Job Function: Discovery & Pre-Clinical/Clinical Development
Job Sub Function: Biotherapeutics R&D
Job Category:Scientific/Technology
All Job Posting Locations:Malvern, Pennsylvania, United States of America
Job Description:About Innovative MedicineOur expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine
We are searching for the best talent for a Scientist in the Process Analytical Sciences team located in Malvern, PA.The Scientist, Process Analytical Sciences (PAS), is part of the Analytical Development (AD) Proteins organization and is responsible for accelerating large-molecule development by delivering phase-appropriate analytical testing at scale-combining high-throughput methods, automation, and streamlined data workflows to meet program timelines.
Key Responsibilities:- Conduct execution of protein-based analytical assays for biologics drug development to quantify size variants, excipient content, charge variants, bioactivity, etc.
- Troubleshoot instrumentation issues; perform root-cause investigations with SMEs/vendors and implement corrective actions.
- Thrive in a team setting in a dynamic environment, contribute technical expertise to multiple large molecule programs, be proficient with documentation, and review of analytical data
- Design and deploy Tecan-automated sample prep workflows supporting protein-based assays and day-to-day analytical testing needs.
- Create and maintain Tecan scripts/methods (liquid classes, labware definitions, prompts, sample sheets, error handling) for reliable execution.
- Train and mentor end-users to run and maintain scripts; publish templates and standard processes to build shared capability.
- Evaluate and pilot new automation devices/integrations; summarize feasibility results and recommend expansions to workflow scope.
QualificationsEducation:Minimum of a bachelor's degree in chemistry, biology, biochemistry, engineering, or related scientific/technical field with 3-5 years of relevant industry experience or a master's degree with 1-3 years of experience.
Experience and Skills:Required: - Hands-on experience with laboratory automation platforms, including Tecan (EVO/Fluent) or similar liquid-handling systems, with demonstrated capability in scripting and workflow development.
- Experience working in cross-functional environments, effectively collaborating with analytical scientists, engineers, digital/data teams, and external vendors.
- Strong background in multiple protein-based technologies (e.g., HPLC/UPLC, cIEF, CE-SDS, ELISA, cell-based assays, etc.)
Preferred:- Experience with programming or scripting concepts (e.g., EVOware, FluentControl, Python, or similar) and integration of automated systems with data platforms (ELN/LIMS).
- Demonstrated ability to train and mentor others, create standard work, and build sustainable technical capability within a team environment.
- Strong communication, organization, and project management skills, with the ability to prioritize work and deliver against timelines in a dynamic environment.
- Familiarity with regulated environments (e.g., GMP/GxP) and supporting documentation, validation, and data integrity requirements.
- Proven experience translating manual analytical or sample preparation workflows into automated solutions, supporting biologics development or protein-based assays.
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Required Skills: Preferred Skills:Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
