POSITION SUMMARY: Join Natera's Oncology Product Development team as a
Scientist focusing on Assay Development. You will build, validate, and troubleshoot next-generation sequencing (NGS) and cell-free DNA (cfDNA) assays used in liquid biopsy and Minimal Residual Disease (MRD) testing. Every sample represents a real person, and your work will directly impact patient care by ensuring our assays meet strict clinical diagnostic standards.
PRIMARY RESPONSIBILITIES:- Design development, verification, and validation studies using stakeholder input, driving milestones to completion within established timelines
- Integrate automated workflows with digital tracking systems, including Laboratory Information Management Systems (LIMS) such as LabVantage, and execute integration testing
- Think team by partnering directly with biostatistics, bioinformatics, and lab operations to root-cause issues using data, communicating clearly without translation layers
- Plan and execute moderate to high complexity experiments, and perform primary data analysis using tools like Excel and JMP
- Provide unvarnished, data-backed updates at project and departmental meetings regarding progress, outcomes, and next steps
- Author clear Standard Operating Procedures (SOPs), study reports, and transfer documents for production implementation
- Train team members on new SOPs and automated workflows, and provide troubleshooting support to lab operations
- Adapt to evolving science and operational needs, taking ownership of tasks that move the work forward
QUALIFICATIONS:- Ph.D. with a minimum of 2 years of industry experience, or a Master's degree with a minimum of 5 years of industry experience
KNOWLEDGE, SKILLS, AND ABILITIES: - Deep technical understanding of chemistry underlying nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologies
- Ability to independently design experiments, interpret data, and determine the next scientific step
- Extensive hands-on experience with molecular biology techniques, specifically NGS, PCR/qPCR, and nucleic acid extraction and quantification
- Experience building automated workflows and executing Laboratory Developed Tests (LDT) under CLIA/CAP guidelines is highly desired
- Ability to manage multiple priorities while operating with pace and precision
- Clear, direct communication and presentation skills with strict attention to detail
- An ownership mindset that identifies gaps, tests assumptions with data, and executes without waiting for a finished playbook
- Proven ability to author clear, precise project plans, study protocols, reports, and SOPs
Compensation & Total Rewards This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
- Annual performance incentive bonus
- Long-term equity awards
- Comprehensive health benefits (medical, dental, vision)
- 401(k) with company match
- Generous paid time off and company holidays
- Additional wellness and work-life benefits
Compensation Range
$116,800-$140,000 USD
