Senior Director, Technical Accounting

Septerna

$270K — $290K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Accounting or related field; active CPA required
  • 10+ years of progressive accounting experience, preferably in Big 4 and biotech or pharma
  • Expertise in U.S. GAAP, revenue recognition, and SEC reporting
  • Strong ability to research and resolve complex accounting issues
  • Experience in cross-functional collaboration and stakeholder influence
  • Exceptional analytical, organizational, and problem-solving skills
  • Proficient in managing multiple priorities in a fast-paced environment

Responsibilities

  • Lead assessment and documentation of technical accounting matters
  • Research and implement new accounting standards for U.S. GAAP compliance
  • Prepare technical memos for audit reviews and compliance support
  • Partner with Legal and Finance on complex contracts' accounting treatment
  • Support preparation of financial statements and SEC filings
  • Serve as liaison with external auditors for efficient audit processes
  • Establish and maintain scalable accounting policies and internal controls
  • Contribute to M&A transactions, including due diligence and accounting integration

Benefits

  • Comprehensive benefits package
  • Equity or stock options offered
  • Targeted annual bonus structure for full-time roles
  • Support for professional development and growth
  • Work in a collaborative, high-performing team environment
Full Job Description
THE ROLE

Septerna is seeking an experienced and highly motivated Senior Director of Technical Accounting to lead and oversee complex accounting matters and ensure compliance with U.S. GAAP across the organization. This individual will play a critical role in supporting financial reporting, evaluating technical accounting issues, and building scalable accounting policies and processes as the company grows.

The ideal candidate will bring deep technical accounting expertise, strong judgment, and the ability to operate effectively in a fast-paced biotech environment. This position will work closely with Finance, FP&A, Legal, Investor Relations, and external auditors, and will report into the Vice President, Finance and Business Operations.

Responsibilities:
  • Lead the assessment and documentation of technical accounting matters, including revenue recognition, stock-based compensation, equity transactions, leases, and collaboration/licensing agreements
  • Research, interpret, and implement new accounting standards and ensure ongoing compliance with U.S. GAAP and SEC reporting requirements
  • Prepare technical accounting memos and position papers to support conclusions and external audit reviews
  • Partner with Legal and Finance to review and structure complex contracts and transactions to ensure appropriate accounting treatment
  • Support the preparation and review of financial statements and disclosures, including 10-Ks, 10-Qs, and other SEC filings (as applicable)
  • Serve as a key liaison with external auditors, driving efficient and effective audit and review processes
  • Establish and maintain accounting policies, procedures, and internal controls to support a growing organization
  • Support M&A, business development, and financing transactions, including due diligence and accounting integration
  • Mentor team members and contribute to building a high-performing accounting function

Qualifications
  • Bachelor's degree in Accounting or related field; active CPA required
  • A minimum of 10+ years of progressive accounting experience, including public accounting (Big 4 or equivalent) and biotechnology, life sciences or pharmaceutical industry experience
  • Strong expertise in U.S. GAAP, revenue recognition, clinical trial accruals, equity, and SEC reporting in public companies
  • Proven ability to research and resolve complex accounting issues and communicate conclusions clearly
  • Experience working cross-functionally and influencing stakeholders across Finance, Legal, and business teams
  • Strong analytical, organizational, and problem-solving skills with high attention to detail
  • Ability to thrive in a fast-paced, dynamic environment and manage multiple priorities effectively
  • Collaborative, proactive, and solutions-oriented mindset with a focus on continuous improvement

The anticipated salary range for candidates who will work in South San Francisco, CA is $270,000 - $290,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location and relevant education or training. Septerna's compensation package also includes benefits, stock options, and annual target bonus for full-time positions.

Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.

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