DescriptionRole SummaryHybrid Position, requires 2 days onsite/ per week in San Rafael, CA (HQ)The Senior Director, Integrated Planning & Analytics, leads enterprise planning across demand, supply, inventory, capacity, and financial objectives through Integrated Business Planning (IBP). This role drives profitable growth, operational agility, and patient-centric outcomes across a global rare disease supply network by connecting decisions across Commercial, Clinical, Manufacturing, Quality, Regulatory, Medical Affairs, and Finance.
In a dynamic portfolio shaped by new indications, label expansions, named-patient and compassionate use programs, and clinical-to-commercial transitions, this leader strengthens supply resilience, manages risk, and builds planning capabilities for long-term growth.
As the global process owner for IBP, you will lead forward-looking decision-making across a 24-60-month horizon, including long-range capacity planning and modeling, inventory strategy, and data analytics that support reliable supply and patient access.
Key Responsibilities1. IBP Process Ownership in a Rare Disease Environment- Own the global IBP framework for rare disease planning, addressing demand variability, small batches, long lead times, and constrained capacity.
- Establish and maintain a consistent IBP cadence (Product Review, Demand Review, Supply Review, Integrated Reconciliation, Executive IBP).
- Own the S&OE (Sales & Operations Execution) process, ensuring near-term demand, supply, and inventory decisions are aligned to the broader IBP framework and escalated appropriately.
- Embed patient-centric planning principles into the IBP cycle (e.g., emergency orders, compassionate use, urgent clinical supply requests).
- Ensure seamless integration of clinical and commercial planning due to overlapping supply sources and shared manufacturing assets.
2. Rare Disease Demand, Supply & Inventory Integration- Oversee reconciliation of commercial, patient, named-patient, early-access, and clinical trial demand signals.
- Ensure supply plans reflect long cycle times, yield variability, cold-chain requirements, and CMO dependencies.
- Lead Inventory Management to define inventory policies, targets, and positioning strategies that minimize expiry while guaranteeing immediate patient access for ultra-low-volume therapies.
- Lead risk-based scenario planning for demand surges (e.g., new diagnoses, outbreaks, compassionate use clusters), supply disruptions, or single-source component issues.
3. Cross-Functional Leadership & Governance- Chair IBP forums across Commercial, Clinical Operations, Technical Operations, Manufacturing, Quality, Regulatory, Finance, and Medical.
- Establish governance and decision rights for trade-offs such as allocation priorities, safety stock strategies, and launch readiness.
- Lead structured decision-making in Executive IBP, ensuring senior leaders have clear scenarios, risks, and recommendations.
- Drive alignment across global, regional, and country planning, accounting for reimbursement and access variability.
4. People Leadership: - Lead the team of Integrating Planning & Analytics professionals, through strong development and mentoring while creating a culture of high accountability and innovation.
- Ensure there are departmental performance goals and objectives that the team of integrated planners can leverage to develop their respective objectives and provide performance feedback related to business objectives.
- Create a training curriculum to support Integrated Planning & Analytics Team's development responsibilities.
- Influence teams across the supply chain planning organization to improve their maturity and collaboration through a harmonized integrated planning playbook maximizing optimal support to the planning cycles.
5. Financial & Portfolio Integration- Partner closely with Finance, particularly during AOP/LRP cycles, to embed operational, revenue, COGS, and margin considerations into IBP.
- Integrate portfolio plans including new indications, lifecycle extensions, label expansions, and transitions from clinical supply platforms to scaled commercial supply.
- Support business case development for strategic investments (redundant capacity, alternate sites, new technology platforms) and lead long-range capacity planning/modeling to ensure the network can support future portfolio growth, new indications, and evolving patient demand.
6. Data, Systems & Analytics- Leading and enhancing performance management and visualization efforts, specifically improving dashboards that can be used across markets, supply, finance, and overall performance management
- Define the IBP technology vision with Digital/IT, including platforms for complex, low-volume, high-variability planning.
- Ensure data quality for critical demand, therapy, batch, expiry, and distribution attributes.
- Lead Data Analytics to develop advanced planning insights, improve forecast ability of ultra-small populations, and evaluate risk-based scenarios for proactive decision-making.
7. Stakeholder Engagement & Change Leadership- Drive adoption of IBP behaviors in a highly cross-functional, mission-driven rare disease culture.
- Communicate clearly with senior leadership on risks, trade-offs, and opportunities, always emphasizing patient impact.
- Build planning capability across global and regional teams and mentor planners supporting rare disease products.
- Function as an internal expert and thought leader on best-practice IBP/S&OP for rare disease and biologics.
KPIs & Metrics: This role will influence:- Patient & Service Metrics
- Supply Reliability Metrics
- Inventory & Waste Metrics
- Forecast & Financial Metrics
- IBP Process Health Metrics
QualificationsRequired:- Bachelor's degree in Supply Chain, Engineering, Business, Life Sciences, or related field.
- 12+ years of progressive supply chain or operations leadership in biotech, pharmaceutical, or rare disease environments.
- Proven leadership of global S&OP/IBP processes, including long-range capacity planning, inventory strategy, and executive decision support.
- Strong command of ERP, advanced planning systems, and analytics tools that support scenario modeling and business decisions.
- Demonstrated success leading through senior executives in complex, matrixed global organizations.
- Deep understanding of life science supply chains, including access variability, long lead times, biologics complexity, and patient-critical supply continuity.
- Strong financial acumen with proven cross-functional leadership in matrixed organizations.
Preferred:- Master's degree (MBA, MS, or equivalent).
- Experience with biologics, gene therapy, enzyme replacement therapies, or other complex rare disease modalities.
- APICS/ASCM, SCOR-P, or equivalent certification.
- Experience integrating clinical and commercial supply processes.
- Familiarity with global regulatory / GxP constraints uniquely impacting rare disease therapies.
Core Competencies- Patient-Centric Mindset - prioritizes therapy availability for individuals with life-altering conditions.
- Strategic Systems Thinking - understands complex network interactions across clinical and commercial supply, including long-range capacity and inventory trade-offs.
- Executive Influence - builds alignment, shapes decisions, and leads cross-functional forums with credibility in complex matrix environments.
- Data Analytics & Financial Acumen - translates operational scenarios into financial and patient impacts using data-driven insights and advanced planning analytics.
- Inventory Strategy - balances service, waste, and working capital through thoughtful inventory policy, positioning, and risk management.
- Risk Management - proactive identification and mitigation of rare disease supply vulnerabilities.
- Change Leadership - able to embed new planning behaviors, tools, and processes in a global organization.
Travel Requirements- International travel (10-25%) to manufacturing sites, affiliates, clinical hubs, and global planning workshops.
Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.
