AbbVie

Scientist l - LBA (Ligand Binding Assay) Ops

AbbVie$75K — $95K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in biology, biochemistry, pharmacology, or a related field with at least 5 years of pharmaceutical experience, or an MS with 2+ years of relevant experience.
  • Required experience with ligand binding workflow and assay development troubleshooting.
  • Proven ability to operate and maintain laboratory equipment independently.
  • Desirable experience with lab automation technology.
  • Demonstrated independence and problem-solving skills.
  • Excellent written and verbal communication skills, with ability to draft technical reports.
  • Proficient with data analysis/documentation software including Excel, LIMS, and ELN.

Responsibilities

  • Analyze samples using ligand binding assays (PK, PD, TK, ADA) with MSD and ELISA methodologies.
  • Plan and execute pre-clinical sample analysis aligned with bioanalytical protocols and in vivo study designs.
  • Adapt analysis workflows based on a dynamically changing operational schedule for in vivo samples.
  • Interpret and present assay results, using insights to guide experimental adjustments.
  • Ensure accurate data archiving in electronic lab notebooks and rLIMS.
  • Effectively communicate experimental plans and results during lab meetings and across project teams.
  • Support day-to-day lab operations and contribute to the writing and updating of experimental protocols.

Benefits

  • Comprehensive package of paid time off including vacation, holidays, and sick leave.
  • Medical, dental, and vision insurance provided.
  • Eligibility for 401(k) retirement plan.
  • Participation in short-term incentive programs.
Full Job Description
We are seeking an independent, knowledgeable, and highly motivated Ligand Binding Assay Scientist (Scientist I) to join the Q uantitative T ranslational and A DME S ciences (QTAS) department at Abbvie Bioresearch Center in Worcester, MA. The LBA Operations Bioanalytical team at ABC QTAS conducts non-regulated, pre-clinical quantitative bioanalysis assays of large molecule therapeutics like monoclonal antibodies (mAb), multi-specific Abs, antibody-drug conjugates (ADC), antibody oligonucleotide conjugates (AOCs), and fusion proteins for Pharmacokinetic (PK), Pharmacodynamic (PD) and Toxicokinetic (TK) studies using ligand binding assays to support early development and drug discovery efforts. As a Scientist I, you will be responsible for: 1) Conducting pre-clinical sample analysis using ligand binding assays (MSD, ELISA) manually and using automated liquid handlers 2) Updating sample, protocol, and reagent management systems using electronic tools such as Laboratory Information Management System (rLIMS) and e-notebooks 3) Reporting, discussing, and QC'ing results to project teams which enable pharmacokinetic and pharmacodynamic analysis in support of oncology, immunology, neurology, and other AbbVie therapeutic portfolios. The ideal candidate will be a self-motivated, highly adaptable scientist with strong attention to details, has the ability to quickly learn new concepts, and a commitment to clear, consistent communication in a fast-paced, dynamic environment. Duties & Responsibilities: • Analyze samples by ligand binding assays (PK, PD, TK, ADA) using Meso Scale Discovery platform and colorimetric ELISA or other assay platforms. • Plan and execute sample analysis based on bioanalytical protocols and in vivo study designs on a variety of biological matrices (tissue lysates, serum, others) from a variety of species (monkey, mouse, rat). • Analyze pre-clinical in vivo samples based on a dynamically changing operational schedule. • Interpret, present, and discuss assay results; use results to guide analysis and adjust strategy. • Perform timely, accurate, and thorough data archiving in ELN and rLIMS. • Communicate experimental plans and results effectively, both verbally and in writing during regular lab meetings and with broader teams • Actively support day-to-day laboratory operations. • Write and update experimental protocols and procedures. • Independently and efficiently initiate, design, interpret, and troubleshoot operational assays. Qualifications • Bachelor's degree in biology, biochemistry, pharmacology, or related field with at least 5 years of pharmaceutical experience or MS in mentioned fields with 2+ years of relevant experience. • Experience with ligand binding workflow and assay development and troubleshooting is required. • Strong attention to detail, with demonstrated impact as an independent and self-motivated contributor. • Ability to operate and maintain laboratory equipment and reagents/material inventories independently. • Experience with lab automation is desirable. • Proven independence and problem-solving ability. • Excellent written and verbal communication skills and ability to draft technical reports. • Proficiency with computers and data analysis/documentation software including Excel, LIMS, and ELN. • Ability to summarize, communicate, and interpret bioanalytical results. • Ability and willingness to work effectively in a highly collaborative and multidisciplinary environment. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. • This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolutediscretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

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At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

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Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

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We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

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AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

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Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ

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