health and wellness programs.
  • Significant learning and development opportunities.
  • Flexible work environment with hybrid options.
Full Job Description
The Opportunity:

Revolution Medicines is seeking a motivated individual with experience in CMC, project and portfolio management, and/or life sciences management consulting to play a critical role within the Portfolio Management group of the Pharmaceutical Development and Manufacturing (PDM) organization. This position will serve as a key business partner supporting portfolio analytics, governance operations, resource and cost management, and strategic cross-functional initiatives. The role will partner closely with cross-functional stakeholders to drive execution of critical business processes, support decision-making, and improve organizational effectiveness across a growing portfolio of discovery, development, and commercial programs.

Responsibilities:
  • Partner with PDM leadership and cross-functional stakeholders to support portfolio planning, business operations, and strategic decision-making across the organization.
  • Develop analyses, insights, and recommendations that enable effective prioritization, resource allocation, risk management, and execution of business objectives.
  • Drive cross-functional planning and governance activities by facilitating stakeholder alignment, supporting decision-making forums, and ensuring effective follow-through on key actions and commitments.
  • Develop and maintain portfolio reporting, metrics, dashboards, and other decision-support tools to provide visibility into portfolio performance, organizational capacity, risks, and opportunities.
  • Support budgeting and long-range planning activities through data analysis, scenario modeling, and business insight generation.
  • Lead or contribute to strategic initiatives and operational excellence efforts aimed at improving business processes, organizational effectiveness, and scalability.
  • Apply structured problem-solving and analytical approaches to address complex cross-functional challenges and support informed decision-making.
  • Build strong partnerships across PDM and adjacent functions to promote transparency, alignment, and effective execution of key priorities.
  • Prepare and deliver clear, concise, and compelling communications, presentations, and recommendations for audiences ranging from working teams to senior leadership.

Required Skills, Experience and Education:
  • B.Sc. in a scientific, engineering, business, or related discipline, with 5+ years of experience within a CMC, Project and Portfolio Management, and/or life sciences management consulting organization.
  • Robust analytical and problem-solving skills with experience in scenario planning, forecasting, resource modeling, and business analytics; demonstrated ability to translate analytical insights into executive-level communications.
  • Strong scientific and business acumen with the ability to connect data, portfolio priorities, resource constraints, and organizational objectives into actionable recommendations.
  • Demonstrated intellectual curiosity and learning agility, with a willingness to quickly develop expertise in new business processes, functional areas, and technical domains.
  • Ability to influence without authority and build productive working relationships across functions and organizational levels.
  • Exceptional communication and storytelling skills with the ability to synthesize complex information into clear, concise, and compelling recommendations for senior leadership.
  • Demonstrated ability to balance strategic thinking with operational execution and deliver results across complex cross-functional initiatives.
  • Demonstrated success operating in fast-paced, dynamic environments with evolving priorities and ambiguity.
  • Proven track record of taking ownership, identifying opportunities for improvement, and proactively driving solutions with minimal direction.
  • Strong project management and facilitation skills with the ability to drive alignment, manage competing priorities, and execute effectively in ambiguous environments.

Preferred Skill:
  • Advanced degree in a scientific, engineering, business, or related discipline.
  • PMP or similar project management certification.

#LI-CT1 #LI-Hybrid

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$164,000-$205,000 USD

About Revolution Medicines

Revolution Medicines is a clinical-stage precision oncology company focused on developing targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on RAS and mTOR signaling pathways. The company's proprietary platform enables the discovery and development of small molecules that bind covalently to proteins. Revolution Medicines was founded in 2014 and is headquartered in South San Francisco, California.
Learn more about Revolution Medicines
Size
201 employees
Market Cap
$2.1 billion
Industry
Net Income
-$108.1 million
Revenue
$42.9 million
NASDAQ

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