The OpportunityWe are seeking a
Scientist, Global Medical to serve as a key driver of our evidence generation strategy. This role sits at the intersection of clinical research, investigator-initiated trials, and scientific publication-translating medical strategy into published evidence that shapes clinical practice and supports guideline development. The ideal candidate is an accomplished clinical researcher with a strong publication track record, deep experience in hematology or oncology, and the ability to independently advance complex research programs from concept through publication.
Investigator-Initiated Trial (IIT) Management- Lead oversight of the IIT portfolio, from concept evaluation and scientific review through study monitoring, data interpretation support, and publication collaboration
- Develop and apply rigorous evaluation criteria for IIT proposals, assessing strategic alignment, scientific merit, investigator credibility, institutional track record, and feasibility
- Serve as the primary scientific liaison with external investigators, providing scientific input on protocol design, supporting regulatory compliance awareness (CTA, IRB/EC approvals), and tracking study milestones
- Coordinate internal IIT governance processes, including concept review committees, budget and fair market value assessments, and fund disbursement oversight
- Establish and maintain a structured IIT pipeline tracker with clear stage-gating, timelines, and deliverable expectations
Clinical Trial Design & Evidence Generation- Provide scientific input on the design and execution of company-sponsored Phase IIIb/IV and adaptive clinical studies, burden of illness studies, and real-world evidence programs
- Collaborate with clinical development, biostatistics, and regulatory teams on study design, endpoint selection, and statistical analysis plans
- Identify evidence gaps aligned with medical strategy and develop research plans to address them through RCTs, RWE, and health outcomes research
- Evaluate and integrate multiple real-world data sources-including medical records, insurance databases, prescription databases, and patient registries-into the evidence generation strategy
Scientific Publication & Dissemination- Drive a publication strategy that produces high-impact manuscripts, congress abstracts, poster presentations, and review articles across the PV, ET, and MF therapeutic areas
- Author, co-author, and critically review manuscripts for submission to peer-reviewed journals, ensuring factual accuracy, scientific rigor, and compliance with ICMJE and GPP guidelines
- Collaborate with KOLs and academic investigators to develop consensus guidelines, journal supplements, and Delphi consensus study outputs
- Ensure all publications align with the integrated evidence plan and support NCCN guideline submissions and payer evidence needs
Cross-Functional Collaboration & Scientific Leadership- Partner with the MSL team, Medical Affairs leadership, and Commercial Analytics & Insights to translate field insights and medical questions into actionable research hypotheses
- Support the development and maintenance of a medical question (CQ) map that links KOL insights, evidence gaps, and ongoing research activities
- Contribute scientific expertise to advisory boards, speaker programs, and internal training initiatives
- Prepare evidence summaries and data packages for executive leadership and regulatory interactions
Required Qualifications- MD, PhD, or MD/PhD from an accredited institution; terminal degree strongly preferred
- Minimum 5 years of clinical research experience at a top-tier US academic medical institution or equivalent research-intensive environment
- Demonstrated publication track record with first-author or senior-author peer-reviewed publications in hematology, oncology, or a closely related field
- Direct experience managing investigator-initiated trials, including protocol development, IRB/EC submissions, and investigator engagement
- Deep understanding of clinical trial design, biostatistics, and real-world evidence methodologies
- Strong knowledge of regulatory requirements for clinical research, including ICH-GCP, ICMJE, and GPP guidelines
- Proven ability to work independently, manage multiple complex projects simultaneously, and drive programs to completion with minimal supervision
- Excellent scientific writing skills with the ability to translate complex clinical data into clear, publication-ready manuscripts and evidence summaries
Preferred Qualifications- Clinical or research background in hematology/oncology, with specific experience in myeloproliferative neoplasms (PV, ET, MF) or interferon-based therapies
- Prior pharmaceutical or biotech industry experience in Medical Affairs, clinical development, or evidence generation roles
- Experience with NCCN guideline submissions or other clinical guideline development processes
- Experience designing and executing Delphi consensus studies or structured expert elicitation programs
- Familiarity with health economics and outcomes research (HEOR) and value-based evidence frameworks
- Track record of successful collaboration with KOLs and external academic investigators
- Bilingual capabilities (English and Mandarin) are a plus but not required
The expected salary range for this position based on greater Boston, MA location is $160,000-$205,000. Actual salary pay will be based on multiple factors, including geographic location, experience, qualifications, and other job-related factors permitted by law.
What We Offer- A high-impact role with direct visibility to executive leadership and the opportunity to shape the evidence strategy for a first-in-class therapeutic across multiple indications
- Ownership of a growing IIT portfolio and publication pipeline in an organization committed to scientific excellence and evidence-based medicine
- A collaborative, intellectually rigorous Medical Affairs team with a compliance-first culture and clearly defined governance structures
- Competitive compensation, comprehensive benefits, and the flexibility of a remote-first working environment
Benefits of working with our team:PharmaEssentia USA strives every day to improve the lives of patients as well as our employees. As a valued member of PharmaEssentia USA, you will enjoy the following benefits:
- Comprehensive medical coverage
- Dental and vision coverage
- Generous paid time-off
- 401(k) retirement plan with competitive company match
- Medical & Dependent Care Flexible Spending Account
- Up to $150 monthly cell phone reimbursement
- Employee Assistance Program
