Scientist - II

Merck Group$80K — $120K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master’s or Ph.D. in Biological Sciences or related discipline.
  • Minimum of 2 years’ focused experience in single cell omics, including cell handling and NGS library generation.
  • Proficiency in using automation tools for sample processing and library prep.
  • Direct experience with platforms such as 10X Genomics, Parse, and Scale Bio.
  • Solid understanding of single cell transcriptomics data requirements and wet lab workflows.
  • Strong analytical, problem-solving, and troubleshooting skills.
  • Preferred: experience with single cell data analysis, workflow design, and relevant publication history.

Responsibilities

  • Prepare high-quality cell and nuclei samples for single cell assays.
  • Design and execute large-scale single cell assay workflows including cell preparation and library generation.
  • Perform NGS library quantification and sequencing using Illumina platforms.
  • Collaborate with experimental biologists to develop workflow strategies and experimental plans.
  • Maintain meticulous records of workflows, procedures, and results.
  • Generate comprehensive reports and presentations to support data analysis and planning.
  • Stay updated on advancements in single cell technologies and ensure compliance with lab protocols.

Benefits

  • Opportunity to support innovative research within a cutting-edge Data, AI, and Genome Sciences department.
  • Contract role based in Cambridge, MA with full onsite engagement, promoting close collaboration with cross-functional teams.
Full Job Description
Position Description:

We are seeking a dynamic and highly skilled Scientist II with expertise in single cell omics to support innovative research initiatives within the Data, AI, and Genome Sciences department. This contract role is based in Cambridge, MA and will be fully onsite. The ideal candidate will possess hands-on experience in single cell workflows, from cell preparation through NGS library generation, with a strong emphasis on wet lab execution. The role supports discovery and validation efforts through advanced single cell assays and collaborative cross-functional contributions.

Key Responsibilities:
• Prepare high-quality cell and nuclei samples for single cell assays
• Design and execute large-scale single cell assay workflows, including cell preparation and library generation using platforms such as 10X Genomics 3'/5' and Flex assays, Parse, Scale Bio
• Perform NGS library quantification and sequencing using Illumina platforms (e.g., NovaSeq)
• Collaborate with experimental biologists to develop workflow strategies and experimental plans
• Maintain meticulous records and document workflows, procedures, and results for both computational and experimental teams
• Generate comprehensive reports and presentations to support analysis and planning
• Stay up to date with advancements in single cell technologies and related computational techniques
• Ensure rigorous compliance with laboratory protocols and documentation standards

Skills & Qualifications

Educational Background:
• Master's or Ph.D. in Biological Sciences or a related field

Core Experience and Skills:
• Minimum of 2 years of focused experience in single cell omics, including cell handling and NGS library generation
• Proficiency with automation tools for sample processing and library prep
• Strong understanding of single cell transcriptomics data requirements
• Direct experience with single cell profiling platforms (e.g., 10X Genomics, Parse, Scale Bio)
• Cell culture and cell handling experience required
• Strong analytical, problem-solving, and troubleshooting skills
• Excellent verbal and written communication skills
• Ability to work independently and collaboratively in a multidisciplinary team

Preferred Qualifications:
• Experience in analyzing single cell transcriptomic datasets
• Familiarity with immune-mediated or metabolic disease biology
• Experience designing workflows for single cell assays
• Publication history in peer-reviewed journals
• Exposure to bioinformatics tools and pipelines (nice to have)

Education:
• Master's or Ph.D. in Biological Sciences or closely related discipline

Additional Notes:
• 100% onsite (Cambridge, MA)
• Contract role (Level TBD)
• Focused exclusively on wet lab expertise (no spatial omics required)
• Experience with 10X Genomics is required; Parse and Scale Bio are a plus

About Merck Group

Merck Group Careers

There has never been a more opportune time to join Merck Group, a leading science and technology company in healthcare, life science, and performance materials. Merck Group offers a plethora of job opportunities that cater to a variety of skills and professional aspirations, making it an ideal environment for both seasoned experts and those at the start of their career journey.

Work You’ll Do

At Merck Group, every team member contributes to breakthrough innovations in healthcare, life sciences, and electronics. The company's commitment to diversity and innovation fuels its leadership in various sectors, driving growth and transformation globally. Merck Group’s career paths are diverse, offering positions that challenge individuals to use their skills in new ways every day, supported by robust training programs and development opportunities.

Explore Job Opportunities and Growth

Merck Group is not just about jobs; it's about building a career. With a vast array of positions, from research and development to marketing and sales, the company is keen on hiring and nurturing talent to lead industry transformation. Merck Group’s dedication to professional growth is evident in its comprehensive benefits package and performance management processes that aim to maximize individual potential.

Internship Programs

Starting with an internship at Merck Group can be a pivotal step in securing a prosperous career. Interns gain invaluable industry experience, working alongside seasoned professionals and engaging in projects that offer real-world applications of their studies. Internships often lead to full-time employment opportunities, providing a seamless transition from education to professional employment.

Inclusive Culture and Leadership

Merck Group is proud of its inclusive culture that embraces diversity and fosters an environment where all employees can thrive. The company’s leadership is committed to creating a workplace where diverse ideas lead to innovative outcomes. Merck Group also offers diversity training to ensure all team members are equipped to contribute to the company’s inclusive goals.

Networking and Professional Development

Employees at Merck Group are encouraged to engage in networking and professional development activities that enhance their career trajectories. The company hosts various networking events, workshops, and seminars that are designed to hone skills and foster connections within the industry. Leadership development programs are also a cornerstone, preparing employees for future roles of increased responsibility.

Stay Connected with Merck Group Careers

Interested candidates can explore open positions that match their skills and interests through the Merck Group careers page. The company values curious, creative, and solution-driven team players who are eager to make an impact.

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