This role is considered On-Site.
Overview The Senior Manager, Global Planning is a key member of the Supply Chain organization responsible for the planning and oversight of Drug Substance and Drug Product manufacturing for the early stage pipeline. This position works closely with key stakeholders including: Program Teams, Process Sciences, CMC, Internal and External Manufacturing, Quality Assurance (QA), Global Logistics and Regulatory Affairs, to ensure seamless supply of Clinical Trial Material. This role will also be a key contributor to the Global CS&OP process with development of the Early Stage and Partner S&OP Process. A successful candidate will be skilled at understanding the Clinical Supply and Operations planning process and the challenges/timelines of early stage development. In addition, a successful candidate will demonstrate the ability to work indepdently with only minimal guidance on highly complex situations.
This role follows a hybrid work model, with an expectation of being on-site in our
Cambridge, MA office a minimum of
two days per week. Additional in-person presence may be required based on business needs, team meetings, or project demands.
Key Responsibilities- Key contributor to clincal supply and operations planning monthly team meeting (CS&OP)
- Contribute and advise on Partner Sales and Operation Demand Reviews.
- Work cross-functionally to develop scenario plans and strategies that result in production plans that meet program, capacity, and budget requirements.
- Leads and supports other in the group to provide strategic planning and execution recommendations.
- Collaborate with external partners to ensure Drug Substance and Drug Product supply needs are met in line with contractual obligations.
- Develop short and long term manufacturing plans using clinical development plans from program management and CMC.
- Partner with CMC, Process Sciences, Program Team, QA, QC, Finance and Materials Management to ensure material availability is in line with clinical program timelines and budget.
- Troubleshoot and identify root causes, and suggest solutions to meet project objectives.
- Develops Annual Long Range Manufacturing Plans based on available information, highlighting areas of constraint.
- Uitlize and oversee SAP master data integrity to ensure inventory and order management is accurate and precise.
- Build strong relationships and communication with all functions to ensure information is accurate for planning purposes.
Qualifications- B.S. in Business, Supply Chain, Engineering or science-related discipline. Advanced degree preferred.
- A minimum of 5 years of relevant experience, 7 years preferred, in a Manufacturing or Supply Chain role with experience in Production, Planning, or Scheduling.
- Excellent math and computer skills required, including Microsoft Office/Excel/PowerPoint.
- Good knowledge of computerized production and inventory control systems (SAP) and documentation practices.
- Demonstrated ability to manage multiple priorities against ambitious timelines. Strong project management ability.
- Exceptional communication skills and ability to communicate to multiple levels within company. Ability to present complex information to all levels of the organization.
- Strong problem-solving skills and ability to work cross-functionally as critical member of site team.
- Experience with site capacity planning and/or global product supply planning and knowledge of Biotech, Pharmaceutical Sales & Operations Planning processes.
- ERP planning experience a plus
About Alnylam: Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.
Our culture: Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2023 for the third consecutive year, one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law.
