Regeneron Pharmaceuticals, Inc

Senior Analytical Scientist

Regeneron Pharmaceuticals, Inc • $78K — $128K *
Rensselaer, NY 12144In-Person
Pharmaceuticals & Biotech
5 - 7 years of experience
Today
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Job Overview by Ladders

Qualifications

  • BS/BA in Chemistry, Biochemistry, Biology, or related field with 6+ years of relevant industry experience.
  • Experience developing and validating analytical methods for iSRNA/siRNA oligonucleotides and peptide therapeutics.
  • Proficiency with LC-MS/MS, CE, ion-pair RP-HPLC, peptide mapping, and oligonucleotide characterization.
  • Track record of method transfer to QC and conducting OOS/OOT investigations.
  • Strong technical writing and presentation skills, capable of mentoring others.

Responsibilities

  • Develop and optimize analytical methods for iSRNA/siRNA and peptide modalities.
  • Design and review qualification and validation protocols for GMP release.
  • Evaluate and implement new instrumentation and technologies with collaborators.
  • Transfer control test procedures to QC, including training materials.
  • Troubleshoot method, process, and formulation issues, providing analytical support.
  • Lead investigations into OOS/OOT and customer complaints with data-driven conclusions.
  • Communicate findings and risk mitigation strategies through reports and meetings.
  • Mentor junior scientists and manage the full analytical method lifecycle.

Benefits

  • Support for career development and training opportunities.
  • Collaborative environment with cross-functional teams.
  • Engagement with advanced technologies and innovative projects.
  • Hands-on role in a supportive laboratory setting.
Full Job Description
We are seeking a Senior Scientist to join our Analytical Sciences team, supporting our Manufacturing, Process Sciences (PS), and Quality Control (QC) functions in an on-site, laboratory-based role. In this role, you will advance QC capabilities by developing robust, phase-appropriate, and lifecycle-managed analytical methods for novel modalities - including iSRNA/siRNA oligonucleotides and peptide therapeutics - while collaborating with Manufacturing, Process Sciences, Quality Control, and cross-functional CMC teams.

When & Where

Location: Tempel Lane

Work Schedule: Monday-Friday 1st shift

Travel: Occasional travel to support method transfer, vendor engagements, and program meetings

Discover Your Role

  • Develop and optimize analytical methods for product and raw materials, with a focus on iSRNA/siRNA and peptide modalities.
  • Design and review qualification and validation protocols so methods are stability-indicating and suitable for GMP release.
  • Evaluate and implement new instrumentation and technologies in partnership with collaborators and vendors.
  • Transfer control test procedures to QC, including training materials and acceptance criteria.
  • Troubleshoot method, process, and formulation issues, providing analytical support across functions.
  • Lead OOS/OOT investigations and customer complaint assessments, driving data-driven root-cause conclusions.
  • Communicate findings, risk, and mitigation strategies through technical reports and cross-functional meetings.
  • Mentor junior scientists and manage the full analytical method lifecycle, from development through retirement.

This Role Might Be for You If

  • You have hands-on experience developing and validating methods for oligonucleotide or peptide therapeutics.
  • You're comfortable working across LC-MS, CE, and other advanced analytical techniques to solve complex problems.
  • You enjoy troubleshooting and leading investigations that require clear, data-driven reasoning.
  • You communicate complex technical findings clearly to scientific and cross-functional audiences alike.
  • You take ownership of method lifecycle management and thrive in a fast-paced, science-driven environment.
  • You're energized by mentoring others and shaping analytical strategy for novel modalities.

This Role Requires

  • BS/BA in Chemistry, Biochemistry, Biology, or a related field, with 6+ years of relevant industry experience in analytical development and QC method lifecycle.
  • Demonstrated experience developing and validating analytical methods for iSRNA/siRNA oligonucleotides and peptide therapeutics.
  • Hands-on proficiency with LC-MS/MS, CE, ion-pair RP-HPLC, peptide mapping, and oligonucleotide characterization assays.
  • Proven track record of method transfer to QC, troubleshooting, and OOS/OOT investigations.
  • Strong technical writing, data integrity practices, and presentation skills, with the ability to mentor and lead.

Preferred Qualifications
  • PhD in Chemistry, Biochemistry, or a related field.
  • Experience with hybridization-based assays and peptide mapping techniques.
  • Experience applying DOE and statistical trending methodologies.
  • Level for this position will be determined based on candidate qualifications.

Salary Range (annually)
$78,700.00 - $128,700.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Pharmaceuticals & Biotech
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ
REGN
* Ladders Estimates

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