Senior Manager FP&A

Monte Rosa Therapeutics, Inc

• $130K — $155K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Finance, Accounting, Economics, or a related quantitative field.
  • 7–10+ years of progressive FP&A, corporate finance, or accounting experience.
  • Demonstrated ownership of multiple full budget and forecast cycles for significant cost centers.
  • Advanced Excel and financial modeling skills, capable of building flexible models from scratch.
  • Strong command of accrual accounting and the month-end close process.
  • Preferred experience in biotech, pharma, or life sciences, especially at a clinical-stage company.
  • Hands-on experience with NetSuite and EPM/planning tools, plus familiarity with public company reporting.

Responsibilities

  • Own the annual operating plan, quarterly reforecasts, and long-range planning for assigned areas.
  • Build and maintain driver-based models for various financial elements including headcount and external spend.
  • Prepare monthly and quarterly reporting packages with variance analysis and forward-looking commentary.
  • Contribute to cash forecasting, burn analysis, and runway management, supporting financing planning and Board materials.
  • Build financial models for contracts, collaborations, and resource allocation evaluations.
  • Model headcount plans, compensation cycles, and payroll/benefits forecasts in collaboration with People Experience & Operations.
  • Improve FP&A processes and reporting templates, ensuring compliance with internal controls and audit requests.

Benefits

  • High-visibility role with exposure to both scientific and corporate functions.
  • Opportunity to contribute to the annual planning cycle and Board-level reporting.
  • Broad scope of responsibilities, allowing for a comprehensive understanding of the company.
  • Collaborative environment working directly with department leaders.
  • Potential for professional growth in a dynamic biotech setting.
Full Job Description
Overview

We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans.

This is a broad, high-visibility role with exposure to both our scientific organization and our corporate functions. You will be a core contributor to the annual planning cycle, quarterly reforecasts, monthly close, cash and runway analysis, and Board-level reporting. The scope is intentionally wide — we are looking for someone who wants to understand how the whole company works, not just one slice of it.

Responsibilities

Operating plan and forecasting: Own the annual operating plan, quarterly reforecasts and long-range plan for assigned areas.

Driver-based modeling: Build and maintain driver-based models for headcount, personnel costs, external spend, consumables, capital and allocations.

Variance analysis and reporting: Prepare monthly and quarterly reporting packages with budget-versus-actual variance analysis. Include forward-looking commentary on the full-year outlook.

Cash and runway modeling: Contribute to cash forecasting, burn analysis and runway management. Support financing planning, Board materials, budget presentations and external operating expense guidance.

Contract and investment modeling: Build financial models and decision support for CRO/CDMO and vendor contracts, collaborations, capital equipment, software and facilities. Evaluate resource allocation trade-offs across programs, platforms and infrastructure.

Headcount and compensation modeling: Model headcount plans, compensation cycles, recruiting plans and payroll/benefits forecasts with People Experience & Operations.

Month-end close and expense accounting: Work with Accounting on accruals, reclasses and spend validation. Check that expense classification follows policy and external reporting requirements.

Systems, controls and process: Improve FP&A processes, reporting templates and self-service reporting in NetSuite and planning tools. Support internal controls, SOX-readiness and audit requests on budgeting and forecasting.

Qualifications

Education: Bachelor's degree in Finance, Accounting, Economics or a related quantitative field.

Experience: 7–10+ years of progressive FP&A, corporate finance or accounting experience.

Budget and forecast ownership: Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders.

Modeling: Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet.

Accounting: Strong command of accrual accounting and the month-end close process.

Preferred biotech and systems background: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers. Also hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting).

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