McKesson

Senior IT Architect (Enterprise Applications / Clinical Platforms)

McKesson$133K — $221K *
Healthcare
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 7+ years of experience in software engineering, including 4+ years in architecture across multiple systems.
  • Strong enterprise integration architecture skills with REST APIs and event-driven messaging.
  • Proven technical expertise in cloud-native architectures (microservices, containers) on Azure, AWS, or GCP.
  • Experience with designing and operating large-scale multi-tenant services emphasizing reliability and security.
  • Exceptional communication and stakeholder-management skills to influence decisions.

Responsibilities

  • Drive architecture for cross-system interoperability and integration capabilities.
  • Collaborate with teams to translate requirements into architectural designs and delivery plans.
  • Establish architecture standards and reference implementations for APIs and integration patterns.
  • Evaluate solution options and communicate trade-offs to stakeholders.
  • Provide technical guidance to mentor engineers and architects.
  • Define and govern integration reference architectures including event-driven workflows.
  • Collaborate with security teams to ensure secure integration approaches.

Benefits

  • Work in a transformative oncology-focused environment.
  • Opportunity to influence multiple engineering teams and strategic initiatives.
  • Engagement with cutting-edge technologies in cloud-native architecture.
  • Chance to grow within a company dedicated to healthcare innovation.
Full Job Description

Role Summary

Ontadais an oncology data science and technology business dedicated to transforming the fight against cancer. We specialize in real-world data and evidence generation that accelerates life science research, clinical technologies that support community providers with precise care, and provider engagement channels that enable education and insights.

We are hiring anIT Architect to define and drive cloud-native integration architecture acrossOntadaproducts and partner ecosystems. This role owns solution and platform architecture for API-led connectivity, event-driven integration, and secure data exchange—ensuring our systems are scalable, reliable, observable, and straightforward to evolve. Familiarity with healthcare interoperability standards (HL7/FHIR, including SMART on FHIR) is a plus for certain partner pathways, but the primary focus is strong enterprise-architecture fundamentals applied to modern cloud-native integration models.

Success in this role is measured by the clarity and adoption of your reference architectures and standards, the reliability and scalability of the integration ecosystem you enable, and your ability to influence decisions across multiple initiatives while mentoring and elevating engineering teams. Familiarity with AI/ML and NLP capabilities used in products (e.g., LLM-enabled workflows, retrieval patterns, evaluation, and governance) is a plus asOntadaexpands intelligentexperiences, butis not the core requirement.

Technical Environment

Cloud-Native Integration:API-led connectivity, event-driven architecture, pub/sub, schema management, idempotency, retries, backpressure
APIs:RESTful services,OpenAPI/Swagger, API gateways, versioning and contract-first design
Messaging:Kafka (or equivalent), queues/streams, event schema design
Platform Patterns:Microservices, containerization (Docker), service discovery, configuration management; service mesh (where applicable)
Data & Performance:Oracle and relational databases; Redis (caching); Elasticsearch; analytics/pipelines (e.g., Databricks)
Interoperability (nice to have):HL7v2, FHIR (R4+), SMART on FHIR, OAuth2/OIDC, C-CDA
Observability:Logging, metrics, distributed tracing (e.g., Dynatrace)
Cloud & Platforms:Azure, AWS, GCP, Cloud Foundry
Engineering Practices:CI/CD, automated testing, code reviews, architecture documentation

Key Responsibilities

Architecture Leadership & Strategy

  • Drive architecture for interoperability and integration capabilities across systems, services, and product offerings.

  • Partner with Product Owners, Sales, Business Analysts, Quality Assurance, and Project Management to translate functional and non-functional requirements into target architectures and delivery plans.

  • Define architecture standards, reference implementations, and guardrails for APIs, integration patterns, security, and operational readiness.

  • Evaluate solution options and drive alignment across stakeholders; communicate tradeoffs, risks, and recommendations to technical and non-technical audiences.

