Incyte

Research / Sr. Research Investigator, Quantitative Pharmacology

Incyte$90K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in Pharmacometrics, Clinical Pharmacology, Applied Mathematics, Statistics, Engineering, or related field.
  • 0 to 2 years of post-doctoral experience in pharmacometrics or clinical pharmacology.
  • Hands-on experience with NONMEM and R for pharmacometrics analyses.
  • Excellent communication skills for collaboration with teams.
  • Strong time management skills for handling multiple tasks.

Responsibilities

  • Conduct model-based analyses including population pharmacokinetics (PK) and pharmacokinetics/pharmacodynamics (PK/PD).
  • Assist in identifying avenues for advancing understanding via modeling and simulation.
  • Support development of model-informed drug development (MIDD) strategies for clinical studies.
  • Communicate results and conclusions of analyses through reports and presentations.
  • Stay updated on scientific advancements in pharmacology and apply this knowledge to drug development.
  • Contribute to peer-reviewed publications and internal scientific communications.

Benefits

  • Mentorship and guidance from experienced team members.
  • Opportunities for collaboration with diverse teams across the organization.
  • Involvement in impactful projects within drug development phases.
  • Access to ongoing scientific training and research opportunities.
Full Job Description
We are seeking a pharmacometrician to join our Clinical and Quantitative Pharmacology organization in Translational Medicine. A Research Investigator or Senior Research Investigator supports the execution of model-based analyses for clinical drug development and is expected to contribute to key programs under mentorship and guidance. This role will be responsible for applying model-informed drug development (MIDD) approaches to support decision-making across phases of drug development. Candidates will be evaluated on a case-by-case basis as to whether their experience aligns with the Research Investigator or Senior Research Investigator requirements. Essential Functions of the Job (Key responsibilities) • Conducts model-based analyses including population pharmacokinetics (PK) and pharmacokinetics/pharmacodynamics (PK/PD), and exposure-response modeling under the guidance of senior team members. • Assists in identifying opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy, and safety within assigned projects. • Supports the development of MIDD strategies to optimize prospective studies and inform clinical development in collaboration with partners (clinical pharmacology, biostatistics, regulatory, and clinical development teams). • Communicates results, conclusions, and assumptions of pharmacometrics analyses to internal audiences in written reports and oral presentations. • Stays current with scientific advancements and regulatory trends in clinical pharmacology and pharmacometrics, and applies this knowledge to support drug development goals. • Contributes to peer-reviewed publications and internal scientific communications. Qualifications (Minimal acceptable level of education, work experience, and competency) • Ph.D. in Pharmacometrics, Clinical Pharmacology, Applied Mathematics, Statistics, Engineering, or a related field. • 0 to 2 years of related post-doctoral experience in pharmacometrics or clinical pharmacology (industry or academic). • Hands-on experience with NONMEM and R for pharmacometrics analyses. • Excellent communication skills and ability to collaborate with cross-functional teams. • Strong time management skills and ability to balance execution of multiple tasks to accomplish program goals. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

About Incyte

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of proprietary therapeutics. The company was founded in 1991 and is headquartered in Wilmington, Delaware. Incyte's main focus is on oncology, inflammation, and autoimmunity. The company's flagship product, Jakafi, is a JAK1/JAK2 inhibitor used to treat myelofibrosis and polycythemia vera. Incyte has a number of other products in development, including itacitinib, a JAK1 inhibitor for the treatment of graft-versus-host disease, and pemigatinib, a FGFR inhibitor for the treatment of cholangiocarcinoma.
Learn more about Incyte
Size
2,094 employees
Market Cap
$17.6 billion
Industry
Net Income
-$295.7 million
Founded
1991
5 Year Trend
+22%
Revenue
$2.6 billion
NASDAQ

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