AbbVie

Scientist II - Molecular Biology

AbbVie • $100K — $130K *
Worcester, MA 01604In-Person
Pharmaceuticals & Biotech
5 - 7 years of experience
Today
Be an Early Applicant
Job Overview by Ladders

Qualifications

  • BS with 7+ years or MS with 5+ years in a relevant field.
  • Strong hands-on expertise in molecular biology techniques.
  • Proven experience in vector design, optimization, and validation.
  • Deep knowledge of gene regulation and expression control mechanisms.
  • Demonstrated problem-solving skills and scientific creativity.
  • Excellent communication and collaboration abilities.
  • Strong organizational skills with minimal supervision.

Responsibilities

  • Lead design and optimization of plasmids for protein expression.
  • Enhance genetic parts and vector architecture for better performance.
  • Utilize molecular biology expertise for sequence analysis and design strategies.
  • Analyze complex data to guide experimental decisions and future strategies.
  • Drive platform optimization through scientific innovation and process improvement.
  • Support genetic characterization for regulatory documentation.
  • Collaborate with cross-functional teams to align scientific and operational goals.
  • Communicate scientific findings and recommendations to stakeholders.

Benefits

  • Comprehensive benefits package including medical, dental, and vision insurance.
  • Paid time off including vacation, holidays, and sick days.
  • 401(k) plan for eligible employees.
  • Participation in short-term incentive programs.
Full Job Description
Cell Line Development, PDS&T AbbVie is seeking a highly motivated and innovative Senior Scientist to join the Molecular Biology team within Cell Line Development in PDS&T. This role supports the development of AbbVie's biologics pipeline by designing novel plasmids and optimizing genetic elements and vector architectures to enable robust recombinant protein expression and high-performing cell line development workflows. The successful candidate will bring strong molecular biology expertise, a deep understanding of gene regulation and expression control, and the ability to independently develop creative, scientifically rigorous solutions to complex technical challenges. This position offers the opportunity to shape platform capabilities through thoughtful construct engineering, experimental design, data-driven decision-making, and collaborative problem-solving in a fast-paced, cross-functional environment. Key Responsibilities
  • Lead the design and optimization of novel plasmid constructs for recombinant protein expression across multiple platforms.
  • Optimize genetic parts, regulatory elements, and vector architecture to improve expression performance, construct behavior, and platform compatibility.
  • Apply strong molecular biology expertise to support sequence analysis, construct design strategy, and experimental interpretation.
  • Analyze complex sequence, construct, and experimental data to inform design decisions and next-step strategies.
  • Contribute to platform optimization through innovation, process improvement, and scientific rigor.
  • Support genetic characterization efforts, including activities relevant to regulatory filing and development documentation.
  • Partner effectively with cross-functional teams across PDS&T and related functions to align scientific strategy with program and operational goals.
  • Communicate findings, recommendations, and scientific rationale clearly to internal stakeholders and leadership.
Qualifications
  • BS with 7+ years, MS with 5+ years.
  • Strong expertise in molecular biology with extensive hands-on laboratory and design experience
  • Demonstrated experience in vector design, expression construct optimization, and construct validation
  • Strong understanding of gene regulation, sequence-element-driven expression control, and vector architecture
  • Proven ability to independently design experiments, troubleshoot technical issues, and deliver high-quality scientific output
  • Excellent communication, collaboration, and organizational skills
  • Demonstrated scientific creativity, ownership, and ability to work with minimal supervision
Preferred
  • Experience supporting cell line development or related platform development activities
  • Familiarity with late-stage genetic characterization and support for regulatory filing activities
  • Experience with multiple integration systems and platform-specific construct requirements
  • Exposure to advanced sequence analysis tools, design software, or high-throughput molecular biology workflows
  • Familiarity with bioinformatics, data-driven modeling, and model development
  • Experience mentoring scientists or contributing to team development
Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

Explore Job Opportunities

AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

Networking and Career Advancement

At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

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Explore AbbVie Jobs

Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Pharmaceuticals & Biotech
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ
ABBV
* Ladders Estimates

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