  • Providetechnical guidance to coach, motivate, and develop engineers and architects.

Cloud-Native Integration Architecture

  • Define and governintegrationreference architectures across APIs, events, and asynchronous workflows (request/response, pub/sub, choreography vs. orchestration).

  • Establish platform patterns and guardrails for API gateways, service-to-service communication, schema/version management, and contract testing.

  • Design for resiliency and performance using proven patterns (timeouts, retries, circuit breakers, bulkheads, idempotency, caching) andalignto SLOs/SLAs.

  • Guideevent-driven integration (e.g., Kafka or equivalent) with well-defined event schemas, lifecycle management, and operational controls.

  • Collaborate with security and platform teams to ensure secure-by-default integration approaches (OAuth2/OIDC, least privilege,secretsmanagement, threat modeling).

Healthcare Interoperability (Optional) & Partner Integrations

  • When applicable, drive design for healthcare data exchange leveraging HL7v2 and/or FHIR (R4+), including SMART on FHIR, to enable integrations with EMRs and partner systems.

  • Partner with domain SMEs and external stakeholders to define interoperability expectations (security, conformance, and onboarding) and ensure integrations are scalable and supportable.

  • Define API contracts, versioning strategy, and error taxonomy to enable predictable integrations for internal and external consumers.

  • Partner with engineering teams to implement and evolve reusable integration components, adapters, and accelerators that reduce time-to-integrate.

Operational Excellence & Production Ownership

  • Collaborate with engineering in release, sprint, and project planning to ensure delivery commitments are tracked and met across the SDLC.

  • Demonstrate strong architectural ownership in production operations to address customer needs for support, issue analysis, enhancements, and corrective actions.

  • Evolve software systems, infrastructure, and architecture to support growth, SLAs, availability, and continued operation.

  • Drive operational readiness practices including observability, runbooks, incident response, and post-incident improvements.

  • Resolve technical problems, issues, and escalations across delivery teams and project activities.

AI Enablement (Preferred)

  • Partner with product and engineering teams toidentifyand deliver AI-enabled capabilities, from discovery and design through deployment, monitoring, and continuous improvement.

  • Guide architecture patterns for integrating model services into cloud-native systems (APIs, events, data pipelines) withappropriate security, privacy, and compliance controls.

  • PromoteMLOps/LLMOpspractices (versioning, CI/CD, automated testing, observability, rollback) and responsible AI governance.

  • Collaborate on evaluation approaches to ensure AI features are reliable and safe for production use.

Minimum Requirement

Degree or equivalent and typically requires 7+ years of relevant experience.

Education

Bachelor27s degree in computer science, Software Engineering, Information Systems, or equivalent practical experience.

Critical Skills

  • 7+ years of software engineering experience, including 4+ yearsinarchitecture (solution, platform, or enterprise) with ownership across multiple systems.

  • Strong enterprise integration architecture skills across REST APIs, event-driven messaging, and secure data exchange patterns.

  • Strong technical fundamentals in cloud-native architecture (microservices, containers, resiliency patterns, observability) on Azure, AWS, or GCP.

  • Experience designing andoperatinglarge-scale, multi-tenant services with reliability, scalability, and security best practices.

  • Ability to drive cross-functional technical decisions, mentor engineers/architects, and communicate clearly through documentation and design reviews.

  • Strong communicationand stakeholder-management skills, witha track recordof influencing cross-team decisions through documentation and design reviews.

  • Nice tohave:familiarity with HL7/FHIR and/or willingness to learn quickly as needed for partner integrations.

Preferred Skills

  • Optional/nice tohave:hands-on experience with FHIR (profiles, implementation guides, SMART on FHIR) and/or HL7v2, including conformance and integration testing.

  • Experience integrating with multiple EMRs and partner ecosystems; familiarity with common healthcare workflows and data exchange constraints.

  • Hands-on experience with microservices frameworks (e.g.,Springor equivalent) and API management practices.

