Amazon

Senior Manager, Applied Science

Amazon$218K — $295K *
Enterprise Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • PhD or Master's in Computer Science, Machine Learning, or related field, or equivalent applied research experience
  • 10+ years of applied science experience, including 3+ years managing teams
  • Experience setting research direction and strategy across multiple teams
  • Deep expertise in modern ML, including LLMs/foundation models and evaluation methodology
  • Track record of delivering complex research initiatives from concept through production in enterprise environments

Responsibilities

  • Build and lead a high-performing applied science team
  • Own the science strategy for measuring agent and human-AI team performance
  • Define and drive high-leverage research directions
  • Translate scientific findings into scalable products
  • Engage with leadership and customers on scientific matters
  • Set long-term scientific vision and research roadmap
  • Direct research on innovative, intricate problems

Benefits

  • Health insurance (medical, dental, vision, prescription, life insurance, etc.)
  • 401(k) matching
  • Generous paid time off
  • Parental leave
  • Adoption and Surrogacy Reimbursement coverage
  • Employee Assistance Program and Mental Health Support
Full Job Description
We are seeking a Senior Manager, Applied Science to build and lead the science organization across Agentic WorkSpaces. This is a foundational leadership role spanning the full portfolio - Personal, Applications, and Core, and the agentic surfaces (WS4Builders and WorkSpaces for Agents). You will hire, grow, and lead a team of applied scientists who define how we measure and improve the performance of AI agents and human-AI teams. A core part of the role is defining the science agenda itself - identifying which problems are most worth solving and where the highest-leverage bets lie. Directions worth exploring might include Organizational Intelligence (turning institutional knowledge into agent-consumable skills), AI Agent Experience / AiAX (agent observability and autonomous remediation), and contextual, behavioral security that adapts enforcement in real time for human and agent sessions - but these are illustrative examples, not a fixed roadmap, and many other directions are possible. You and your team will define which ones we pursue. The problems your team will solve do not have established industry patterns. You will set the scientific direction and build the team that determines how AI agents and people perceive, reason about, and act reliably within computing environments at enterprise scale.

What You Will Do

Build and lead the applied science team. Hire, develop, and retain a high-caliber team of applied scientists spanning the Agentic WorkSpaces portfolio. Set the bar for scientific talent, create the growth paths, and build the culture that makes AAWS a destination for the best agent and human-AI researchers.

Own the science strategy across the portfolio. Direct the research agenda for how we measure and improve agents and human-AI teams: the benchmarks, task suites, and metrics (accuracy, cost-per-task, task completion, productivity) that turn subjective "it works" judgments into rigorous, reproducible measurement that gates what we ship.

Define and drive high-leverage research directions. Work with your team to identify the problems most worth solving and shape the science agenda. Directions worth exploring might include how agents combine deterministic tool use (MCP) with visual reasoning from computer use; Organizational Intelligence and workflow learning (learning from expert recordings, voice annotations, and SOPs); and AI Agent Experience / AiAX (detecting when agents are stuck or degrading productivity and autonomously remediating) - these are illustrative starting points, and your team will weigh them against many other possibilities.

Translate science into shipped product. Partner with engineering, product, and program leaders to move models, evaluation, and learning systems from prototype into a decade-old production service operating at massive scale, without compromising the reliability that customers depend on.

Represent science in leadership and to customers. Be the scientific voice in org-level planning and roadmap decisions across AAWS, and engage directly with enterprise customers on how agent performance, safety, and human-AI productivity are measured and earned.

Key job responsibilities

Build and lead the applied science team. Hire, develop, and retain a high-caliber team of applied scientists spanning the Agentic WorkSpaces portfolio. Set the bar for scientific talent, create the growth paths, and build the culture that makes AAWS a destination for the best agent and human-AI researchers.

Own the science strategy across the portfolio. Direct the research agenda for how we measure and improve agents and human-AI teams: the benchmarks, task suites, and metrics (accuracy, cost-per-task, task completion, productivity) that turn subjective "it works" judgments into rigorous, reproducible measurement that gates what we ship.

Define and drive high-leverage research directions. Work with your team to identify the problems most worth solving and shape the science agenda. Directions worth exploring might include how agents combine deterministic tool use (MCP) with visual reasoning from computer use; Organizational Intelligence and workflow learning (learning from expert recordings, voice annotations, and SOPs); and AI Agent Experience / AiAX (detecting when agents are stuck or degrading productivity and autonomously remediating) - these are illustrative starting points, and your team will weigh them against many other possibilities.

Translate science into shipped product. Partner with engineering, product, and program leaders to move models, evaluation, and learning systems from prototype into a decade-old production service operating at massive scale, without compromising the reliability that customers depend on.

Represent science in leadership and to customers. Be the scientific voice in org-level planning and roadmap decisions across AAWS, and engage directly with enterprise customers on how agent performance, safety, and human-AI productivity are measured and earned.

Set the long-term scientific vision and team strategy: Define what best-in-class agent performance, evaluation, and learning look like across Agentic WorkSpaces - for computer-using agents and human-AI teams alike. Chart a multi-year research roadmap, and build the team and plan to deliver it. Secure buy-in from VP-level leadership.

Hire and grow scientific talent: Own recruiting, calibration, development, and retention for the science team. Mentor scientists toward senior and principal scope, and raise the scientific bar across the organization.

