Research Scholar - Director of the Protein Design and Analysis Core

The Research Scholar role will serve as the Director of the Protein Design and Analysis Core provides visionary scientific and operational leadership for a multidisciplinary core facility dedicated to the de novo design, engineering, characterization, and structural analysis of proteins. The Director oversees a team of scientists, engineers, and technical staff, and serves as a strategic partner to internal research programs and external collaborators. This role demands expertise at the intersection of computational protein design, structural biology, and biophysical characterization, combined with the management acumen to operate a high-throughput, service-oriented research core.

Qualified candidates will have aPh.D. in Biochemistry, Structural Biology, Biophysics, Computational Biology, Bioengineering, or a closely related field with a minimum of 8-10 years of post-doctoral research or industry experience, with at least 3-5 years in a leadership or supervisory role.

Demonstrated deep expertise in protein expression systems (bacterial, mammalian, insect), purification, and quality control is essential as well as a strong command of biophysical characterization techniques (SPR, ITC, SEC-MALS, CD, DLS, HDX-MS). Proficiency in structural biology methods (X-ray crystallography and/or cryo-EM) and associated software pipelines is required, with hands-on experience with computational protein design platforms (Rosetta, AlphaFold, ESMFold, or equivalent) and relevant scripting languages (Python, PyMOL scripting, etc.).

Highly qualified candidates will have a proven track record of scientific productivity evidenced by peer-reviewed publications in high-impact journals, with demonstrated ability to manage complex, multi-stakeholder projects and lead interdisciplinary teams.