  • Experience with messaging and integration platforms (Kafka, service bus/queues, stream processing) and caching technologies (e.g., Redis).

  • Experience with platform engineering patterns such as service mesh, policy-as-code, and automated architecture validation in CI/CD.

  • Experience with observability platforms (e.g., Dynatrace) and production operations best practices.

  • AI/ML product delivery experience (LLM-enabled workflows, evaluation, and responsible AI governance).

  • Experience with Elasticsearch and/or analytics platforms (e.g., Databricks).

What Success Looks Like

At 6 Months

  • You haveestablished</

About McKesson

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry. The Company operates in two segments. The McKesson Distribution Solutions segment delivers ethical drugs, medical-surgical supplies and equipment and health and beauty care products throughout North America. This segment also provides specialty pharmaceutical solutions for biotech and pharmaceutical manufacturers, sells financial, operational and clinical solutions for pharmacies (retail, hospital, long-term care) and provides consulting, outsourcing and other services. The McKesson Technology Solutions segment delivers enterprise-wide clinical, patient care, financial, supply chain, strategic management and software solutions. In July 2011, the Company acquired Portico Systems from Safeguard Scientifics, Inc. On March 25, 2012, it acquired the independent banner and franchise businesses of Katz Group Canada Inc. McKesson Distribution Solutions delivers pharmaceuticals to retail pharmacies and institutional providers like hospitals and health systems. They operate pharmaceutical distribution centers across the country, serving customers in all 50 states. They also deliver a comprehensive offering of health care products, technology, equipment and related services to the alternate site market, including physician offices, surgery centers, long-term care facilities and home care businesses across the country. McKesson is currently the largest pharmaceutical distributor in North America. McKesson also operates McKesson Canada and has an equity holding in Nadro, a leading distributor in Mexico.

McKesson Careers

Join McKesson, a leading global healthcare company, and be part of a team that is redefining the future of healthcare. With a variety of job opportunities available, McKesson is the perfect place to advance your career, whether you're a seasoned professional or just starting out. Work You’ll Do At McKesson, we are committed to improving care in every setting—one product, one partner, one patient at a time. We’re seeking talented professionals to join our team and contribute to a culture of innovation, diversity, and leadership. Our employees are driven by a deep sense of purpose and a desire for continuous growth and improvement. Empower Your Future in Healthcare With positions ranging from internships to leadership roles, McKesson offers unparalleled employment opportunities to develop your skills and advance your career. Our commitment to diversity training ensures that all team members have the opportunity to thrive. Join a team where your skills will be honed, your professional growth will be supported, and where you can genuinely see the difference you make in the lives of patients around the world. Innovative Work Environment McKesson is at the forefront of healthcare innovation. Our team is constantly exploring new ways to improve patient outcomes and streamline care processes. This commitment to innovation is what sets us apart and what makes McKesson an exciting place to work. Career Development and Benefits McKesson believes in nurturing the potential of its employees through robust career development programs and comprehensive benefits designed to support your life and well-being. From leadership training to health and wellness benefits, we ensure our team members are equipped to meet their professional and personal goals. Explore Job Opportunities Whether you’re looking for an internship to kickstart your career, or a senior position to utilize your extensive experience, McKesson offers a range of opportunities. Explore our open positions and find where you can make a difference at McKesson. Stay Connected Join Our Team Search for open positions that match your skills and interests. We are looking for passionate, curious, and solution-driven team players who are ready to take the next step in their careers. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Networking and Professional Growth At McKesson, networking and professional growth are part of our everyday environment. We encourage our employees to connect, share, and learn from each other to foster personal and professional development. Job Alert Emails Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await you at McKesson. Join McKesson today and be part of a team that is dedicated to shaping the future of healthcare.
Learn more about McKesson
Size
58,000 employees
Market Cap
$53.7 billion
Industry
Net Income
-$4.1 billion
Founded
1833
5 Year Trend
+5.9%
Revenue
$237.6 billion
NASDAQ

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