Direct research on highly ambiguous, novel problems: Guide the team through foundational challenges in agent perception, reasoning, evaluation, reliability, and human-AI collaboration - problems where neither the approach nor the success criteria are pre-defined.

Drive cross-organizational alignment: Work across partner teams (AgentCore, Bedrock model teams, Identity, Security, the MCP ecosystem) and across the Applied AI Solutions product portfolio, with product and engineering leadership, to ensure scientific decisions compose into a coherent product.

Deliver measurable business impact: Ensure your team's research translates to customer outcomes: higher task accuracy, lower cost-per-action, faster time-to-production, measurable productivity for human-AI teams, and the trust that lets enterprises scale agent workflows.

Establish scientific rigor and operational excellence: Set the standard for experimentation, evaluation, and reproducibility, and the mechanisms that keep the science organization productive and accountable.

Advance the state of the art: Enable and champion contributions to the external technical community through publications, patents, and open-source work that position AWS as the leader in the science of secure agent-computer interaction and human-AI teamwork.

BASIC QUALIFICATIONS

- PhD or Master's in Computer Science, Machine Learning, or a related field, or equivalent applied research experience

- 10+ years of applied science experience, including 3+ years managing and growing teams of scientists

- Experience setting research direction and strategy across multiple teams and organizations

- Deep expertise in modern ML, including LLMs / foundation models and evaluation methodology

- Track record of delivering complex, ambiguous research initiatives from concept through production in enterprise environments

PREFERRED QUALIFICATIONS

- Experience leading science teams working on AI agents, tool use, computer-use / GUI-grounded agents, or autonomous systems

- Experience building science teams from an early stage, including hiring at senior and principal levels

- Experience designing benchmarks, evaluation harnesses, and metrics for non-deterministic or agentic systems

- Experience with agent safety, grounding, guardrails, or reliability for LLM-based systems

- Familiarity with enterprise constraints: security, auditability, and compliance frameworks (NIST, SOC2, FedRAMP, HIPAA)

- A record of scientific leadership evidenced by publications, patents, or open-source contributions

- Experience influencing technical direction at VP+ level in a large technology organization

The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.

USA, NY, New York - 240,600.00 - 325,500.00 USD annually

USA, WA, Seattle - 218,800.00 - 295,900.00 USD annually

About Amazon

Audible is a provider of spoken audio information and entertainment , on the Internet. They provide premium spoken audio content, such as audio versions of books and newspapers and radio programs, that is delivered over the Internet and played back on personal computers and hand-held electronic devices. The Audible service allows consumers to purchase and download their content from their Website, store it in digital files and play it back on personal computers and electronic devices. More than 15,000 hours of audio content are available on their Web site, including audio versions of books, periodicals and radio programs. Several manufacturers have agreed to support and promote the playback of their content on their hand-held audio-enabled electronic devices.

Amazon Careers

Joining Amazon presents an unparalleled opportunity to become part of a vibrant team pushing the boundaries of innovation and growth in the global marketplace. As a leader in e-commerce, technology, and logistics, Amazon offers a variety of job opportunities that cater to a range of skills and professional interests. Work You’ll Do At Amazon, every day is an opportunity to collaborate with the brightest minds in technology and business to redefine what’s possible. Whether you’re interested in software development, marketing, human resources, or customer service, Amazon has a position waiting for you. Transform the way the world shops and innovates with our diverse and inclusive team. Amazon is not just a company; it’s a community where you can drive real change and contribute to projects impacting millions globally. Lead with Innovation and Leadership Amazon is the perfect place to enhance your leadership and innovation skills. Our culture encourages pushing the envelope and imagining the unimaginable. Here, you will lead projects that challenge the status quo and define new industry standards. Work with a team that values diversity and is committed to creating an inclusive environment. Our leadership is focused on harnessing the collective power of unique perspectives to foster growth and innovation. Explore Amazon’s Employment Benefits Amazon’s commitment to its employees extends beyond just career growth. We offer competitive benefits, including health care, parental leave, and diversity training, ensuring that our team not only excels professionally but also enjoys well-being and security. Internship and Networking Opportunities Start your career with an Amazon internship and gain hands-on experience that matters. Our internships provide a gateway to full-time employment and an opportunity to network with professionals across various sectors of the company. Future-Proof Your Career With Amazon, your career path is filled with numerous opportunities for advancement. Our learning and development programs are designed to nurture your professional growth and keep you at the forefront of industry trends. Stay Connected Join Our Team Discover the job opportunities at Amazon that match your skills and interests. We are constantly on the lookout for passionate, curious, and innovative team players ready to make a difference. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Job Alert Emails Customize your subscription to receive job alerts, the latest news, and insider tips tailored to your preferences. Explore the exciting and rewarding career opportunities that await at Amazon. Amazon is more than just a company—it’s a platform for building a promising future. Whether you’re starting or looking to advance your career, Amazon offers the resources, support, and network you need to succeed. Join us, and be a part of our continuing mission to be Earth's most customer-centric company.
Learn more about Amazon
Size
1,608 employees
Market Cap
$832.6 billion
Industry
Net Income
$21.3 billion
Founded
1994
5 Year Trend
+28.1%
Revenue
$386 billion
NASDAQ

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