Summary

Experienced medicinal chemist who is seeking to lead and contribute to the drug discovery portfolio in the Protein Homeostasis Thematic Research Center in our San Diego Discovery Chemistry group.

We are seeking a talented and highly motivated individual with a strong background in medicinal chemistry to join our Global Discovery Chemistry, Therapeutic Discovery Sciences team in San Diego. The successful candidate will contribute and lead a team of scientists that engage in rational design of new agents for the potential treatment of diverse oncology indications. The individual will apply modern drug design principles to solve medicinal chemistry problems relevant to the Protein Homeostasis Thematic Research Center project portfolio in collaboration with a broad group of scientists.

Responsibilities

Lead end-to-end medicinal chemistry programs from discovery through IND, driving strategy, execution, and delivery of high-impact oncology assets
Design and advance novel compounds using state-of-the-art drug design approaches, integrating structural biology, ADME, and computational insights
Partner across multidisciplinary teams to accelerate decision-making, shape portfolio strategy, and deliver transformative therapeutics
Build, mentor, and lead high-performing scientific teams, fostering a culture of innovation, accountability, and scientific excellence within and outside direct reporting lines
Clearly articulate program strategy, data, opportunities, and risks to senior leadership and key stakeholders
As a member of the San Diego Chemistry Leadership team, drive the scientific, strategic, and operational direction of the San Diego medicinal chemistry organization, including portfolio prioritization, resource allocation, talent development, and representation in senior leadership decision-making

Additional Qualifications/Responsibilities

Basic qualifications

Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
M.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
B.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience
4+ years of program leadership experience in all drug discovery phases from program initiation to development candidate identification
Excellent communication skills, including the presentation of strategy, key data, issues and accomplishments to other members of the organization.
Experience in the field of protein degradation or induced proximity a plus
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If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

San Diego - CA - US: $201,590 - $244,275