10X Genomics

Scientist I, Reagents Sustaining and Applications

10X Genomics$123K — $166K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • BS, MS or PhD in relevant life sciences fields.
  • 12+ years (BS), 10+ years (MS), or 5+ years (PhD) of experience in reagent or assay development.
  • Experience with large-scale single-cell or spatial transcriptomics datasets.
  • Proficiency in experimental design and execution for process improvements.
  • Familiarity with a wide range of molecular biology techniques and equipment.
  • Expertise in single cell assays including library preparation and analysis.
  • Experience in troubleshooting quality control issues in manufacturing.

Responsibilities

  • Lead the testing of materials and workflows to enhance product performance.
  • Collaborate with teams to resolve product issues for the Chromium line.
  • Design and conduct experiments to evaluate the effects of changes on assays.
  • Implement process improvements for the Chromium product line.
  • Conduct statistical analyses of assay and quality control metrics.
  • Update and present documentation for manufacturing processes.

Benefits

  • Comprehensive health and retirement benefits.
  • Eligibility for equity grants and annual bonuses.
  • Opportunities for professional development and mentorship.
  • Dynamic and inclusive work environment encouraging innovative ideas.
Full Job Description
We are seeking a Scientist I to join the Reagent Sustaining and Applications group to lead sustaining efforts for our Chromium Single Cell products. The role interfaces with R&D, Production, Marketing, and Support to provide the best products to our customers from pre-launch to end of life.

The ideal candidate should have expertise in product development, troubleshooting complex issues, and understanding of molecular biology, including single cell assays, reagent manufacturing, and developing assays for quality control or manufacturing environments.

What you will be doing:
  • Lead efforts in testing new materials, tools, and workflows to improve 10x's state-of-the-art products.
  • Collaborate with key internal and external partners to troubleshoot and mitigate any issues that may arise in 10x's Chromium product line.
  • Design and execute experiments to assess the impact of protocol, reagent, or process changes on 10x's Assays.
  • Perform statistical analyses on key assay and QC metrics.
  • Update manufacturing documents and present results.

Minimum Qualifications:
  • BS, MS, or PhD in molecular biology, biochemistry, genetics, microbiology, analytical chemistry, or related fields.
  • 5+ years (BS), 2+ years (MS) or 1+ years (PhD) of relevant experience in reagent or assay development and optimization, preferably in the Biotechnology industry.
  • Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers.
  • Ability to design and execute experiments to measure the impact of process improvements and/or formulation changes.
  • Experience with a broad variety of molecular biology and analytical techniques including qPCR, nucleic acid isolation, use of plate readers, Bioanalyzers, gel imagers, real-time PCR instruments, etc.
  • Experience with single cell assays including cell handling, library preparation and downstream analysis.
  • Experience investigating, identifying, documenting, communicating, and resolving quality control issues in a controlled manufacturing environment.
  • Experience defining, documenting, communicating, and transferring new manufacturing workflows into controlled manufacturing environments.
  • Meticulous attention to detail and a conscientious work ethic.

Preferred Qualifications:
  • Hands-on experience with the 10x Chromium platform.
  • Experience using statistical tools, such as JMP or R to analyze complex data sets, create DOE experiments, and create data trending reports.
  • Experience with bioinformatic analysis of Next Generation Sequencing data from Illumina platforms.


Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company's total compensation package.

Pay Range

$123,100-$166,500 USD

About 10X Genomics

10x Genomics is a biotechnology company that develops and manufactures gene sequencing technology. The company's products enable researchers to study biological systems at a previously unattainable resolution, allowing them to gain a deeper understanding of the underlying mechanisms of disease. 10x Genomics' technology is used in a wide range of applications, including cancer research, immunology, and neuroscience. The company was founded in 2012 and is headquartered in Pleasanton, California.
Learn more about 10X Genomics
Size
1,239 employees
Market Cap
$3.8 billion
Industry
Net Income
-$542.7 million
Founded
2012
Revenue
$298.8 million
NASDAQ

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