Elanco Animal Health

Research Scientist

Elanco Animal Health • $75K — $95K *
Indianapolis, IN 46227In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
3 weeks ago
Job Overview by Ladders

Qualifications

  • Ph.D. in Immunology, Biochemistry, Biology, or related field; OR M.S. with 3+ years industry experience; OR B.S. with 5+ years industry experience.
  • Proven hands-on experience developing and validating ligand-binding assays (LBAs).
  • Strong grasp of pharmacokinetics principles for biologic drugs.
  • Proficiency with immunoassay platforms; ELISA experience required.
  • Excellent problem-solving skills and scientific rigor.

Responsibilities

  • Design, develop, and optimize ligand-binding assays for monoclonal antibodies.
  • Conduct bioanalytical methods in compliance with SOPs and regulations; assess assay performance metrics.
  • Analyze preclinical and clinical samples to deliver high-quality data.
  • Manage critical reagents to maintain assay consistency and performance.
  • Independently troubleshoot technical assay issues and evaluate new technologies.
  • Document all procedures and results meticulously in an electronic lab notebook.
  • Collaborate effectively within a cross-functional matrix environment.

Benefits

  • Multiple relocation packages
  • Two weeklong shutdowns in the US in addition to PTO
  • 8-week parental leave
  • 9 Employee Resource Groups
  • Annual bonus offering
  • Flexible work arrangements
  • Up to 6% 401K matching
Full Job Description
We are seeking a skilled and detail-oriented Bioanalytical Scientist to join our Large Molecule Assay Development team within Research and Breakthrough Innovation at Elanco. This laboratory-based position is focused on the development, validation, and execution of ligand-binding assays (LBAs) to quantify monoclonal antibodies and other protein therapeutics in biological matrices. The ideal candidate will have extensive hands-on experience with immunoassay platforms and a deep understanding of the unique challenges associated with the bioanalysis of large molecules.

Key Responsibilities
  • Design, develop, and optimize ligand-binding assays (e.g., ELISA, MSD, Gyros) for the quantification of monoclonal antibodies in various biological fluids.
  • Perform fit-for-purpose bioanalytical methods according to internal SOPs and global regulatory guidelines, assessing assay performance characteristics such as accuracy, precision, selectivity, sensitivity, and stability.
  • Analyze samples from preclinical and clinical studies to provide high-quality data to our project teams
  • Characterize, conjugate, and manage critical reagents (e.g., capture/detection antibodies, standards) to ensure long-term assay consistency and performance.
  • Independently troubleshoot and resolve technical issues with assays. Evaluate and implement new technologies and platforms to improve assay sensitivity, throughput, and robustness.
  • Meticulously document all experimental procedures and results in an electronic lab notebook (ELN).
  • Work in a highly collaborative, cross-functional matrix environment, communicating effectively with team members at various levels.


What You Need to Succeed
Required Qualifications

  • Ph.D. in Immunology, Biochemistry, Biology, or a related scientific discipline; OR
  • M.S. with 3+ years of relevant industry experience; OR
  • B.S. with 5+ years of relevant industry experience.
  • Demonstrated hands-on experience developing, validating, and running ligand-binding assays (LBAs).
  • Strong understanding of the principles of pharmacokinetics for biologic drugs.
  • Proficiency with common immunoassay platforms, with ELISA experience as a minimum.


What Will Give You a Competitive Edge
Preferred Qualifications

  • Hands-on experience with advanced immunoassay platforms such as Meso Scale Discovery (MSD), Gyros, or Quanterix.
  • Experience with the development and validation of immunogenicity (Anti-Drug Antibody, ADA) assays.
  • Familiarity with cell-based neutralizing antibody (NAb) assays.
  • Strong data analysis skills and experience with relevant software (e.g., SoftMax Pro, Benchling).
  • Excellent problem-solving abilities and a high degree of scientific rigor.


Elanco Benefits and Perks:

We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
  • Multiple relocation packages
  • Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
  • 8-week parental leave
  • 9 Employee Resource Groups
  • Annual bonus offering
  • Flexible work arrangements
  • Up to 6% 401K matching

About Elanco Animal Health

Elanco Animal Health is an American pharmaceutical company that develops and produces products for animal health. The company was founded in 1954 and is headquartered in Greenfield, Indiana. Elanco produces a wide range of products for both livestock and pets, including vaccines, antibiotics, and parasiticides. The company operates in more than 90 countries and has a global workforce of over 5,500 employees. Elanco was spun off from Eli Lilly and Company in 2018 and became a publicly traded company in September of that year. The company is listed on the New York Stock Exchange under the ticker symbol ELAN.
Learn more about Elanco Animal Health
Size
9,000 employees
Market Cap
$5.3 billion
Industry
Pharmaceuticals & Biotech
Net Income
-$560 million
5 Year Trend
+10.3%
Revenue
$3.2 billion
NASDAQ
ELAN
* Ladders Estimates

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