Genentech

Senior Data Scientist, Gen AI Foundation

Genentech$177K — $329K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree with 5+ years of relevant experience.
  • Expertise in RAG architectures and document optimization.
  • Hands-on experience with LLM frameworks and Gen AI tools.
  • Proven ability to transform traditional ML models into agentic tools.
  • Mastery of observability tools for optimizing agentic systems.

Responsibilities

  • Design and build a scalable multi-agent infrastructure.
  • Establish governance frameworks for agents and data sources.
  • Integrate emerging technologies into Generative AI solutions.
  • Influence technical decisions aligned with business goals.
  • Collaborate with cross-functional teams for unified data strategies.
  • Mentor peers to build an AI-savvy organizational culture.
  • Ensure compliance with laws, regulations, and corporate policies.

Benefits

  • Comprehensive health and wellness programs.
  • Flexible hybrid work schedule with three days onsite.
  • Opportunities for professional development and training.
  • Inclusive workplace culture fostering collaboration.
Full Job Description

The Opportunity

The Senior Data Scientist, GenAI Foundation supports back-end product development and is a critical technical role focused on building and scaling the next generation of agentic infrastructure within Genentech. This role drives the development of extensible multi-agent systems, ensuring robust governance and the transformation of traditional services into advanced agentic components. As a key technical influencer, you will stay at the forefront of Generative AI infrastructure, security, and observability, fostering deep collaborations across the global Roche organization to deliver innovative AI solutions that solve complex healthcare challenges.

  • Scalable Infrastructure Development: Design and build an extensible, multi-agent infrastructure and the foundational systems required to transform traditional services into high-performing agentic components.

  • Enterprise Governance & Security: Establish robust governance frameworks for agents and data sources, ensuring all infrastructure meets stringent security, observability, and compliance standards (Genentech/Roche).

  • Technical Innovation & Scouting: Stay at the forefront of Generative AI infrastructure and security, proactively integrating emerging technologies to maintain a competitive edge within a complex enterprise environment.

  • Strategic Technical Leadership: Influence key technical decisions and priorities, balancing high-level business goals with the need for scalable, reliable AI systems.

  • Cross Functional Partnership: Proactively partner with cross-functional business units and global Roche stakeholders to integrate agentic solutions into broader digital strategies and foster a unified, data-driven ecosystem.

  • Collaborative AI Advocacy: Support the organization’s collective technical maturity, mentoring peers and stakeholders to build a shared "AI-savvy" culture rooted in psychological safety, high-connectedness, and iterative innovation.

  • Operational Integrity: Maintain a respectful, collaborative team culture while surfacing systemic issues to leadership and ensuring strict adherence to all laws, regulations, and corporate policies.

Who You Are

  • Bachelor's degree and 5+ years of experience in a relevant field.

  • Architectural Mastery & RAG: Expert-level command of RAG architectures and document optimization (chunking), supported by deep proficiency in vector and graph databases, SQL, and AI-generated SQL techniques.

  • Frameworks & Agentic Protocols: Hands-on experience with LLM frameworks (LangChain, LangGraph, AWS Agentcore) and a mastery of Gen AI tools, including MCP and A2A protocols for seamless system communication.

  • System Transformation & Integration: Proven ability to stay on the cutting edge of multimodal architectures, with the specific technical skill to transform traditional ML models and API services into agentic, MCP-compliant tools.

  • Observability & Performance Engineering: Comprehensive mastery of observability tools for agentic systems, with a focus on optimizing the critical trade-offs between cost, reliability, and latency.

Preferred

  • Experience in building infrastructure for Gen AI products in B2B environments.

  • Experience with multimodal Gen AI tools, especially voice-based interfaces.

  • Experience in security common protocols.

  • Experience in the healthcare, pharmaceutical, or highly regulated industries.

This position is based in South San Francisco, CA and offers a hybrid schedule working 3 days per week on campus.

Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $177,310 - $329,290.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

About Genentech

Genentech is a biotechnology company that develops and manufactures drugs for the treatment of serious medical conditions. The company was founded in 1976 and is headquartered in South San Francisco, California. Genentech's products include treatments for cancer, multiple sclerosis, and other diseases. The company is a subsidiary of Roche, a Swiss pharmaceutical company. Genentech has been recognized for its innovative research and development, and has received numerous awards for its contributions to the biotechnology industry.
Learn more about Genentech
Size
14,000 employees
Industry
Founded
1976

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